Department of Pharmacology; Department of Pediatrics
Base Sequence; DNA, Viral; *Genes, Viral; Herpesviridae; Molecular Sequence Data; *Repetitive Sequences, Nucleic Acid
Life Sciences | Medicine and Health Sciences
Herpesvirus sylvilagus is a lymphotropic (type gamma) herpesvirus of cottontail rabbits (Sylvilagus floridanus). Analysis of virion DNA of herpesvirus sylvilagus has revealed that the genome consists of one stretch of about 120 kilobase pairs of internal, unique DNA flanked by a variable number of 553-base-pair tandem repeats. The G + C content of the repetitive DNA is extremely high (83%), as determined by sequencing. The organization of the herpesvirus sylvilagus genome is, therefore, similar to that of the primate lymphotropic viruses herpesvirus saimiri and herpesvirus ateles.
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Citation: J Virol. 1989 Feb;63(2):1010-4.
Journal of virology
Medveczky, Maria M.; Geck, Peter; Clarke, Chester H.; Byrnes, Julie; Sullivan, John L.; and Medveczky, Peter G., "Arrangement of repetitive sequences in the genome of herpesvirus Sylvilagus" (1989). Open Access Articles. 1584.