PubMed ID
18094494
UMMS Affiliation
Department of Orthopedics
Date
12-21-2007
Document Type
Article
Subjects
Animals; Biomedical Engineering; Bone Development; Bone Diseases; Bone Transplantation; Cells, Cultured; Chemical Engineering; Disease Models, Animal; Durapatite; Ethylene Glycol; Graft Survival; Humans; Materials Testing; Osteoblasts; Polymers; Polymethacrylic Acids; Polyurethanes; Prostheses and Implants; Rats; Stress, Mechanical; Stromal Cells; Weight-Bearing
Disciplines
Biotechnology | Life Sciences | Medicine and Health Sciences | Musculoskeletal System | Orthopedics
Abstract
The design of synthetic bone grafts that possess structural and biochemical microenvironment emulating the extracellular matrix of bone and exhibit good surgical handling characteristics is of significant importance to orthopedic applications. Using a combination of chemical and engineering tools, our lab has developed a number of osteogenic composite bone grafts that possess elastomeric or self-deployable shape memory properties facilitating the repair and regeneration of segmental bony defects.
Rights and Permissions
Citation: J Musculoskelet Neuronal Interact. 2007 Oct-Dec;7(4):325. Link to article on publisher's website