Thymic uptake of iodine-131 in the anterior mediastinum

UMMS Affiliation

Department of Radiology, Division of Nuclear Medicine

Publication Date


Document Type



Adenocarcinoma, Follicular; Adult; Carcinoma, Papillary; Diagnosis, Differential; Humans; Iodine Radioisotopes; Male; Mediastinal Neoplasms; Mediastinum; Thymus Gland; Thymus Hyperplasia; Thyroid Neoplasms; Thyroidectomy


Life Sciences | Medicine and Health Sciences


Two thyroidectomized patients with a history of differentiated thyroid carcinoma are presented who had nonmetastatic mediastinal 131I uptake following therapeutic doses of 131I. Chest CT scans in both patients demonstrated an anterior mediastinal mass. Surgical excision in one patient and a percutaneous CT-guided fine needle aspiration biopsy in the other disclosed normal thymus tissue. Iodine-131 uptake in the anterior mediastinum in patients thyroidectomized for follicular or papillary thyroid carcinoma may represent the thymus.

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Citation: J Nucl Med. 1996 Jun;37(6):991-2.

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Link to Article in PubMed

Journal/Book/Conference Title

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

PubMed ID