UMMS Affiliation

Center for Comparative Neuroimaging; Department of Psychiatry

Date

1-7-2005

Document Type

Article

Subjects

Animals; Animals, Suckling; Brain; Brain Mapping; Cocaine; Dopamine; Female; Image Processing, Computer-Assisted; Injections, Intraventricular; Lactation; Magnetic Resonance Imaging; Maternal Behavior; Neural Pathways; Rats; Rats, Sprague-Dawley; *Reward; Time Factors

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

Nursing has reciprocal benefits for both mother and infant, helping to promote maternal behavior and bonding. To test the "rewarding" nature of nursing, functional magnetic resonance imaging was used to map brain activity in lactating dams exposed to their suckling pups versus cocaine. Suckling stimulation in lactating dams and cocaine exposure in virgin females activated the dopamine reward system. In contrast, lactating dams exposed to cocaine instead of pups showed a suppression of brain activity in the reward system. These data support the notion that pup stimulation is more reinforcing than cocaine, underscoring the importance of pup seeking over other rewarding stimuli during lactation.

Rights and Permissions

Citation: J Neurosci. 2005 Jan 5;25(1):149-56. Link to article on publisher's site

DOI of Published Version

10.1523/JNEUROSCI.3156-04.2005

Related Resources

Link to Article in PubMed

Journal Title

The Journal of neuroscience : the official journal of the Society for Neuroscience

PubMed ID

15634776

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