Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2015

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Impact of Thromboprophylaxis across the US Acute Care Setting, Wei Huang, Frederick A. Anderson Jr., Sophie K. Rushton-Smith, and Alexander T. Cohen

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Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities, Kamesh Narasimhan, Samuel A. Lambert, Ally Yang, Jeremy Riddell, Sanie Mnaimneh, Hong Zheng, Mihai Albu, Hamed S. Najafabadi, John S. Reece-Hoyes, Juan Fuxman Bass, Albertha J. M. Walhout, Matthew T. Weirauch, and Timothy R. Hughes

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An efficient and sensitive method for preparing cDNA libraries from scarce biological samples, Catherine H. Sterling, Isana Veksler-Lublinsky, and Victor R. Ambros

Publications from 2014

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The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria, Lis R.V. Antonelli, Fabiana M.S. Leoratti, Pedro A.C. Costa, Bruno C. Rocha, Suelen Q. Diniz, Mauro S. Tada, Dhelio B. Pereira, Andrea Teixeira-Carvalho, Douglas T. Golenbock, Ricardo Goncalves, and Ricardo T. Gazzinelli

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The home environment and childhood obesity in low-income households: indirect effects via sleep duration and screen time, Bradley M. Appelhans, Stephanie L. Fitzpatrick, Hong Li, Vernon Cail, Molly E. Waring, Kristin L. Schneider, Matthew C. Whited, Andrew M. Busch, and Sherry L. Pagoto

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Human breast progenitor cell numbers are regulated by WNT and TBX3, Lisa M. Arendt, Jessica St. Laurent, Ania Wronski, Silvia Caballero, Stephen Lyle, Stephen P. Naber, and Charlotte Kuperwasser

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Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection, Marco A. Ataide, Warrison A. Andrade, Dario S. Zamboni, Donghai Wang, Maria do Carmo Souza, Bernardo S. Franklin, Samir Elian, Flaviano S. Martins, Dhelio Pereira, George W. Reed, Katherine A. Fitzgerald, Douglas T. Golenbock, and Ricardo T. Gazzinelli

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High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody, Gregory J. Babcock, Sowmya Iyer, Heidi L. Smith, Yan Wang, Kirk Rowley, Donna M. Ambrosino, Phillip D. Zamore, Brian G. Pierce, Deborah C. Molrine, and Zhiping Weng

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Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals, Shashi Bala, Miguel Marcos, Arijeet Gattu, Donna Catalano, and Gyongyi Szabo

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Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan, Ankita Bansal, Eun-Soo Kwon, Darryl Conte Jr., Haibo Liu, Michael J. Gilchrist, Lesley T. MacNeil, and Heidi A. Tissenbaum

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Protective immunity and safety of a genetically modified influenza virus vaccine, Rafael Polidoro Alves Barbosa, Ana Paula Carneiro Salgado, Cristiana Couto Garcia, Bruno Galvao Filho, Ana Paula de Faria Paula de Faria Goncalves, Braulio Henrique Freire Lima, Gabriel Augusto Oliveira Lopes, Milene Alvarenga Rachid, Andiara Cristina Cardoso Peixoto, Danilo Bretas de Oliveira, Marco Antonio Ataide, Carla Aparecida Zirke, Tatiane Marques Cotrim, Erica Azevedo Costa, Gabriel Magno de Freitas Almeida, Remo Castro Russo, Ricardo T. Gazzinelli, and Alexandre de Magalhaes Vieira Machado

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The relationship between subnormal peak-stimulated growth hormone levels and auxological characteristics in obese children, Jefferson Barrett, Louise S. Maranda, and Benjamin U. Nwosu

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Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA, Hanni Bartels and Jeremy Luban

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A conserved dopamine-cholecystokinin signaling pathway shapes context-dependent Caenorhabditis elegans behavior, Raja Bhattacharya, Denis Touroutine, Belinda Barbagallo, Jason Climer, Christopher M. Lambert, Christopher M. Clark, Mark J. Alkema, and Michael M. Francis

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The spatial dynamics of dengue virus in Kamphaeng Phet, Thailand, Piraya Bhoomiboonchoo, Robert V. Gibbons, Angkana Huang, In-Kyu Yoon, Darunee Buddhari, Ananda Nisalak, Natkamol Chansatiporn, Mathuros Thipayamongkolgul, Siripen Kalanarooj, Timothy Endy, Alan L. Rothman, Anon Srikiatkhachorn, Sharone Green, Mammen P. Mammen, Derek A. Cummings, and Henrik Salje

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A survey study of evidence-based medicine training in US and Canadian medical schools, Maria A. Blanco, Carol F. Capello, Josephine L. Dorsch, Gerald (Jerry) Perry, and Mary L. Zanetti

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Dengue virus neutralizing antibody levels associated with protection from infection in Thai cluster studies, Darunee Buddhari, Jared Aldstadt, Timothy P. Endy, Anon Srikiatkhachorn, Butsaya Thaisomboonsuk, Chonticha Klungthong, Ananda Nisalak, Benjawan Khuntirat, Richard G. Jarman, Stefan Fernandez, Stephen J. Thomas, Thomas W. Scott, Alan L. Rothman, and In-Kyu Yoon

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Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90, Terence N. Bukong, Fatemeh Momen-Heravi, Karen Kodys, Shashi Bala, and Gyongyi Szabo

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A deterministic model predicts the properties of stochastic calcium oscillations in airway smooth muscle cells, Pengxing Cao, Xiahui Tan, Graham Donovan, Michael J. Sanderson, and James Sneyd

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Estudio Parto: postpartum diabetes prevention program for hispanic women with abnormal glucose tolerance in pregnancy: a randomised controlled trial - study protocol, Lisa Chasan-Taber, Bess H. Marcus, Milagros C. Rosal, Katherine L. Tucker, Sheri J. Hartman, Penelope S. Pekow, Barry Braun, Tiffany A. Moore Simas, Caren G. Solomon, Joann E. Manson, and Glenn Markenson

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Psychopathic traits modulate brain responses to drug cues in incarcerated offenders, Lora M. Cope, Gina M. Vincent, Justin L. Jobelius, Prashanth K. Nyalakanti, Vince D. Calhoun, and Kent A. Kiehl

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Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA, Alberto De Iaco and Jeremy Luban

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Quitters referring smokers: a quitline chain-referral pilot study, Kathryn L. Delaughter, Julie E. Volkman, Barrett D. Phillips, and Thomas K. Houston

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Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast, Noah Dephoure, Sunyoung Hwang, Ciara O'Sullivan, Stacie E. Dodgson, Steven P. Gygi, Angelika Amon, and Eduardo M. Torres

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IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion, Tanay M. Desai, Mariana Marin, Christopher R. Chin, George Savidis, Abraham L. Brass, and Gregory B. Melikyan

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hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3, Jason R. Dobson, Hanna Taipaleenmaki, Yu-Jie Hu, Deli Hong, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Jane B. Lian, and Jitesh Pratap

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PI3K signaling and Stat92E converge to modulate glial responsiveness to axonal injury, Johnna E. Doherty, Amy E. Sheehan, Rachel Bradshaw, A. Nicole Fox, Tsai-yi Lu, and Marc R. Freeman

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Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice, Shuping Dou, John Virostko, Mary Rusckowski, Dale L. Greiner, Alvin C. Powers, and Guozheng Liu

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TLR4 activation induces IL-1ss release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung, Suffwan Eltom, Maria G. Belvisi, Liang Yew-Booth, Bilel Dekkak, Sarah A. Maher, Eric D. Dubuis, Victoria Jones, Kate A. Fitzgerald, and Mark A. Birrell

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Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors, Itzel Escobedo-Avila, Fernanda Vargas-Romero, Anayansi Molina-Hernandez, Rodrigo Lopez-Gonzalez, Daniel Cortes, Juan A. De Carlos, and Ivan Velasco

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Genetic models of apoptosis-induced proliferation decipher activation of JNK and identify a requirement of EGFR signaling for tissue regenerative responses in Drosophila, Yun Fan, Shiuan Wang, Jacob Hernandez, Vildan Betul Yenigun, Gillian Hertlein, Caitlin E. Fogarty, Jillian L. Lindblad, and Andreas Bergmann

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Approaches for classifying the indications for colonoscopy using detailed clinical data, Hirut Fassil, Kenneth F. Adams, Sheila Weinmann, V. Paul Doria-Rose, Eric Johnson, Andrew E. Williams, Douglas A. Corley, and Chyke A. Doubeni

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Evaluation of naturally acquired IgG antibodies to a chimeric and non-chimeric recombinant species of Plasmodium vivax reticulocyte binding protein-1: lack of association with HLA-DRB1*/DQB1* in malaria exposed individuals from the Brazilian Amazon, Amanda Ribeiro Ferreira, Balwan Singh, Monica Cabrera-Mora, Alana Cristina Magri De Souza, Maria Teresa Queiroz Marques, Luis Cristovao Sobrino Porto, Fatima Santos, Dalma Maria Banic, J. Mauricio Calvo-Calle, Joseli Oliveira-Ferreira, Alberto Moreno, and Josue Da Costa Lima-Junior

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Arf4 is required for Mammalian development but dispensable for ciliary assembly, John A. Follit, Jovenal T. San Agustin, Julie A. Jonassen, Tingting Huang, Jaime A. Rivera-Perez, Kimberly D. Tremblay, and Gregory J. Pazour

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Influenza virus drug resistance: a time-sampled population genetics perspective, Matthieu Foll, Yu Ping Poh, Nicholas Renzette, Anna Ferrer Admetlla, Claudia Bank, Hyunjin Shim, Anna Sapfo Malaspinas, Gregory Ewing, Ping Liu, Daniel Wegmann, Daniel R. Caffrey, Konstantin B. Zeldovich, Daniel N. A. Bolon, Jennifer Wang, Timothy F. Kowalik, Celia A. Schiffer, Robert W. Finberg, and Jeffrey D. Jensen

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Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score, Keith A. A. Fox, Gordon FitzGerald, Etienne Puymirat, Wei Huang, Kathryn Carruthers, Tabassome Simon, Pierre Coste, Jacques Monsegu, Phillippe Gabriel Steg, Nicolas Danchin, and Frederick A. Anderson Jr.

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Upper extremity injury management by non-physician emergency practitioners in rural Uganda: A pilot study, Daniel S. Frank, Katie Dunleavy, Rashidah Nambaziira, Irene Nayebare, Bradley Dreifuss, and Mark Bisanzo

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Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters, Juan I. Fuxman Bass, Alex M. Tamburino, Akihiro Mori, Nathan Beittel, Matthew T. Weirauch, John S. Reece-Hoyes, and Albertha J. M. Walhout

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A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection, Don B. Gammon, Sophie Duraffour, Daniel K. Rozelle, Heidi Hehnly, Rita Sharma, Michael E. Sparks, Cara C. West, Ying Chen, James J. Moresco, Graciela Andrei, John H. Connor, Darryl Conte Jr., Dawn E. Gundersen-Rindal, William L. Marshall, John R. Yates, Neal S. Silverman, and Craig C. Mello

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Fidelity of Histone Gene Regulation is Obligatory for Genome Replication and Stability, Prachi N. Ghule, Ronglin Xie, Ricardo F. Medina, Jennifer L. Colby, Stephen N. Jones, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein

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An improved predictive recognition model for Cys2-His2 zinc finger proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J. Keith Joung, Scot A. Wolfe, and Gary D. Stormo

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The comparative effectiveness of abatacept versus anti-tumour necrosis factor switching for rheumatoid arthritis patients previously treated with an anti-tumour necrosis factor, Leslie R. Harrold, George W. Reed, Joel M. Kremer, Jeffrey R. Curtis, Daniel H. Solomon, Marc C. Hochberg, and Jeffrey D. Greenberg

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Teaching tobacco dependence treatment and counseling skills during medical school: rationale and design of the Medical Students helping patients Quit tobacco (MSQuit) group randomized controlled trial, Rashelle B. Hayes, Alan C. Geller, Linda C. Churchill, Denise G. Jolicoeur, David M. Murray, Abigail Shobend, Sean P. David, Michael Adams, Kola Okuyemi, Randy Fauver, Robin Gross, Frank Leone, Rui Xiao, Jonathan Waugh, Sybil L. Crawford, and Judith K. Ockene

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Myogenic Enhancers Regulate Expression of the Facioscapulohumeral Muscular Dystrophy-Associated DUX4 Gene, Charis L. Himeda, Celine Debarnot, Sachiko Homma, Mary Lou Beermann, Jeffrey B. Miller, Peter L. Jones, and Takako I. Jones

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MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis, Andrew G. Hoss, Vinay K. Kartha, Xianjun Dong, Jeanne C. Latourelle, Alexandra Dumitriu, Tiffany C. Hadzi, Marcy E. Macdonald, James F. Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, and Richard H. Myers

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Profiles of acute cytokine and antibody responses in patients infected with avian influenza A H7N9, Rui Huang, Lu Zhang, Qin Gu, Yi-Hua Zhou, Yingying Hao, Kui Zhang, Yong Liu, Danjiang Dong, Shixia Wang, Zuhu Huang, Shan Lu, and Chao Wu

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The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins, Andree Hubber, Kohei Arasaki, Fubito Nakatsu, Camille Hardiman, David G. Lambright, Pietro De Camilli, Hiroki Nagai, and Craig R. Roy

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Rictor/mTORC2 Loss in the Myf5 Lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease, Chien-Min Hung, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Huawei Li, Clary B. Clish, Simone Hettmer, Amy J. Wagers, and David A. Guertin

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Emergency department patient safety incident characterization: an observational analysis of the findings of a standardized peer review process, Zach K. Jepson, Chad E. Darling, Kevin A. Kotkowski, Steven B. Bird, Michael W. Arce, Gregory A. Volturo, and Martin A. Reznek

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A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling beta-glucan microparticles, Magdia De Jesus, Gary R. Ostroff, Stuart M. Levitz, Toni R. Bartling, and Nicholas J. Mantis

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Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses, Hiroshi Kataoka, Hajime Kono, Zubin Patel, and Kenneth L. Rock

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Clinical disease activity and acute phase reactant levels are discordant among patients with active rheumatoid arthritis: acute phase reactant levels contribute separately to predicting outcome at one year, Jonathan Kay, Olga Morgacheva, Susan P. Messing, Joel M. Kremer, Jeffrey D. Greenberg, George W. Reed, Ellen M. Gravallese, and Daniel E. Furst

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Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells, Nicola A. Kearns, Ryan M. J. Genga, Metewo Selase Enuameh, Manuel Garber, Scot A. Wolfe, and Rene Maehr

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The islet estrogen receptor-alpha is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes, Gamze Kilic, Ana I. Alvarez-Mercado, Bader Zarrouki, Darren Opland, Chong Wee Liew, Laura C. Alonso, Martin G. Myers Jr, Jean-Christophe Jonas, Vincent Poitout, Rohit N. Kulkarni, and Franck Mauvais-Jarvis

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Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes, Nora M. Kochupurakkal, Annie J. Kruger, Sudipta Tripathi, Bing Zhu, La Tonya Adams, Daniel B. Rainbow, Aldo A. Rossini, Dale L. Greiner, Mohamed H. Sayegh, Linda S. Wicker, and Indira Guleria

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Coincident pre-diabetes is associated with dysregulated cytokine responses in pulmonary tuberculosis, Nathella Pavan Kumar, Vaithilingam V. Banurekha, Dina Nair, Rathinam Sridhar, Hardy Kornfeld, Thomas B. Nutman, and Subash Babu

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Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors, Govind Kunduri, Changqing Yuan, Velayoudame Parthibane, Katherine M. Nyswaner, Ritu Kanwar, Kunio Nagashima, Steven G. Britt, Nickita Mehta, Varshika Kotu, Mindy Porterfield, Michael Tiemeyer, Patrick J. Dolph, Usha Acharya, and Jairaj K. Acharya

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The PPARgamma locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner, Scott E. LeBlanc, Qiong Wu, A. Rasim Barutcu, Hengyi Xiao, Yasuyuki Ohkawa, and Anthony N. Imbalzano

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Weight gain prevention in the school worksite setting: Results of a multi-level cluster randomized trial, Stephenie C. Lemon, Monica L. Wang, Nicole M. Wedick, Barbara Estabrook, Susan Druker, Kristin L. Schneider, Wenjun Li, and Lori Pbert

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Circulating levels of soluble MICB in infants with symptomatic primary dengue virus infections, Daniel H. Libraty, Lei Zhang, AnaMae Obcena, Job D. Brion, and Rosario Z. Capeding

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Low adiposity during early infancy is associated with a low risk for developing dengue hemorrhagic fever: a preliminary model, Daniel H. Libraty, Lei Zhang, Marcia Woda, Krisanthi Giaya, Chido Loveness Kathivu, Luz P. Acosta, Veronica Tallo, Edelwisa Segubre-Mercado, Analisa Bautista, AnaMae Obcena, Job D. Brion, and Rosario Z. Capeding

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Concurrent measurement of dynamic changes in viral load, serum enzymes, T cell subsets, and cytokines in patients with severe fever with thrombocytopenia syndrome, Jun Li, Yaping Han, Yiping Xing, Shuang Li, Lianhua Kong, Yongxiang Zhang, Lili Zhang, Ning Liu, Qian Wang, Shixia Wang, Shan Lu, and Zuhu Huang

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Whole blood gene expression and atrial fibrillation: the Framingham Heart Study, Honghuang Lin, Xiaoyan Yin, Kathryn L. Lunetta, Josee Dupuis, David D. McManus, Steven A. Lubitz, Jared W. Magnani, Roby Joehanes, Peter J. Munson, Martin G. Larson, Daniel Levy, Patrick T. Ellinor, and Emelia J. Benjamin

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Learning to rank figures within a biomedical article, Feifan Liu and Hong Yu

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Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6, Wan-Ju Liu, John S. Reece-Hoyes, Albertha J. M. Walhout, and David M. Eisenmann

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Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice, Stephen Lyle, Kathleen Hoover, Cansu Colpan, Zhiqing Zhu, Zdenka Matijasevic, and Stephen N. Jones

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Aripiprazole Decreases Irritability in 12 out of 14 Youth with Autism Spectrum Disorders, Ann E. Maloney, Eric O. Mick, and Jean A. Frazier

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Pregnancy-associated breast cancers are driven by differences in adipose stromal cells present during lactation, Jessica McCready, Lisa M. Arendt, Eugene Glover, Vandana Iyer, Jerrica L. Briendel, Stephen Lyle, Stephen P. Naber, Daniel G. Jay, and Charlotte Kuperwasser

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Genome-wide association study of proneness to anger, Eric O. Mick, James J. McGough, Curtis K. Deutsch, Jean A. Frazier, David N. Kennedy, and Robert J. Goldberg

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The hunt for protective correlates of immunity to Plasmodium falciparum malaria, Ann M. Moormann and V. Ann Stewart

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Sickle cell trait is not associated with endemic Burkitt lymphoma: an ethnicity and malaria endemicity-matched case-control study suggests factors controlling EBV may serve as a predictive biomarker for this pediatric cancer, David H. Mulama, Jeffrey A. Bailey, Joslyn Foley, Kiprotich Chelimo, Collins Ouma, Walter G.Z.O. Jura, Juliana A. Otieno, John M. Vulule, and Ann M. Moormann

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Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism, Ji Young Mun, Michael J. Previs, Hope Y. Yu, James Gulick, Larry S. Tobacman, Samantha Beck Previs, Jeffrey Robbins, David M. Warshaw, and Roger Craig

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IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis, Kimberly A. Negrin, Rachel J. Roth Flach, Marina T. DiStefano, Anouch Matevossian, Randall H. Friedline, Dae Young Jung, Jason K. Kim, and Michael P. Czech

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Sex differences in clinical characteristics, hospital management practices, and in-hospital outcomes in patients hospitalized in a vietnamese hospital with a first acute myocardial infarction, Hoa L. Nguyen, Duc Anh Ha, Dat Tuan Phan, Quang Ngoc Nguyen, Viet Lan Nguyen, Nguyen Hanh Nguyen, Ha Nguyen, and Robert J. Goldberg

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Prevalence of comorbidities and their impact on hospital management and short-term outcomes in Vietnamese patients hospitalized with a first acute myocardial infarction, Hoa L. Nguyen, Quang Ngoc Nguyen, Duc Anh Ha, Dat Tuan Phan, Nguyen Hanh Nguyen, and Robert J. Goldberg

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Virulent and avirulent strains of Toxoplasma gondii which differ in their glycosylphosphatidylinositol content induce similar biological functions in macrophages, Sebastian Niehus, Terry K. Smith, Nahid Azzouz, Marco A. Campos, Jean-Francois Dubremetz, Ricardo T. Gazzinelli, Ralph T. Schwarz, and Francoise Debierre -Grockiego

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The Effects of Vitamin D supplementation on Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Children and Adolescents with Vitamin D Deficiency and Either Type 1 or Type 2 Diabetes Mellitus, Benjamin U. Nwosu and Louise Maranda

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The Vitamin D Status of Prison Inmates, Benjamin U. Nwosu, Louise Maranda, Rosalie Berry, Barbara Colocino, Carlos D. Flores, Kerry Folkman, Thomas Groblewski, and Patricia Ruze

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An anti-inflammatory diet as treatment for inflammatory bowel disease: a case series report, Barbara C. Olendzki, Taryn Silverstein, Gioia M. Persuitte, Yunsheng Ma, Katherine Baldwin, and David R. Cave

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Design characteristics of the CORRONA CERTAIN study: a comparative effectiveness study of biologic agents for rheumatoid arthritis patients, Dimitrios A. Pappas, Joel M. Kremer, George W. Reed, Jeffrey D. Greenberg, and Jeffrey R. Curtis

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Institution specific risk factors for 30 day readmission at a community hospital: a retrospective observational study, Lee Park, Danielle Andrade, Andrew Mastey, James Sun, and LeRoi S. Hicks

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Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens, Christian M. Parobek, Jeffrey A. Bailey, Nicholas J. Hathaway, Duong Socheat, William O. Rogers, and Jonathan J. Juliano

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An unstable Th epitope of P. falciparum fosters central memory T cells and anti-CS antibody responses, Carlos A. Parra-Lopez, David Bernal -Estevez, Luis Eduardo Eduardo Vargas, Carolina Pulido -Calixto, Luz Mary Salazar, J. Mauricio Calvo-Calle, and Lawrence J. Stern

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Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs, Ilona Patursky-Polischuk, Judith Kasir, Rachel Miloslavski, Zvi Hayouka, Mirit Hausner-Hanochi, Miri Stolovich-Rain, Pinchas Tsukerman, Moshe Biton, Rajini R. Mudhasani, Stephen N. Jones, and Oded Meyuhas

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Knowledge and awareness of HPV vaccine and acceptability to vaccinate in sub-Saharan Africa: a systematic review, Stacey Perlman, Richard G. Wamai, Paul A. Bain, Thomas Welty, Edith Welty, and Javier Gordon Ogembo

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Computational design of the affinity and specificity of a therapeutic T cell receptor, Brian G. Pierce, Lance M. Hellman, Moushumi Hossain, Nishant K. Singh, Craig W. Vander Kooi, Zhiping Weng, and Brian M. Baker

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Modeling T cell receptor recognition of CD1-lipid and MR1-metabolite complexes, Brian G. Pierce, Thom Vreven, and Zhiping Weng

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The impact of protocol assignment for older adolescents with Hodgkin lymphoma, Richard S. Pieters, Henry Wagner, Stephen P. Baker, Karen Morano, Kenneth Ulin, Maria Giulia Cicchetti, Maryann Bishop-Jodoin, and Thomas J. Fitzgerald

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On the prospect of identifying adaptive loci in recently bottlenecked populations, Yu-Ping Poh, Vera S. Domingues, Hopi E. Hoekstra, and Jeffrey D. Jensen

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Diversity and expression of microRNAs in the filarial parasite, Brugia malayi, Catherine B. Poole, Weifeng Gu, Sanjay Kumar, Jingmin Jin, Paul J. Davis, David Bauche, and Larry A. McReynolds

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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase beta and regulates complex V activity, Motiur Rahman, Niraj K. Nirala, Alka Singh, Lihua Julie Zhu, Kaori Taguchi, Takeshi Bamba, Eiichiro Fukusaki, Leslie M. Shaw, David G. Lambright, Jairaj K. Acharya, and Usha R. Acharya

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Smurf2 regulates hematopoietic stem cell self-renewal and aging, Charusheila Ramkumar, Yahui Kong, Sally E. Trabucco, Rachel M. Gerstein, and Hong Zhang

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Structure-centered portal for child psychiatry research, Pallavi Rane, Christian Haselgrove, Steven M. Hodge, Jean A. Frazier, and David N. Kennedy

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Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cells, Raghavendra Pralhada Rao, Luana Scheffer, Sargur M. Srideshikan, Velayoudame Parthibane, Teresa Kosakowska-Cholody, M. Athar Masood, Kunio Nagashima, Prabhakar Gudla, Stephen Lockett, Usha Acharya, and Jairaj K. Acharya

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GRAIDs: a framework for closing the gap in the availability of health promotion programs and interventions for people with disabilities, James H. Rimmer, Kerri A. Vanderbom, Linda G. Bandini, Charles E. Drum, Karen Luken, Yolanda Suarez-Balcazar, and Ian D. Graham

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A Virtual World Versus Face-to-Face Intervention Format to Promote Diabetes Self-Management Among African American Women: A Pilot Randomized Clinical Trial, Milagros C. Rosal, Robin Heyden, Roanne Mejilla, Roberta Capelson, Karen A. Chalmers, Maria Rizzo DePaoli, Chetty Veerappa, and John M. Wiecha

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iNKT cell production of GM-CSF controls Mycobacterium tuberculosis, Alissa C. Rothchild, Pushpa Jayaraman, Claudio Nunes-Alves, and Samuel M. Behar

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A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype, Ryan W. Serra, Minggang Fang, Sung Mi Park, Lloyd Hutchinson, and Michael R. Green

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Sensory neuron development in mouse coccygeal vertebrae and its relationship to tail biopsies for genotyping, Jerald Silverman and Gregory M. Hendricks

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A separable domain of the p150 subunit of human Chromatin Assembly Factor-1 promotes protein and chromosome associations with nucleoli, Corey L. Smith, Timothy D. Matheson, Daniel J. Trombly, Xiaoming Sun, Eric Campeau, Xuemei Han, John R. Yates III, and Paul D. Kaufman