This collection showcases the journal articles and other publications authored by researchers in the Nickerson Lab in the Department of Cell and Developmental Biology at the University of Massachusetts Medical School.

Submissions from 2014

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Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin, L. Damiano, K. M. Stewart, Nathalie Cohet, J. K. Mouw, J. N. Lakins, J. Debnath, D. Reisman, Jeffrey A. Nickerson, Anthony N. Imbalzano, and V. M. Weaver (Oncogene)

Submissions from 2013

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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics, Desiree M. Baron, Laura J. Kaushansky, Catherine L. Ward, Reddy Ranjith Kumar Sama, Ru-ju Chian, Kristin J. Boggio, Alexandre J. C. Quaresma, Jeffrey A. Nickerson, and Daryl A. Bosco (Molecular neurodegeneration)

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BRG1, a SWI/SNF chromatin remodeling enzyme ATPase, is required for maintenance of nuclear shape and integrity, Anthony N. Imbalzano, Karen M. Imbalzano, and Jeffrey A. Nickerson (Communicative and integrative biology)

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Nuclear Shape Changes Are Induced by Knockdown of the SWI/SNF ATPase BRG1 and Are Independent of Cytoskeletal Connections, Karen M. Imbalzano, Nathalie Cohet, Qiong Wu, Jean M. Underwood, Anthony N. Imbalzano, and Jeffrey A. Nickerson (PloS one)

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Modulation of Nuclear Shape by Substrate Rigidity, David B. Lovett, Nandini Shekhar, Jeffrey A. Nickerson, Kyle J. Roux, and Tanmay P. Lele (Cellular and Molecular Bioengineering)

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Regulation of mRNA Export by the PI3 kinase / AKT Signal Transduction Pathway, Alexandre Jose Christino Quaresma, Rachel Sievert, and Jeffrey A. Nickerson (Molecular biology of the cell)

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Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice, Giovane G. Tortelote, Jose Manuel Hernandez, Alexandre J. C. Quaresma, Jeffrey A. Nickerson, Anthony N. Imbalzano, and Jaime A. Rivera-Perez (Developmental biology)

Submissions from 2011

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The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing, Luis G. Morello, Patricia P. Coltri, Alexandre J.C. Quaresma, Fernando M. Simabuco, Tereza C.L. Sila, Guramrit Singh, Jeffrey A. Nickerson, Carla C. Oliveira, Melissa J. Moore, and Nilson I. T. Zanchin (PloS one)

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Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression, Shirwin M. Pockwinse, Krishna P. Kota, Alexandre J. C. Quaresma, Anthony N. Imbalzano, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jeffrey A. Nickerson (Journal of cellular physiology)

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An architectural genetic and epigenetic perspective, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Sayyed K. Zaidi, Jeffrey A. Nickerson, Martin A. Montecino, and Daniel W. Young (Integrative biology : quantitative biosciences from nano to macro)

Submissions from 2010

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SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells, Nathalie Cohet, Kathleen M. Stewart, Rajini R. Mudhasani, Ananthi J. Asirvatham, Chandrashekara Mallappa, Karen M. Imbalzano, Valerie M. Weaver, Anthony N. Imbalzano, and Jeffrey A. Nickerson (Journal of cellular physiology)

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Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1, Hira Lal Goel, Jean M. Underwood, Jeffrey A. Nickerson, Chung-Cheng Hsieh, and Lucia R. Languino (Journal of cellular physiology)

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Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments, Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Sayyed K. Zaidi, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein (Critical reviews in eukaryotic gene expression)

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Subnuclear localization and intranuclear trafficking of transcription factors, Sayyed K. Zaidi, Ricardo F. Medina, Shirwin M. Pockwinse, Rachit Bakshi, Krishna P. Kota, Syed A. Ali, Daniel W. Young, Jeffrey A. Nickerson, Amjad Javed, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Methods in molecular biology (Clifton, N.J.))

Submissions from 2009

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Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture, Karen M. Imbalzano, Iva Tatarkova, Anthony N. Imbalzano, and Jeffrey A. Nickerson (Cancer cell international)

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The biochemistry of RNA metabolism studied in situ, Jeffrey A. Nickerson (RNA biology)

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Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression, Jitesh Pratap, Karen M. Imbalzano, Jean. M. Underwood, Nathalie Cohet, Karthiga Devi Gokul, Jacqueline Akech, Andre J. Van Wijnen, Janet L. Stein, Anthony N. Imbalzano, Jeffrey A. Nickerson, Jane B. Lian, and Gary S. Stein (Cancer research)

Submissions from 2008

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Binding of ATP to UAP56 is necessary for mRNA export, Krishna P. Kota, Stefan R. Wagner, Elvira Huerta, Jean. M. Underwood, and Jeffrey A. Nickerson (Journal of cell science)

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In situ nuclear organization of regulatory machinery, Shirwin M. Pockwinse, Sayyed K. Zaidi, Ricardo F. Medina, Rachit Bakshi, Krishna P. Kota, Syed A. Ali, Daniel W. Young, Jeffrey A. Nickerson, Amjad Javed, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Methods in molecular biology (Clifton, N.J.))

Submissions from 2007

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Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2, Daniel W. Young, Mohammad Q. Hassan, Jitesh Pratap, Mario Galindo, Sayyed K. Zaidi, Suk Hee Lee, Xiaoqing Yang, Ronglin Xie, Amjad Javed, Jean M. Underwood, Paul S. Furcinitti, Anthony N. Imbalzano, Sheldon Penman, Jeffrey A. Nickerson, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Nature)

Submissions from 2006

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Methods for measuring rates of protein binding to insoluble scaffolds in living cells: histone H1-chromatin interactions, Tanmay Lele, Stefan R. Wagner, Jeffrey A. Nickerson, and Donald E. Ingber (Journal of cellular biochemistry)

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The ultrastructure of MCF-10A acini, Jean. M. Underwood, Karen M. Imbalzano, Valerie M. Weaver, Andrew H. Fischer, Anthony N. Imbalzano, and Jeffrey A. Nickerson (Journal of cellular physiology)

Submissions from 2005

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Pulse energy dependence of subcellular dissection by femtosecond laser pulses, A. Heisterkamp, I. Z. Maxwell, E. Mazur, Jean M. Underwood, Jeffrey A. Nickerson, S. Kumar, and Donald E. Ingber (Optics express)

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PTEN enters the nucleus by diffusion, Fenghua Liu, Stefan R. Wagner, Robert B. Campbell, Jeffrey A. Nickerson, Celia A. Schiffer, and Alonzo H. Ross (Journal of cellular biochemistry)

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Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin, Susan McCracken, Dasa Longman, Edyta Marcon, Peter Moens, Michael Downey, Jeffrey A. Nickerson, Rolf Jessberger, Andrew Wilde, Javier F. Caceres, Andrew Emili, and Benjamin J. Blencowe (The Journal of biological chemistry)

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Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2, Shirwin M. Pockwinse, Arun Rajgopal, Daniel W. Young, Khwaja A. Mujeeb, Jeffrey A. Nickerson, Amjad Javed, Sambra D. Redick, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Stephen J. Doxsey (Journal of cellular physiology)

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Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes, Diana Vradii, Stefan Wagner, Diem N. Doan, Jeffrey A. Nickerson, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, Anthony N. Imbalzano, and Gary S. Stein (Journal of cellular physiology)

Submissions from 2004

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Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme, David A. Hill, Simion I. Chiosea, Saha Jamaluddin, Kanaklata Roy, Andrew H. Fischer, Douglas D. Boyd, Jeffrey A. Nickerson, and Anthony N. Imbalzano (Journal of cell science)

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In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160, Stefan Wagner, Simion I. Chiosea, Mariya P. Ivshina, and Jeffrey A. Nickerson (The Journal of cell biology)

Submissions from 2003

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The spatial targeting and nuclear matrix binding domains of SRm160, Stefan Wagner, Simion I. Chiosea, and Jeffrey A. Nickerson (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 2002

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Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins, Karina Barseguian, Bart Lutterbach, Scott W. Hiebert, Jeffrey A. Nickerson, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 2001

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Experimental observations of a nuclear matrix, Jeffrey A. Nickerson (Journal of cell science)

Submissions from 1998

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Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains, Congmei Zeng, Sandra Marie McNeil, Shirwin M. Pockwinse, Jeffrey A. Nickerson, Lindsay S. Shopland, Jeanne B. Lawrence, Sheldon Penman, Scott W. Hiebert, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 1997

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The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus, Jeffrey A. Nickerson, Gabriela Krockmalnic, Katherine M. Wan, and Sheldon Penman (Proceedings of the National Academy of Sciences of the United States of America)

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Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold, Shirwin M. Pockwinse, Gabriela Krockmalnic, Stephen J. Doxsey, Jeffrey A. Nickerson, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Sheldon Penman (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 1995

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The nuclear matrix protein NMP-1 is the transcription factor YY1, Bo Guo, Paul R. Odgren, Andre J. Van Wijnen, Thomas J. Last, Jeffrey A. Nickerson, Sheldon Penman, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)