Title

Glial control of synaptogenesis

UMMS Affiliation

Department of Neurobiology

Date

2-11-2005

Document Type

Article

Medical Subject Headings

Animals; Cell Communication; Cell Differentiation; Central Nervous System; Growth Cones; Humans; Neuroglia; Neuronal Plasticity; Synapses; Thrombospondins

Disciplines

Neuroscience and Neurobiology

Abstract

Though all communication between neurons occurs through synapses, we know surprisingly little about the mechanisms inducing their formation. In this issue of Cell, Barres and colleagues (Christopherson et al., 2005) demonstrate that glial-derived thrombospondins and additional soluble glial-secreted factors regulate synapse assembly and functional maturation.

Rights and Permissions

Citation: Cell. 2005 Feb 11;120(3):292-3. Link to article on publisher's site

Related Resources

Link to Article in PubMed