Title
Glial control of synaptogenesis
UMMS Affiliation
Department of Neurobiology
Date
2-11-2005
Document Type
Article
Medical Subject Headings
Animals; Cell Communication; Cell Differentiation; Central Nervous System; Growth Cones; Humans; Neuroglia; Neuronal Plasticity; Synapses; Thrombospondins
Disciplines
Neuroscience and Neurobiology
Abstract
Though all communication between neurons occurs through synapses, we know surprisingly little about the mechanisms inducing their formation. In this issue of Cell, Barres and colleagues (Christopherson et al., 2005) demonstrate that glial-derived thrombospondins and additional soluble glial-secreted factors regulate synapse assembly and functional maturation.
Rights and Permissions
Citation: Cell. 2005 Feb 11;120(3):292-3. Link to article on publisher's site
Related Resources
COinS