Glial control of synaptogenesis
Department of Neurobiology
Medical Subject Headings
Animals; Cell Communication; Cell Differentiation; Central Nervous System; Growth Cones; Humans; Neuroglia; Neuronal Plasticity; Synapses; Thrombospondins
Neuroscience and Neurobiology
Though all communication between neurons occurs through synapses, we know surprisingly little about the mechanisms inducing their formation. In this issue of Cell, Barres and colleagues (Christopherson et al., 2005) demonstrate that glial-derived thrombospondins and additional soluble glial-secreted factors regulate synapse assembly and functional maturation.
Rights and Permissions
Citation: Cell. 2005 Feb 11;120(3):292-3. Link to article on publisher's site