Studying circadian rhythms in Drosophila melanogaster

UMMS Affiliation

Department of Neurobiology; Emery Lab



Document Type



Neuroscience and Neurobiology


Circadian rhythms have a profound influence on most bodily functions: from metabolism to complex behaviors. They ensure that all these biological processes are optimized with the time-of-day. They are generated by endogenous molecular oscillators that have a period that closely, but not exactly, matches day length. These molecular clocks are synchronized by environmental cycles such as light intensity and temperature. Drosophila melanogaster has been a model organism of choice to understand genetically, molecularly and at the level of neural circuits how circadian rhythms are generated, how they are synchronized by environmental cues, and how they drive behavioral cycles such as locomotor rhythms. This review will cover a wide range of techniques that have been instrumental to our understanding of Drosophila circadian rhythms, and that are essential for current and future research.

Rights and Permissions

Citation: Methods. 2014 Jun 15;68(1):140-50. doi: 10.1016/j.ymeth.2014.01.001. Epub 2014 Jan 9. Link to article on publisher's site

Related Resources

Link to Article in PubMed


Behavior, Circadian rhythms, Clock neurons, Drosophila

PubMed ID