Title

Orphan nuclear receptors control neuronal remodeling during fly metamorphosis

UMMS Affiliation

Department of Neurobiology

Date

1-1-2011

Document Type

Article

Medical Subject Headings

Animals; Brain; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Metamorphosis, Biological; Models, Neurological; Neurons; Orphan Nuclear Receptors; Receptors, Steroid; Transcription Factors

Disciplines

Neuroscience and Neurobiology

Abstract

Pruning of excess branches is essential for the maturation of developing neuronal circuits. Cross-talk between TGF-β signaling and two antagonistic orphan nuclear receptors governs the pruning of larval γ neurons in the Drosophila pupa.

Rights and Permissions

Citation: Nat Neurosci. 2011 Jan;14(1):6-7. Link to article on publisher's site

Related Resources

Link to Article in PubMed