Title
Orphan nuclear receptors control neuronal remodeling during fly metamorphosis
UMMS Affiliation
Department of Neurobiology
Date
1-1-2011
Document Type
Article
Medical Subject Headings
Animals; Brain; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Metamorphosis, Biological; Models, Neurological; Neurons; Orphan Nuclear Receptors; Receptors, Steroid; Transcription Factors
Disciplines
Neuroscience and Neurobiology
Abstract
Pruning of excess branches is essential for the maturation of developing neuronal circuits. Cross-talk between TGF-β signaling and two antagonistic orphan nuclear receptors governs the pruning of larval γ neurons in the Drosophila pupa.
Rights and Permissions
Citation: Nat Neurosci. 2011 Jan;14(1):6-7. Link to article on publisher's site
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