This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Department of Neurology.

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Volume 5, Issue 1 (2013) of Neurological Bulletin is now available online.

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Publications from 2003

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Emerging therapies for acute ischemic stroke: new therapies on trial, Marc Fisher and Thomas G. Brott

Magnetic Resonance Imaging in Stroke, Marc Fisher, Stephen Davis, and Steven Warach

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Combination Therapies, Restorative Therapies and Future Directions, Marc Fisher and Majaz Moonis

Neurovascular Disorders, Marc Fisher, E. Orberk, and M. Ramzan

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New perspectives on developing acute stroke therapy, Marc Fisher and Rajiv Ratan

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The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats, Tibo Gerriets, Fuhai Li, Matthew D. Silva, Xiangjun Meng, Mathew E. Brevard, Christopher H. Sotak, and Marc Fisher

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Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: adverse effects of hypothalamic damage and strategies for its avoidance, Tibo Gerriets, Erwin Stolz, Maureen Walberer, Manfred Kaps, Georg Bachmann, and Marc Fisher

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Neuroprotective effects of a new synthetic peptide, CMX-9236, in in vitro and in vivo models of cerebral ischemia, Victor E. Shashoua, David S. Adams, Anne Boyer-Boiteau, Ann Cornell-Bell, Fuhai Li, and Marc Fisher

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Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging, Qiang Shen, Xiangjun Meng, Marc Fisher, Christopher H. Sotak, and Timothy Q. Duong

Publications from 2002

Hat size, brain size, intelligence, and dementia: what morphometry can tell us about brain function and disease, David A. Drachman

The treatment of Alzheimer's disease: where have we been, and where are we going, David A. Drachman

Dementia, butterfly ballots, and voter competence, Victor W. Henderson and David A. Drachman

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Considering the role of heparin and low-molecular-weight heparins in acute ischemic stroke, Majaz Moonis and Marc Fisher

Aging and Dementia: principles, evaluation and diagnosis, Sudha Seshadri and David A. Drachman

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Separating changes in the intra- and extracellular water apparent diffusion coefficient following focal cerebral ischemia in the rat brain, Matthew D. Silva, Tsuyoshi Omae, Karl G. Helmer, Fuhai Li, Marc Fisher, and Christopher H. Sotak

Publications from 2001

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Practice Parameters: Diagnosis, Treatment, and Early Detection of Dementia, David A. Drachman

Stroke Therapy (2nd ed.), Marc Fisher

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Regional variations in the apparent diffusion coefficient and the intracellular distribution of water in rat brain during acute focal ischemia, Kai-Feng Liu, Fuhai Li, Turgut Tatlisumak, Julio H. Garcia, Christopher H. Sotak, Marc Fisher, and Joseph D. Fenstermacher

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Neural precursor cells form rudimentary tissue-like structures in a rotating-wall vessel bioreactor, Hoi Pang Low, Todd M. Savarese, and William J. Schwartz

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Towards the reconstruction of central nervous system white matter using neural precursor cells, Masato Mitome, Hoi Pang Low, Anthony van den Pol, John J. Nunnari, Merrill K. Wolf, Susan Billings-Gagliardi, and William J. Schwartz

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Imaging of acute stroke, Majaz Moonis and Marc Fisher

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Ataxia associated with Hashimoto's disease: progressive non-familial adult onset cerebellar degeneration with autoimmune thyroiditis, Magdy H. Selim and David A. Drachman

Postmenopausal estrogen replacement therapy and the risk of Alzheimer disease, Sudha Seshadri, Gwen L. Zornberg, Laura E. Derby, Marian W. Myers, Hershel Jick, and David A. Drachman

Psychological features in persons at risk for familial Alzheimer's disease, Joan M. Swearer, Brian F. O'Donnell, Michael Parker, Kevin J. Kane, and David A. Drachman

Publications from 2000

Alzheimer's disease: what is it, how many people have it, and why do we need to know, Marilyn S. Albert and David A. Drachman

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Patients with acute stroke: recent developments in neuroimaging, Pierre C. Combremont and Marc Fisher

Occam's razor, geriatric syndromes, and the dizzy patient, David A. Drachman

Current Review of Cerebrovascular Disease (4th ed.), Marc Fisher and Julien Bogousslavsky

Prevention of Ischemic Stroke, Marc Fisher and Cesare Fieschi

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An overview of acute stroke therapy: past, present, and future, Marc Fisher and Wolf-Rudiger Schabitz

Statins and the risk of dementia, Hershel Jick, Gwen L. Zornberg, Susan S. Jick, Sudha Seshadri, and David A. Drachman

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Secondary decline in apparent diffusion coefficient and neurological outcomes after a short period of focal brain ischemia in rats, Fuhai Li, Matthew D. Silva, Kai-Feng Liu, Karl G. Helmer, Tsuyoshi Omae, Joseph D. Fenstermacher, Christopher H. Sotak, and Marc Fisher

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Temporal evolution of ischemic injury evaluated with diffusion-, perfusion-, and T2-weighted MRI, Fuhai Li, Matthew D. Silva, Christopher H. Sotak, and Marc Fisher

Familial Alzheimer's disease: site of mutation influences clinical phenotype, Carol F. Lippa, Joan M. Swearer, Kevin J. Kane, David Nochlin, Thomas D. Bird, Bernardino Ghetti, Linda Nee, Peter H. St. George-Hyslop, Daniel A. Pollen, and David A. Drachman

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Broad-spectrum cation channel inhibition by LOE 908 MS reduces infarct volume in vivo and postmortem in focal cerebral ischemia in the rat, Turgut Tatlisumak, Richard A.D. Carano, Kentaro Takano, Michael R. Meiler, Fuhai Li, Christopher H. Sotak, Dietrich Arndts, Uwe Pschorn, and Marc Fisher

Publications from 1999

A 69-year-old man with chronic dizziness, David A. Drachman

Risk factors for seizure-related motor vehicle crashes in patients with epilepsy, David A. Drachman

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 12-1999. A 67-year-old man with three years of dementia, David A. Drachman and Kathy L. Newell

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Antithrombotic and thrombolytic therapy for ischemic stroke, Marc Fisher

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Applications of diffusion-perfusion magnetic resonance imaging in acute ischemic stroke, Marc Fisher and Gregory W. Albers

Current Review of Cerebrovascular Disease (3rd ed.), Marc Fisher and Julien Bogousslavsky

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Pharmacological approaches to stroke recovery, Marc Fisher and Seth P. Finklestein

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Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats, Fuhai Li, Sam S. Han, Turgut Tatlisumak, Kai-Feng Liu, Julio H. Garcia, Christopher H. Sotak, and Marc Fisher

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Spontaneous hyperthermia and its mechanism in the intraluminal suture middle cerebral artery occlusion model of rats, Fuhai Li, Tsuyoshi Omae, and Marc Fisher

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Myocardial infarction, seizure and an abnormal head CT scan, Nithianandam Selvaraj, David A. Drachman, Paula D. Ravin, and John R. Knorr

Publications from 1998

From capitation to rhinocitation, Jeffrey D. Bernhard and David A. Drachman

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Determination of focal ischemic lesion volume in the rat brain using multispectral analysis, Richard A.D. Carano, Kentaro Takano, Karl G. Helmer, Turgut Tatlisumak, Katsumi Irie, Joseph D. Petruccelli, Marc Fisher, and Christopher H. Sotak

Degenerative Dementias, David A. Drachman and Joan M. Swearer

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The travails of neuroprotective drug development for acute ischemic stroke, Marc Fisher

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Further evolution toward effective therapy for acute ischemic stroke, Marc Fisher and Julien Bogousslavsky

Textbook of Neurology, Marc Fisher and Julien Bogousslavsky

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A new method to improve in-bore middle cerebral artery occlusion in rats: demonstration with diffusion- and perfusion-weighted imaging, Fuhai Li, Sam S. Han, Turgut Tatlisumak, Richard A.D. Carano, Katsumi Irie, Christopher H. Sotak, and Marc Fisher

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Amastigote surface proteins of Trypanosoma cruzi are targets for CD8+ CTL, Hoi Pang Low, Maria A. M. Santos, Benjamin Wizel, and Rick L. Tarleton

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Efficacy of intra-arterial and intravenous prourokinase in an embolic stroke model evaluated by diffusion-perfusion magnetic resonance imaging, Kentaro Takano, Richard A.D. Carano, Turgut Tatlisumak, Michael R. Meiler, Christopher H. Sotak, H. D. Kleinert, and Marc Fisher

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A novel endothelin antagonist, A-127722, attenuates ischemic lesion size in rats with temporary middle cerebral artery occlusion: a diffusion and perfusion MRI study, Turgut Tatlisumak, Richard A.D. Carano, Kentaro Takano, Terry J. Opgenorth, Christopher H. Sotak, and Marc Fisher

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Delayed treatment with an adenosine kinase inhibitor, GP683, attenuates infarct size in rats with temporary middle cerebral artery occlusion, Turgut Tatlisumak, Kentaro Takano, Richard A.D. Carano, Leonard P. Miller, Alan C. Foster, and Marc Fisher

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A glycine site antagonist, ZD9379, reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion, Turgut Tatlisumak, Kentaro Takano, Michael R. Meiler, and Marc Fisher

Publications from 1997

Aging and the brain: a new frontier, David A. Drachman

Treatment of Alzheimer's disease -- searching for a breakthrough, settling for less, David A. Drachman and Paul Leber

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Carvedilol inhibits aortic lipid deposition in the hypercholesterolemic rat, Giora Z. Feuerstein, Marc Fisher, John J. Nunnari, and Robert R. Ruffolo Jr.

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Characterizing the target of acute stroke therapy, Marc Fisher

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Delayed triphenyltetrazolium chloride staining remains useful for evaluating cerebral infarct volume in a rat stroke model, Fuhai Li, Katsumi Irie, M. Sawkat Anwer, and Marc Fisher

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Molecular cloning of the gene encoding the 83 kDa amastigote surface protein and its identification as a member of the Trypanosoma cruzi sialidase superfamily, Hoi Pang Low and Rick L. Tarleton

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Acute ischemic stroke therapy. A clinical overview, M. Zulkuf Onal and Marc Fisher

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Synergistic effects of citicoline and MK-801 in temporary experimental focal ischemia in rats, M. Zulkuf Onal, Fuhai Li, Turgut Tatlisumak, Kenneth W. Locke, Bobby W. Sandage Jr., and Marc Fisher

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Caretaker Obstreperous Behavior Rating Scale, Joan M. Swearer and David A. Drachman

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Reproducibility and reliability of middle cerebral artery occlusion using a silicone-coated suture (Koizumi) in rats, Kentaro Takano, Turgut Tatlisumak, Andreas G. Bergmann, Daniel G. Gibson III, and Marc Fisher

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Glycine site antagonist attenuates infarct size in experimental focal ischemia. Postmortem and diffusion mapping studies, Kentaro Takano, Turgut Tatlisumak, James E. Formato, Richard A.D. Carano, Andreas G. Bergmann, Linda M. Pullan, Thomas M. Bare, Christopher H. Sotak, and Marc Fisher

Publications from 1996

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Acute and atypical presentations of syringomyelia, Ursula E. Anwer and Marc Fisher

Screening for dementia: Cognitive Assessment Screening Test (CAST), David A. Drachman and Joan M. Swearer

The cognitive assessment screening test (CAST) for dementia, David A. Drachman, Joan M. Swearer, Kevin J. Kane, Diane L. Osgood, Colleen O'Toole, and Majaz Moonis

Current Review of Cerebrovascular Disease (2nd ed.), Marc Fisher and Julien Bogousslavsky

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Severe transient hypoglycemia causes reversible change in the apparent diffusion coefficient of water, Yasuhiro Hasegawa, James E. Formato, Lawrence L. Latour, Jorge A. Gutierrez, Kai-Feng Liu, Julio H. Garcia, Christopher H. Sotak, and Marc Fisher

Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway, Carol F. Lippa, Ann M. Saunders, Thomas W. Smith, Joan M. Swearer, David A. Drachman, Bernardino Ghetti, Linda Nee, D. Pulaski-Salo, Dennis Dickson, Yves Robitaille, C. Bergeron, Barbara Crain, Merrill D. Benson, Martin R. Farlow, Bradley T. Hyman, Peter H. St. George-Hyslop, Allen D. Roses, and Daniel A. Pollen

Foreign Accent Syndrome Following a Closed Head Injury: Perfusion Deficit on Single Photon Emission Tomography with Normal Magnetic Resonance Imaging, Majaz Moonis, Joan M. Swearer, S. E. Blumstein, K. Kurowski, Robert Licho, P. Kramer, Ann L. Mitchell, Diane L. Osgood, and David A. Drachman

Medical therapy for ischemic stroke, Brian Silver, Johannes Weber, and Marc Fisher

Predicting Aberrant Behavior in Alzheimer's Disease, Joan M. Swearer, Nancy E. Hoople, Kevin J. Kane, and David A. Drachman

Rate of progression in familial Alzheimer's disease, Joan M. Swearer, Brian F. O'Donnell, Susan M. Ingram, and David A. Drachman

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The role of spreading depression in focal ischemia evaluated by diffusion mapping, Kentaro Takano, Lawrence L. Latour, James E. Formato, Richard A.D. Carano, Karl G. Helmer, Yasuhiro Hasegawa, Christopher H. Sotak, and Marc Fisher

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Hematologic disorders associated with ischemic stroke, Turgut Tatlisumak and Marc Fisher

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Effect of basic fibroblast growth factor on experimental focal ischemia studied by diffusion-weighted and perfusion imaging, Turgut Tatlisumak, Kentaro Takano, Richard A.D. Carano, and Marc Fisher

Publications from 1995

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Acute stroke treatment trials in the United States. Rethinking strategies for success, Robert J. Adams, Marc Fisher, Anthony J. Furlan, and Gregory del Zoppo

Diagnosis and evaluation of dementia, Jody Corey-Bloom, Leon J. Thal, Douglas R. Galasko, Marshall F. Folstein, David A. Drachman, Murray A. Raskind, and Douglas J. Lanska

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Diffusion and perfusion imaging for acute stroke, Marc Fisher

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Potentially effective therapies for acute ischemic stroke, Marc Fisher

Stroke Therapy, Marc Fisher

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Delayed treatment with intravenous basic fibroblast growth factor reduces infarct size following permanent focal cerebral ischemia in rats, Marc Fisher, Mary-Ellen Meadows, Tuyen Do, Jens Weise, Vladimir Trubetskoy, Marc Charette, and Seth P. Finklestein

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ECASS: lessons for future thrombolytic stroke trials. European Cooperative Acute Stroke Study, Marc Fisher, Michael S. Pessin, and Anthony J. Furian

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Spreading waves of a reduced diffusion coefficient of water in normal and ischemic rat brain, Yasuhiro Hasegawa, Lawrence L. Latour, James E. Formato, Christopher H. Sotak, and Marc Fisher

Role of the dorsomedial nucleus of the thalamus in Alzheimer's disease, James F. Paskavitz, Carol F. Lippa, James E. Hamos, D. Pulaski-Salo, and David A. Drachman

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Multislice diffusion mapping for 3-D evolution of cerebral ischemia in a rat stroke model, W. Reith, Yasuhiro Hasegawa, Lawrence L. Latour, Bernard J. Dardzinski, Christopher H. Sotak, and Marc Fisher

Apolipoprotein E epsilon 4 allele and the lifetime risk of Alzheimer's disease. What physicians know, and what they should know, Sudha Seshadri, David A. Drachman, and Carol F. Lippa

Publications from 1994

Effects of a novel NMDA receptor antagonist on experimental stroke quantitatively assessed by spectral EEG and infarct volume, Ronald A. Cohen, Yasuhiro Hasegawa, and Marc Fisher

Dizziness, David A. Drachman

If we live long enough, will we all be demented, David A. Drachman

Neurological Evaluation in the Elderly Patient, David A. Drachman, Randall R. Long, and Joan M. Swearer

Clinical Atlas of Cerebrovascular Disorders, Marc Fisher

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Prophylactic neuroprotection for cerebral ischemia, Marc Fisher, Saran Jonas, and Ralph L. Sacco

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The competitive NMDA antagonist MDL-100,453 reduces infarct size after experimental stroke, Yasuhiro Hasegawa, Marc Fisher, Bruce M. Baron, and Geoffrey Metcalf

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MRI diffusion mapping of reversible and irreversible ischemic injury in focal brain ischemia, Yasuhiro Hasegawa, Marc Fisher, Lawrence L. Latour, Bernard J. Dardzinski, and Christopher H. Sotak