Title

Stroke

UMMS Affiliation

Department of Neurology

Date

5-13-2008

Document Type

Article

Subjects

Age Distribution; Anticoagulants; *Cardiovascular Diseases; Coronary Care Units; Endarterectomy, Carotid; Fibrinolytic Agents; Humans; Incidence; Prognosis; Risk Factors; *Stroke

Disciplines

Neurology | Neuroscience and Neurobiology

Abstract

Stroke is the second most common cause of death and major cause of disability worldwide. Because of the ageing population, the burden will increase greatly during the next 20 years, especially in developing countries. Advances have occurred in the prevention and treatment of stroke during the past decade. For patients with acute stroke, management in a stroke care unit, intravenous tissue plasminogen activator within 3 h or aspirin within 48 h of stroke onset, and decompressive surgery for supratentorial malignant hemispheric cerebral infarction are interventions of proven benefit; several other interventions are being assessed. Proven secondary prevention strategies are warfarin for patients with atrial fibrillation, endarterectomy for symptomatic carotid stenosis, antiplatelet agents, and cholesterol reduction. The most important intervention is the management of patients in stroke care units because these provide a framework within which further study might be undertaken. These advances have exposed a worldwide shortage of stroke health-care workers, especially in developing countries.

Rights and Permissions

Citation: Lancet. 2008 May 10;371(9624):1612-23. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

18468545