New!
Neurological Bulletin has made its debut! Volume 1, Issue 1 is now available online.
Submissions from 2008
An Approach to Neurologic Problems in the Intensive Care Unit, David A. Drachman
Commentary on "a roadmap for the prevention of dementia: the inaugural Leon Thal Symposium." Prevention of dementia: roadmap or maintenance manual, David A. Drachman
Memory and the brain: beyond intracranial phrenology, David A. Drachman
Nature or nurture: education and the trajectory of declining brain function with age and Alzheimer disease, David A. Drachman
Evaluating the Patient with Altered Consciousness in the Intensive Care Unit, Lawrence J. Hayward and David A. Drachman
Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice, Hoi Pang Low, Beatrice Greco, Yusuke Tanahashi, Judith Gallant, Stephen N. Jones, Susan Billings-Gagliardi, Lawrence D. Recht, and William J. Schwartz
Neuronal differentiation of EGF-propagated neurosphere cells after engraftment to the nucleus of the solitary tract, Masato Mitome, Hoi Pang Low, Karen M. Lora Rodriguez, Masafumi Kitamoto, Takamasa Kitamura, and William J. Schwartz
Correlation of umbilical cord blood haematopoietic stem and progenitor cell levels with birth weight: implications for a prenatal influence on cancer risk, William C. Strohsnitter, Todd M. Savarese, Hoi Pang Low, David P. Chelmow, Pagona Lagiou, Mats Lambe, Kathryn L. Edmiston, Qin Liu, Inkyung Baik, Kenneth L. Noller, Hans-Olov Adami, Dimitrios Trichopoulos, and Chung-Cheng Hsieh
Submissions from 2007
The Virtual International Stroke Trials Archive, Myzoon Ali, Philip M.W. Bath, John Curram, Stephen M. Davis, Hans-Christoph Diener, Geoffrey A. Donnan, Marc Fisher, Barbara A. Gregson, James Grotta, Werner Hacke, Michael G. Hennerici, Marc Hommel, Markku Kaste, John R. Marler, Ralph L. Sacco, Philip Teal, Nils-Gunnar Wahlgren, Steven Warach, Christopher J. Weir, and Kennedy R. Lees
Characterizing tissue fate after transient cerebral ischemia of varying duration using quantitative diffusion and perfusion imaging, Juergen F. Bardutzky, Qiang Shen, Nils Henninger, Stefan Schwab, Timothy Q. Duong, and Marc Fisher
Characterizing tissue fate after transient cerebral ischemia of varying duration using quantitative diffusion and perfusion imaging, Juergen F. Bardutzky, Qiang Shen, Nils Henninger, Stefan Schwab, Timothy Q. Duong, and Marc Fisher
Rethinking Alzheimer's disease: the role of age-related changes, David A. Drachman
Recommendations from the STAIR V meeting on acute stroke trials, technology and outcomes, Marc Fisher, Daniel F. Hanley, George Howard, Edward C. Jauch, and Steven Warach
Translational research in stroke: taking advances in the pathophysiology and treatment of stroke from the experimental setting to clinical trials, Marc Fisher and Nils Henninger
Normobaric hyperoxia delays perfusion/diffusion mismatch evolution, reduces infarct volume, and differentially affects neuronal cell death pathways after suture middle cerebral artery occlusion in rats, Nils Henninger, James P. Bouley, Julia M. Nelligan, Kenneth M. Sicard, and Marc Fisher
Stimulating circle of Willis nerve fibers preserves the diffusion-perfusion mismatch in experimental stroke, Nils Henninger and Marc Fisher
Spectacular shrinking deficit: insights from multimodal magnetic resonance imaging after embolic middle cerebral artery occlusion in Sprague-Dawley rats, Nils Henninger, Kenneth M. Sicard, and Marc Fisher
Differential recovery of behavioral status and brain function assessed with functional magnetic resonance imaging after mild traumatic brain injury in the rat, Nils Henninger, Kenneth M. Sicard, Zhixin Li, Praveen P. Kulkarni, Stephan Dutzmann, Christian Urbanek, Stefan Schwab, and Marc Fisher
Infrared laser therapy for ischemic stroke: a new treatment strategy: results of the NeuroThera Effectiveness and Safety Trial-1 (NEST-1), Yair Lampl, Justin A. Zivin, Marc Fisher, Robert A. Lew, Lennart Welin, Bjorn Dahlof, Peter Borenstein, Bjorn Andersson, Julio Perez, Cesar Caparo, Sanja Ilic, and Uri Oron
Normal breast stem cells, malignant breast stem cells, and the perinatal origin of breast cancer, Todd M. Savarese, Hoi Pang Low, Inkyung Baik, William C. Strohsnitter, and Chung-Cheng Hsieh
Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials, Sean I. Savitz and Marc Fisher
Prophylactic neuroprotection, Sean I. Savitz and Marc Fisher
Shift analysis versus dichotomization of the modified Rankin scale outcome scores in the NINDS and ECASS-II trials, Sean I. Savitz, Robert A. Lew, Erich Bluhmki, Werner Hacke, and Marc Fisher
Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia, Giles D. J. Watts, Dana Thomasova, Sheena K. Ramdeen, Erin C. Fulchiero, Sarju G. Mehta, David A. Drachman, Conrad C. Weihl, Zygmunt Jamrozik, Hubert Kwiecinski, Anna Kaminska, and Virginia E. Kimonis
Submissions from 2006
Comparison between coated vs. uncoated suture middle cerebral artery occlusion in the rat as assessed by perfusion/diffusion weighted imaging, James P. Bouley, Marc Fisher, and Nils Henninger
Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases, Suhayl Dhib-Jalbut, Douglas L. Arnold, Don W. Cleveland, Marc Fisher, Robert M. Friedlander, M. Maral Mouradian, Serge Przedborski, Bruce D. Trapp, Tony Wyss-Coray, and V. Wee Yong
Aging of the brain, entropy, and Alzheimer disease, David A. Drachman
Robert Katzman and Alzheimer's disease: an appreciation, David A. Drachman
Approaches to Cerebrovascular Disease, Marc Fisher
Identification and Treatment of Stroke Risk Factors, Marc Fisher
The ischemic penumbra: a new opportunity for neuroprotection, Marc Fisher
Imaging in Experimental Neurology, Marc Fisher, Eng H. Lo, and Michael Lev
Handbook of Experimental Neurology: Methods and Techniques in Animal Research, Marc Fisher and Turgut Tatlisumak
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations, Mark S. Forman, Ian R. Mackenzie, Nigel J. Cairns, Eric Swanson, Philip J. Boyer, David A. Drachman, Bharati S. Jhaveri, Jason H. Karlawish, Alan Pestronk, Thomas W. Smith, Pang-Hsien Tu, Giles D. J. Watts, William R. Markesbery, Charles D. Smith, and Virginia E. Kimonis
The proteasome inhibitor VELCADE reduces infarction in rat models of focal cerebral ischemia, Nils Henninger, Kenneth M. Sicard, James P. Bouley, Marc Fisher, and Nancy E. Stagliano
Comparison of ischemic lesion evolution in embolic versus mechanical middle cerebral artery occlusion in Sprague Dawley rats using diffusion and perfusion imaging, Nils Henninger, Kenneth M. Sicard, Karl F. Schmidt, Juergen F. Bardutzky, and Marc Fisher
Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea, Taichang Jang, Todd M. Savarese, Hoi Pang Low, Sunchin Kim, Hannes Vogel, David S. Lapointe, Timothy Q. Duong, N. Scott Litofsky, James M. Weimann, Alonzo H. Ross, and Lawrence D. Recht
The optic nerve: a window into diseases of the brain, Neil R. Miller and David A. Drachman
Role of heparin and low-molecular-weight heparins in the management of acute ischemic stroke, Vasantha Padma, Marc Fisher, and Majaz Moonis
Perspectives on neuroprotective stroke therapy, Wolf-Rudiger Schabitz and Marc Fisher
Differential recovery of multimodal MRI and behavior after transient focal cerebral ischemia in rats, Kenneth M. Sicard, Nils Henninger, Marc Fisher, Timothy Q. Duong, and Craig F. Ferris
Long-term changes of functional MRI-based brain function, behavioral status, and histopathology after transient focal cerebral ischemia in rats, Kenneth M. Sicard, Nils Henninger, Marc Fisher, Timothy Q. Duong, and Craig F. Ferris
Experimental stroke: ischaemic lesion volume and oedema formation differ among rat strains (a comparison between Wistar and Sprague-Dawley rats using MRI), Maureen Walberer, Erwin Stolz, Clemens Muller, C. Friedrich, Carina Rottger, F. Blaes, Manfred Kaps, Marc Fisher, Georg Bachmann, and Tibo Gerriets
Submissions from 2005
Effects of intravenous dimethyl sulfoxide on ischemia evolution in a rat permanent occlusion model, Juergen F. Bardutzky, Xiangjun Meng, James P. Bouley, Timothy Q. Duong, Rajiv Ratan, and Marc Fisher
Perfusion and diffusion imaging in acute focal cerebral ischemia: temporal vs. spatial resolution, Juergen F. Bardutzky, Qiang Shen, James P. Bouley, Christopher H. Sotak, Timothy Q. Duong, and Marc Fisher
Differences in ischemic lesion evolution in different rat strains using diffusion and perfusion imaging, Juergen F. Bardutzky, Qiang Shen, Nils Henninger, James P. Bouley, Timothy Q. Duong, and Marc Fisher
Do we have brain to spare, David A. Drachman
Developing and implementing future stroke therapies: the potential of telemedicine, Marc Fisher
Visualization of cortical spreading depression using manganese-enhanced magnetic resonance imaging, Erica C. Henning, Xiangjun Meng, Marc Fisher, and Christopher H. Sotak
HMG-CoA reductase inhibitors improve acute ischemic stroke outcome, Majaz Moonis, Kevin J. Kane, Ute Schwiderski, Bobby W. Sandage, and Marc Fisher
Myelination and long diffusion times alter diffusion-tensor-imaging contrast in myelin-deficient shiverer mice, Govind Nair, Yusuke Tanahashi, Hoi Pang Low, Susan Billings-Gagliardi, William J. Schwartz, and Timothy Q. Duong
Thrombolytic therapy for acute ischemic stroke: 3 h and beyond, Vasantha Padma, Marc Fisher, and Majaz Moonis
Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure, Todd M. Savarese, Taichang Jang, Hoi Pang Low, Rebecca Salmonsen, N. Scott Litofsky, Zdenka Matijasevic, Alonzo H. Ross, and Lawrence D. Recht
Functional, perfusion and diffusion MRI of acute focal ischemic brain injury, Qiang Shen, Hongxia Ren, Haiying Cheng, Marc Fisher, and Timothy Q. Duong
Statistical prediction of tissue fate in acute ischemic brain injury, Qiang Shen, Hongxia Ren, Marc Fisher, and Timothy Q. Duong
Effect of the Glycine Antagonist Gavestinel on cerebral infarcts in acute stroke patients, a randomized placebo-controlled trial: The GAIN MRI Substudy, Steven Warach, David Kaufman, David Chiu, Thomas Devlin, Marie Luby, Ajaz Rashid, Linda Clayton, Markku Kaste, Kennedy R. Lees, Ralph L. Sacco, and Marc Fisher
Submissions from 2004
The aging factor in health and disease: the promise of basic research on aging, Robert N. Butler, Huber R. Warner, T. Franklin Williams, Steven N. Austad, Jacob A. Brody, Judith Campisi, Anthony Cerami, Gene D. Cohen, Vincent J. Cristofalo, David A. Drachman, Caleb E. Finch, Irwin Fridovich, Calvin B. Harley, Richard J. Havlik, George M. Martin, Richard A. Miller, S. Jay Olshansky, Olivia M. Pereira-Smith, James R. Smith, Richard L. Sprott, Michael D. West, John R. Wilmoth, and Woodring E. Wright
Emerging therapies for cerebrovascular disorders, Antonio Davalos and Marc Fisher
Fading Minds and Hanging Chads: Alzheimer’s Disease and the Right to Vote, David A. Drachman
Statins in the Prevention and Treatment of Alzheimer’s Disease, David A. Drachman
Applications of diffusion/perfusion magnetic resonance imaging in experimental and clinical aspects of stroke, Timothy Q. Duong and Marc Fisher
Emerging therapies for cerebrovascular disorders, Marc Fisher and Antonio Davalos
Noninvasive quantification of brain edema and the space-occupying effect in rat stroke models using magnetic resonance imaging, Tibo Gerriets, Erwin Stolz, Maureen Walberer, Clemens Muller, Alexander Kluge, A. Bachmann, Marc Fisher, Manfred Kaps, and Georg Bachmann
Middle cerebral artery occlusion during MR-imaging: investigation of the hyperacute phase of stroke using a new in-bore occlusion model in rats, Tibo Gerriets, Erwin Stolz, Maureen Walberer, Clemens Muller, Alexander Kluge, Manfred Kaps, Marc Fisher, and Georg Bachmann
Complications and pitfalls in rat stroke models for middle cerebral artery occlusion: a comparison between the suture and the macrosphere model using magnetic resonance angiography, Tibo Gerriets, Erwin Stolz, Maureen Walberer, Clemens Muller, Carina Rottger, Alexander Kluge, Manfred Kaps, Marc Fisher, and Georg Bachmann
Investigation of techniques to quantify in vivo lesion volume based on comparison of water apparent diffusion coefficient (ADC) maps with histology in focal cerebral ischemia of rats, Mark Kazemi, Matthew D. Silva, Fuhai Li, Marc Fisher, and Christopher H. Sotak
Microsphere-induced embolic stroke: an MRI study, Orna Mayzel-Oreg, Tsuyoshi Omae, Mark Kazemi, Fuhai Li, Marc Fisher, Yoram Cohen, and Christopher H. Sotak
Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia, Xiangjun Meng, Marc Fisher, Qiang Shen, Christopher H. Sotak, and Timothy Q. Duong
Antiplatelet treatment for secondary prevention of acute ischemic stroke and transient ischemic attacks: mechanisms, choices and possible emerging patterns of use, Majaz Moonis and Marc Fisher
Antihypertensive medications for risk reduction of first and recurrent ischemic stroke, Vasantha Padma, Marc Fisher, and Majaz Moonis
Partial-volume effect on ischemic tissue-fate delineation using quantitative perfusion and diffusion imaging on a rat stroke model, Hongxia Ren, Qiang Shen, Juergen F. Bardutzky, Marc Fisher, and Timothy Q. Duong
Effects of reperfusion on ADC and CBF pixel-by-pixel dynamics in stroke: characterizing tissue fates using quantitative diffusion and perfusion imaging, Qiang Shen, Marc Fisher, Christopher H. Sotak, and Timothy Q. Duong
Dynamic tracking of acute ischemic tissue fates using improved unsupervised ISODATA analysis of high-resolution quantitative perfusion and diffusion data, Qiang Shen, Hongxia Ren, Marc Fisher, James P. Bouley, and Timothy Q. Duong
Submissions from 2003
Preventing and treating Alzheimer’s disease: strategies and prospects, David A. Drachman
Imaging as a Surrogate Marker in Clinical Trials, Marc Fisher
Ongoing trials and future directions for acute ischemic stroke treatment, Marc Fisher
Ongoing Trials and Future Directions for Acute Ischemic Stroke Treatment, Marc Fisher
Recommendations for advancing development of acute stroke therapies: Stroke Therapy Academic Industry Roundtable 3, Marc Fisher
The ischemic penumbra: identification, evolution and treatment concepts, Marc Fisher
Using Diffusion-Perfusion MRI in Animal Models for Drug Development, Marc Fisher
Emerging therapies for acute ischemic stroke: new therapies on trial, Marc Fisher and Thomas G. Brott
Magnetic Resonance Imaging in Stroke, Marc Fisher, Stephen Davis, and Steven Warach
Combination Therapies, Restorative Therapies and Future Directions, Marc Fisher and Majaz Moonis
Neurovascular Disorders, Marc Fisher, E. Orberk, and M. Ramzan
New perspectives on developing acute stroke therapy, Marc Fisher and Rajiv Ratan
The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats, Tibo Gerriets, Fuhai Li, Matthew D. Silva, Xiangjun Meng, Mathew E. Brevard, Christopher H. Sotak, and Marc Fisher
Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: adverse effects of hypothalamic damage and strategies for its avoidance, Tibo Gerriets, Erwin Stolz, Maureen Walberer, Manfred Kaps, Georg Bachmann, and Marc Fisher
Neuroprotective effects of a new synthetic peptide, CMX-9236, in in vitro and in vivo models of cerebral ischemia, Victor E. Shashoua, David S. Adams, Anne Boyer-Boiteau, Ann Cornell-Bell, Fuhai Li, and Marc Fisher
Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging, Qiang Shen, Xiangjun Meng, Marc Fisher, Christopher H. Sotak, and Timothy Q. Duong
Submissions from 2002
Hat size, brain size, intelligence, and dementia: what morphometry can tell us about brain function and disease, David A. Drachman
The treatment of Alzheimer's disease: where have we been, and where are we going, David A. Drachman
Dementia, butterfly ballots, and voter competence, Victor W. Henderson and David A. Drachman
Considering the role of heparin and low-molecular-weight heparins in acute ischemic stroke, Majaz Moonis and Marc Fisher
Aging and Dementia: principles, evaluation and diagnosis, Sudha Seshadri and David A. Drachman
Separating changes in the intra- and extracellular water apparent diffusion coefficient following focal cerebral ischemia in the rat brain, Matthew D. Silva, Tsuyoshi Omae, Karl G. Helmer, Fuhai Li, Marc Fisher, and Christopher H. Sotak
Screening for dementia in "real world" settings: the cognitive assessment screening test: CAST, Joan M. Swearer, David A. Drachman, Lynn Li, Kevin J. Kane, Brian Dessureau, and Patricia Tabloski
Submissions from 2001
Practice Parameters: Diagnosis, Treatment, and Early Detection of Dementia, David A. Drachman
Stroke Therapy (2nd ed.), Marc Fisher