Midlife physical activity preserves lower extremity function in older adults: age gene/environment susceptibility-Reykjavik study
Department of Medicine, Division of Geriatric Medicine; Meyers Primary Care Institute
Medical Subject Headings
Aged; Aging; Cognition Disorders; Environmental Exposure; Female; Forecasting; *Genetic Predisposition to Disease; *Geriatric Assessment; Humans; Iceland; Lower Extremity; Male; Morbidity; Motor Activity
Geriatrics | Health Services Research | Primary Care
OBJECTIVES: To examine the long-term association between midlife physical activity (PA) and lower extremity function (LEF) in late life.
DESIGN: Longitudinal study with an average of 25 years of follow-up. SETTING: Community-dwelling old population in Reykjavik, Iceland.
PARTICIPANTS: Four thousand seven hundred fifty-three community-dwelling men and women (mean age 76 +/- 6) in Reykjavik, Iceland.
MEASUREMENTS: On the basis of weekly hours of regular PA reported at the midlife examination, participants were classified as active or inactive. Measures of LEF in late life were gait speed on a 6-m walk, Timed Up and Go (TUG), and knee extension (KE) strength tests. Linear regression analysis was used to examine the association.
RESULTS: Participants who were active in midlife had significantly better LEF (faster gait speed, beta = 0.50, P
CONCLUSION: Regular PA in midlife is associated with better performance of LEF in later life, even after controlling for late-life cognitive function. Geriatrics Society.
Chang, Milan; Saczynski, Jane S.; Snaedal, Jon; Bjornsson, Sigurbjorn; Einarsson, Bjorn; Garcia, Melissa E.; Aspelund, Thor; Siggeirsdottir, Kristine; Gudnason, Vilmundur; Launer, Lenore J.; Harris, Tamara B.; and Jonsson, Palmi V., "Midlife physical activity preserves lower extremity function in older adults: age gene/environment susceptibility-Reykjavik study" (2013). Meyers Primary Care Institute Publications and Presentations. 643.