UMass Chan Affiliations
Department of Medicine, Division of Geriatric MedicineMeyers Primary Care Institute
Document Type
Journal ArticlePublication Date
2008-04-08Keywords
AgedBreast Neoplasms
Chemoprevention
Comorbidity
Cross-Sectional Studies
Female
*Health Knowledge, Attitudes, Practice
Humans
Middle Aged
Questionnaires
Raloxifene
Risk Factors
Selective Estrogen Receptor Modulators
Tamoxifen
Community Health and Preventive Medicine
Health Services Research
Primary Care
Metadata
Show full item recordAbstract
OBJECTIVES: The study aim is to describe interest in breast cancer chemoprevention among older women without a history of breast cancer and to determine whether aging-related factors such as diminished life expectancy, increasing comorbidity and medication burden attenuate chemoprevention interest. DESIGN: Cross-sectional survey. SETTING: University of Pennsylvania Health System. PARTICIPANTS: Four-hundred fifty-seven community-dwelling women aged 60-65 years old who were potentially eligible for breast cancer chemoprevention according to guidelines linking risk and eligibility to age. MEASUREMENTS: Interest in breast cancer chemopre vention, Gail model breast cancer risk, perceived breast cancer risk, breast cancer worry, self-reported health status and comorbidities, and self-reported perceived life expectancy. RESULTS: Of 457 participants, 11.2% reported being interested in taking chemoprevention, 40.9% reported no interest, and 47.9% reported being unsure about their interest in chemoprevention. Overall, interest in chemoprevention was not associated with individual Gail model breast cancer risk. In adjusted analysis, lack of interest among high-risk women was associated with low breast cancer worry and low perceived risk. Conversely, interest in chemoprevention among low risk women was associated with greater breast cancer worry. Age-related factors hypothesized to affect chemoprevention interest, including subjective life expectancy, increased comorbidity, and number of daily medications did not attenuate chemoprevention interest. CONCLUSION: Breast cancer worry and perceived breast cancer risk contribute to the lack of correlation between interest in breast cancer chemoprevention and objective breast cancer risk. Perceived life expectancy, increased comorbidity, and medication burden do not attenuate chemoprevention interest among older women.Source
Breast Cancer Res Treat. 2008 Apr;108(3):435-53. Epub 2007 Jun 7. Link to article on publisher's siteDOI
10.1007/s10549-007-9614-8Permanent Link to this Item
http://hdl.handle.net/20.500.14038/37049PubMed ID
17554628Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1007/s10549-007-9614-8