Polyarteritis nodosa presenting as pancytopenia: case report and review of the literature
Meyers Primary Care Institute; Department of Medicine, Division of Rheumatology
Medical Subject Headings
Adult; Humans; Male; Pancytopenia; Polyarteritis Nodosa
Health Services Research | Medicine and Health Sciences
Polyarteritis nodosa (PAN) is not commonly associated with hematologic abnormalities. We report the first case of pancytopenia as the presenting symptom of PAN. There was no associated malignancy or reactive hemophagocytic syndrome (RHS) to explain the findings. The patient, after successful treatment of PAN, subsequently developed RHS a few years later. He is the fourth reported case of RHS in a patient with PAN. In addition to describing the patient's presentation and clinical course, a systematic review of the literature was performed examining the association between hematologic conditions, including RHS, and PAN.
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Citation: Rheumatol Int. 2008 Aug;28(10):1049-51. Epub 2008 Mar 27. Link to article on publisher's site