Title

An autophagy-independent function for Beclin 1 in cancer

UMMS Affiliation

Department of Molecular, Cell and Cancer Biology; UMass Metabolic Network

Date

1-2-2016

Document Type

Article

Disciplines

Biochemistry | Cancer Biology | Cell Biology | Cellular and Molecular Physiology | Molecular Biology

Abstract

The involvement of Beclin 1 in cancer has been attributed primarily to its role in autophagy initiation. Our recent findings identify a novel, alternative mechanism by which Beclin 1 can impact tumor progression, through the regulation of growth factor receptor signaling.

Rights and Permissions

Citation: Mol Cell Oncol. 2016 Jan 2;3(1). pii: e1030539. Epub 2015 Apr 14. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Keywords

autophagy, beclin 1, cancer, endocytosis, growth factor receptor, signaling

PubMed ID

26998512