University of Massachusetts Medical School - Department of Microbiology and Physiological Systems - Publications and Presentations | Microbiology and Physiological Systems | University of Massachusetts Medical School

Skip to main content

Microbiology and Physiological Systems Publications and Presentations

The Department of Microbiology and Physiological Systems (MaPS) was founded in 2010, and is the product of a merger between two departments, one focused on microbiology, genetics, and immunology, and the other focused on physiology. Capitalizing on the strength of the respective scientific research programs, the resulting department has strong and synergistic expertise in bacterial and viral pathogenesis, immunology, signal transduction, and fundamental cellular physiology. Current departmental research targets include viral and bacterial pathogens affecting the nervous, respiratory, and digestive systems. The mission of the new department is to address important biological questions broadly relevant to infectious disease and encompassing multiple levels of biological organization, including an understanding of pathogen effects on their target organ systems. This collection showcases the journal articles and other publications and presentations written by faculty and researchers of the Department of Microbiology and Physiological Systems. See earlier collections for selected Physiology and Molecular Genetics and Microbiology publications published before the departmental merger.

Publications from 2013 2013

Serial Transplantation of Bone Marrow to Test Self-renewal Capacity of Hematopoietic Stem Cells In Vivo, Charusheila Ramkumar, Rachel M. Gerstein, and Hong Zhang

Publications from 2012 2012

The Acid-Sensitive, Anesthetic-Activated Potassium Leak Channel, KCNK3, Is Regulated By 14-3-3beta-Dependent, PKC-Mediated Endocytic Trafficking, Luke Gabriel, Anatoli Lvov, Demetra Orthodoxou, Ann R. Rittenhouse, William R. Kobertz, and Haley E. Melikian

Gene transfer in the lung using recombinant adeno-associated virus, Alisha Gruntman, Christian Mueller, Terence R. Flotte, and Guangping Gao

Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase, Muneer G. Hasham, Kathy J. Snow, Nina M. Donghia, Jane A. Branca, Mark D. Lessard, Janet Stavnezer, Lindsay S. Shopland, and Kevin D. Mills

Disruption of IFT Complex A Causes Cystic Kidneys without Mitotic Spindle Misorientation, Julie A. Jonassen, Jovenal T. San Agustin, Stephen P. Baker, and Gregory J. Pazour

Allele- and tir-independent functions of intimin in diverse animal infection models, Emily M. Mallick, Michael J. Brady, Steven A. Luperchio, Vijay K. Vanguri, Loranne Magoun, Hui Liu, Barbara J. Sheppard, Jean Mukherjee, Arthur Donohue-Rolfe, Saul Tzipori, John M. Leong, and David B. Schauer

Production and discovery of novel recombinant adeno-associated viral vectors, Christian Mueller, Li Zhong, Dmitry Ratner, Miguel Sena-Esteves, and Guangping Gao

Rabenosyn-5 Defines the Fate of the Transferrin Receptor Following Clathrin-mediated Endocytosis, Deanna M. Navaroli, Karl D. Bellve, Clive Standley, Lawrence M. Lifshitz, James Cardia, David Lambright, Deborah Leonard, Kevin E. Fogarty, and Silvia Corvera

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice, Charusheila Ramkumar, Yahui Kong, Hang Cui, Suyang Hao, Stephen N. Jones, Rachel M. Gerstein, and Hong Zhang

The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells, Anna J. Ucher, Erin K. Linehan, George W. Teebor, Carol E. Schrader, and Janet Stavnezer

Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility, Margaretha Van der Deen, Jacqueline Akech, David S. Lapointe, Sneha Gupta, Daniel W. Young, Martin A. Montecino, Mario Galindo, Jane B. Lian, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors, Jun Xie, Stefan L. Ameres, Randall H. Friedline, Jui-Hung Hung, Yu Zhang, Qing Xie, Li Zhong, Qin Su, Ran He, Mengxin Li, Huapeng Li, Xin Mu, Hongwei Zhang, Jennifer A. Broderick, Jason K. Kim, Zhiping Weng, Terence R. Flotte, Phillip D. Zamore, and Guangping Gao

Publications from 2011 2011

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism, Jennifer E. Griffin, Jeffrey D. Gawronski, Michael A. Dejesus, Thomas R. Ioerger, Brian J. Akerley, and Christopher M. Sassetti

Editorial overview, Frances Lund and Janet Stavnezer

AID binds cooperatively with UNG and Msh2-Msh6 to Ig switch regions dependent upon the AID C terminus, Sanjay Ranjit, Lyne Khair, Erin K. Linehan, Anna J. Ucher, Mrinmay Chakrabarti, Carol E. Schrader, and Janet Stavnezer

Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants, Nicholas Renzette, Bornali Bhattacharjee, Jeffrey D. Jensen, Laura L. Gibson, and Timothy F. Kowalik

A novel zinc binding system, ZevAB, is critical for survival of nontypeable Haemophilus influenzae in a murine lung infection model, Charles V. Rosadini, Jeffrey D. Gawronski, Daniel Raimunda, José M Argüello, and Brian J. Akerley

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells, Ori Staszewski, Richard E. Baker, Anna J. Ucher, Raygene Martier, Janet Stavnezer, and Jeroen E. J. Guikema

Complex regulation and function of activation-induced cytidine deaminase, Janet Stavnezer

ArcA-regulated glycosyltransferase lic2B promotes complement evasion and pathogenesis of nontypeable Haemophilus influenzae, Sandy M. S. Wong, Frank St. Michael, Andrew Cox, Sanjay Ram, and Brian J. Akerley

Publications from 2010 2010

p53 represses class switch recombination to IgG2a through its antioxidant function, Jeroen E. J. Guikema, Carol E. Schrader, Michael H. Brodsky, Erin K. Linehan, Adam Richards, Nahla El Falaky, Daniel H. LI, Hayla Karen Sluss, Eva Szomolanyi-Tsuda, and Janet Stavnezer

The role of Apex2 in class-switch recombination of immunoglobulin genes, Jeroen E. J. Guikema, Janet Stavnezer, and Carol E. Schrader

Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching, Janet Stavnezer, Andrea Bjorkman, Likun Du, Alberto Cagigi, and Qiang Pan-Hammarstrom