Luna Lab Publications

Title

Multiple phase equilibria in binary mixtures of phospholipids

UMMS Affiliation

Department of Cell and Developmental Biology

Date

6-2-1978

Document Type

Article

Medical Subject Headings

Freeze Fracturing; *Liposomes; Microscopy, Electron; Myristates; Palmitates; *Phosphatidylcholines; *Phosphatidylethanolamines; *Pulmonary Surfactants; Stearates; Thermodynamics

Disciplines

Biochemistry, Biophysics, and Structural Biology | Cell and Developmental Biology

Abstract

Approximate phse diagrams describing lateral phase separations are given for binary mixtures of dimyristoyl phosphatidylcholine with dipalmitoyl phosphatidylcholine, distearoyl phosphatidycholine, and dipalmitoyl phosphatidylethanolamine. These diagrams are based in part on freeze-fracture electron microscopic data. These phase diagrams represent an improvement over previous studies in that both solid phses (Pbeta' and Lbeta') of the phosphatidylcholines are included. Further consideration is given to the problem of binary mixtures in which there are two Pbeta' phases that do not form a continuous range of solid solutions.

Comments

Citation: Biochim Biophys Acta. 1978 Jun 2;509(3):462-73. DOI 10.1016/0005-2736(78)90240-7

At the time of publication, Elizabeth Luna was not yet affiliated with the University of Massachusetts Medical School.

Related Resources

Link to Article in PubMed

PubMed ID

580767