Sonographic appearance of the endometrium and ovaries during cycles stimulated with human menopausal gonadotropin
Department of Cell Biology; Information Services, Academic Computing Services; Department of Radiology
Adult; Endometrium; Estradiol; Female; Humans; Infertility, Female; Menotropins; Menstrual Cycle; Middle Aged; Ovarian Follicle; Ovary; Ovulation; Pregnancy; Pregnancy Rate
Cell and Developmental Biology | Cell Biology | Obstetrics and Gynecology
OBJECTIVE: To determine the measurable factors that correlated with a higher conception ratio in one of our subpopulations of infertility patients.
STUDY DESIGN: We analyzed 58 menstrual cycles in 24 consecutive infertility patients treated only with human menopausal gonadotropin (hMG) and intrauterine insemination between January 1992 and February 1993 to compare those cycles leading to conception with those that did not with regard to certain factors: endometrial thickness, endometrial layering, number of follicles > or = 15 mm in diameter, peak estradiol level and number of cycles prior to conception.
RESULTS: All conceptions occurred in cycles that showed endometrial layering. No patient conceived if the endometrial thickness was < 8 mm. The incidence of conception increased with the number of follicles (one to three) measuring > 15 mm in average diameter. No patient conceived if the serum estradiol was < 192 pg/mL. No conceptions occurred after three successive cycles of treatment.
CONCLUSION: Endometrial layering, endometrial thickness of at least 8 mm, a higher number of follicles (up to three) with an average of 15 mm and a serum estradiol level of at least 192 pg/mL correlated with a higher rate of conception.
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Citation: J Reprod Med. 1996 Jul;41(7):509-14.