Title

Frequency of painless myocardial ischemia during exercise tolerance testing in patients with and without diabetes mellitus

UMMS Affiliation

Information Services, Academic Computing Services; Department of Cell Biology; Department of Medicine, Division of Endocrinology and Metabolism

Date

1-1-1987

Document Type

Article

Subjects

Coronary Disease; Diabetic Angiopathies; *Exercise Test; Female; Heart Catheterization; Humans; Male; Middle Aged; *Pain

Disciplines

Cardiology | Endocrinology, Diabetes, and Metabolism

Abstract

To evaluate the frequency of painless myocardial ischemia, all patients with positive exercise tolerance test responses (at least 2 mm of ST depression) from 1983 to 1985 were examined. Of the 211 patients with exercise-induced ischemia, 101 (48%) did not have pain during the ischemic period; 26 (12%) had diabetes mellitus, 24 of whom (92%) had type II diabetes mellitus. Lack of pain was not correlated with age, gender, history of cigarette smoking, systemic hypertension, past acute myocardial infarction, coronary artery bypass grafting, use of beta-blocking or calcium-channel blocking drugs, number of narrowed coronary arteries or average calculated ejection fraction at cardiac catheterization. Patients with painless myocardial ischemia were less often taking nitrates (39% vs 55%, p less than 0.05) and reported prior episodes of chest pain less often (50% vs 82%, p less than 0.01) than control subjects. There was no difference in the frequency of painless myocardial ischemia between patients with and without diabetes mellitus (54% vs 47%). Duration of exercise was shorter in patients with diabetes mellitus and in patients who had pain with myocardial ischemia. No significant difference in age, gender, use of nitrates, beta-blocking or calcium-channel blocking drugs, history of myocardial infarction, angina pectoris or cigarette smoking was found between diabetic and nondiabetic patients. Systemic hypertension was more common in diabetic patients. Thus, painless myocardial ischemia is common in our patients with positive exercise tolerance test responses, but its frequency is similar in diabetic and nondiabetic patients.

Rights and Permissions

Citation: Am J Cardiol. 1987 Jan 1;59(1):61-5.

Related Resources

Link to article in PubMed

PubMed ID

3812254