This collection showcases the books, journal articles, book reviews, and other publications and presentations written by faculty and researchers of the Department of Medicine's Division of Infectious Diseases and Immunology.

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Publications from 2009

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Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K, Yu Sun, Minako Ishibashi, Tracie Seimon, Mingsum Lee, Sudarshana M. Sharma, Katherine A. Fitzgerald, Andriy O. Samokhin, Yibin Wang, Scott Sayers, Masanori Aikawa, W. Gray Jerome, Michael C. Ostrowski, Dieter Bromme, Peter Libby, Ira A. Tabas, Carrie L. Welch, and Alan R. Tall

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Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis, Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paul Paquette, Neal S. Silverman, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai

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Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling, Connie W. Woo, Dongying Cui, Jerry Arellano, Bernhard Dorweiler, Heather Harding, Katherine A. Fitzgerald, David Ron, and Ira Tabas

Publications from 2008

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Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway, Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, Nicholas Paquette, and Neal S. Silverman

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Positive and negative regulation of the Drosophila immune response, Kamna Aggarwal and Neal S. Silverman

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Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination, Mumtaz Yaseen Balkhi, Katherine A. Fitzgerald, and Paula M. Pitha

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Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi, Daniella C. Bartholomeu, Catherine Ropert, Mariane B. Melo, Peggy Parroche, Caroline F. Junqueira, Santuza M. R. Teixeira, Cherilyn M. Sirois, Pia Kasperkovitz, Cathrine F. Knetter, Egil Lien, Eicke Latz, Douglas T. Golenbock, and Ricardo T. Gazzinelli

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TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA, Marie Charrel-Dennis, Eicke Latz, Kristen A. Halmen, Patrick Trieu-Cuot, Katherine A. Fitzgerald, Dennis L. Kasper, and Douglas T. Golenbock

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A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts, Anne-Danielle C. Chessler, Ludmila R. Ferreira P., Tun-Han Chang, Katherine A. Fitzgerald, and Barbara A. Burleigh

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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens, Karim C. El Kasmi, Joseph E. Qualls, John T. Pesce, Amber M. Smith, Robert W. Thompson, Marcela Henao-Tamayo, Randall J. Basaraba, Till Konig, Ulrike Schleicher, Mi-Sun Koo, Gilla Kaplan, Katherine A. Fitzgerald, Elaine I. Tuomanen, Ian M. Orme, Thirumala-Devi Kanneganti, Christian Bogdan, Thomas A. Wynn, and Peter J. Murray

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Hormonal regulation of the humoral innate immune response in Drosophila melanogaster, Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, Marc Tatar, and Neal S. Silverman

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Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling, Felix Geeraedts, Nadege Goutagny, Veit Hornung, Martina Severa, Aalzen de Haan, Judity Pool, Jan Wilschut, Katherine A. Fitzgerald, and Anke Huckriede

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta, Annett Halle, Veit Hornung, Gabor C. Petzold, Cameron R. Stewart, Brian G. Monks, Thomas Reinheckel, Katherine A. Fitzgerald, Eicke Latz, Kathryn J. Moore, and Douglas T. Golenbock

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The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3, Rowan Higgs, Joan Ni Gabhann, Nadia Ben Larbi, Eamon P. Breen, Katherine A. Fitzgerald, and Caroline A. Jefferies

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization, Veit Hornung, Franz G. Bauernfeind, Annett Halle, Eivind O. Samstad, Hajime Kono, Kenneth L. Rock, Katherine A. Fitzgerald, and Eicke Latz

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Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein, Xueqiao Liu, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, Robert W. Finberg, and David M. Knipe

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Engineered intermonomeric disulfide bonds in the globular domain of Newcastle disease virus hemagglutinin-neuraminidase protein: implications for the mechanism of fusion promotion, Paul J. Mahon, Anne M. Mirza, Thomas A. Musich, and Ronald M. Iorio

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Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virus, Anuja Mathew, Joel M. O'Bryan, William L. Marshall, Girish J. Kotwal, Masanori Terajima, Sharone Green, Alan L. Rothman, and Francis A. Ennis

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Role of innate immunity in transplantation tolerance., David M. Miller, Aldo A. Rossini, and Dale L. Greiner

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Viral infection: a potent barrier to transplantation tolerance, David M. Miller, Thomas B. Thornley, Dale L. Greiner, and Aldo A. Rossini

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TLR agonists abrogate co-stimulation blockade-induced mixed chimerism and transplantation tolerance., David M. Miller, Thomas B. Thornley, Todd Pearson, Masahiro Yamazaki, Michael A. Brehm, Aldo A. Rossini, and Dale L. Greiner

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Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response, Andrea Paun, Jorgen T. Reinert, Zhaozhao Jiang, Carey L. Medin, Mumtaz Yaseen Balkhi, Katherine A. Fitzgerald, and Paula M. Pitha

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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment, Todd Pearson, Leonard D. Shultz, David M. Miller, Marie A. King, Joseph Laning, William Fodor, Amy Cuthbert, Lisa M. Burzenski, Bruce Gott, Bonnie L. Lyons, Oded Foreman, Aldo A. Rossini, and Dale L. Greiner

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Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance, Wenji Piao, Chang Song, Haiyan Chen, Larry M. Wahl, Katherine A. Fitzgerald, Luke A. J. O'Neill, and Andrei E. Medvedev

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Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA, Zaida G. Ramirez-Ortiz, Charles A. Specht, Jennifer P. Wang, Chrono K. Lee, Daniella C. Bartholomeu, Ricardo T. Gazzinelli, and Stuart M. Levitz

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Immunogenicity and protection efficacy of subunit-based smallpox vaccines using variola major antigens, Pavlo V. Sakhatskyy, Shixia Wang, Chuanyou Zhang, Te-Hui Chou, Michael G. Kishko, and Shan Lu

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Immunology. The right resident bugs, Neal S. Silverman and Nicholas Paul Paquette

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Hepatitis C and innate immunity: recent advances, Gyongyi Szabo and Angela Dolganiuc

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Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A, Claribel P. Taylor, Hemachand Tummala, Deborah Molrine, Lisa Davidson, Richard J. Farrell, Anthony J. Lembo, Patricia L. Hibberd, Israel Lowy, and Ciaran P. Kelly

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Improved induction of antibodies against key neutralizing epitopes by HIV-1 gp120 DNA prime-protein boost vaccination compared to gp120 protein only vaccination, Michael Vaine, Shixia Wang, Emma T. Crooks, Pengfei Jiang, David C. Montefiori, James Binley, and Shan Lu

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Class II major histocompatibility complex tetramer staining: progress, problems, and prospects, Sabrina S. Vollers and Lawrence J. Stern

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Cryptococcus neoformans enters the endolysosomal pathway of dendritic cells and is killed by lysosomal components, Karen L. Wozniak and Stuart M. Levitz

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Autophagic control of listeria through intracellular innate immune recognition in drosophila, Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Neal S. Silverman, Tamotsu Yoshimori, and Shoichiro Kurata

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Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses, Shenghua Zhou, Annett Halle, Evelyn A. Kurt-Jones, Anna M. Cerny, Ermelinda Porpiglia, Michael Rogers, Douglas Golenbock, and Robert W. Finberg

Publications from 2007

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Peptidoglycan recognition in Drosophila, Kamna Aggarwal and Neal S. Silverman

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RIG-I: tri-ing to discriminate between self and non-self RNA, Andrew G. Bowie and Katherine A. Fitzgerald

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Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif, Pamela Cook, Sabine Totemeyer, Catherine Stevenson, Katherine A. Fitzgerald, Masahiro Yamamoto, Shizuo Akira, Duncan J. Maskell, and Clare E. Bryant

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Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster, Deniz Erturk Hasdemir, Nicholas Paul Paquette, Kamna Aggarwal, and Neal S. Silverman

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Immunology. The shape of things to come, Katherine A. Fitzgerald and Douglas T. Golenbock

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CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help, Maria Genevieve H. Hernandez, Lianjun Shen, and Kenneth L. Rock

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Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM, Amy G. Hise, Katrin Daehnel, Illona Gillette-Ferguson, Eun Cho, Helen F. McGarry, Mark J. Taylor, Douglas T. Golenbock, Katherine A. Fitzgerald, James W. Kazura, and Eric Pearlman

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Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity, Marie A. King, Todd Pearson, Leonard D. Shultz, Jean H. Leif, Rita Bottino, Massimo Trucco, Mark A. Atkinson, Clive Wasserfall, Kevan C. Herold, John P. Mordes, Aldo A. Rossini, and Dale L. Greiner

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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene, Marie A. King, Todd Pearson, Leonard D. Shultz, Jean H. Leif, Rita Bottino, Massimo Trucco, Mark A. Atkinson, Clive Wasserfall, Kevan C. Herold, Robert T. Woodland, Madelyn R. Schmidt, Bruce A. Woda, Michael J. Thompson, Aldo A. Rossini, and Dale L. Greiner

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Ligand-induced conformational changes allosterically activate Toll-like receptor 9, Eicke Latz, Anjali Verma, Alberto Visintin, Mei Gong, Cherilyn M. Sirois, Dionne C. G. Klein, Brian G. Monks, C. James McKnight, Marc S. Lamphier, W. Paul Duprex, Terje Espevik, and Douglas T. Golenbock

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NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1, Sinead M. Miggin, Eva M. Palsson-McDermott, Aisling Dunne, Caroline A. Jefferies, Emmanuel Pinteaux, Kathy Banahan, Caroline Murphy, Paul Moynagh, Masahiro Yamamoto, Shizuo Akira, Nancy Rothwell, Douglas T. Golenbock, Katherine A. Fitzgerald, and Luke A. J. O'Neill

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Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA, Marie-Louise Newell, Sharon Huang, Simona Fiore, Claire Thorne, Laurent Mandelbrot, John L. Sullivan, Robert Maupin, Isaac Delke, D. Heather Watts, Richard D. Gelber, and Colleen K. Cunningham

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The role of type I interferons in TLR responses, Susie J. Noppert, Katherine A. Fitzgerald, and Paul J. Hertzog

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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis, Zachary J. Roberts, Nadege Goutagny, Pin-Yu Perera, Hiroki Kato, Himanshu Kumar, Taro Kawai, Shizuo Akira, Ram Savan, David van Echo, Katherine A. Fitzgerald, Howard A. Young, Lai-Ming Ching, and Stefanie N. Vogel

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TLR-mediated activation of type I IFN during antiviral immune responses: fighting the battle to win the war, Martina Severa and Katherine A. Fitzgerald

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YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction, Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, Jon D. Goguen, and Neal S. Silverman

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE, Jane Tian, Ana Maria Avalos, Su-Yau Mao, Bo Chen, Kannaki Senthil, Herren Wu, Peggy Parroche, Stacey Drabic, Douglas T. Golenbock, Cherilyn M. Sirois, Jing Hua, Ling Ling An, Laurent Audoly, Greg La Rosa, Angelika Bierhaus, Peter Naworth, Ann Marshak-Rothstein, Mary K. Crow, Katherine A. Fitzgerald, Eicke Latz, Peter A. Kiener, and Anthony J. Coyle

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Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses, Charles Fenton Towne, Ian A. York, Levi B. Watkin, John S. Lazo, and Kenneth L. Rock

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Fighting infection fly-style, Louisa Wu and Neal S. Silverman

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Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice, Masahiro Yamazaki, Todd Pearson, Michael A. Brehm, David M. Miller, Julie A. Mangada, Thomas G. Markees, Leonard D. Shultz, John P. Mordes, Aldo A. Rossini, and Dale L. Greiner

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Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection, Shenghua Zhou, Evelyn A. Kurt-Jones, Katherine A. Fitzgerald, Jennifer P. Wang, Anna M. Cerny, Melvin Chan, and Robert W. Finberg

Publications from 2006

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MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals, Chun-Jen Chen, Yan Shi, Arron Hearn, Katherine A. Fitzgerald, Douglas T. Golenbock, George W. Reed, Shizuo Akira, and Kenneth L. Rock

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Host-pathogen interactions in drosophila: new tricks from an old friend, Sara Cherry and Neal S. Silverman

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Sorting out Toll signals, Katherine A. Fitzgerald and Zhijian J. Chen

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Pattern recognition receptors: an update, Nadege Goutagny and Katherine A. Fitzgerald

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Pin-ning down immune responses to RNA viruses, Nadege Goutagny, Martina Severa, and Katherine A. Fitzgerald

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PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan, Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, Shoichiro Kurata, and Neal S. Silverman

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Integrity of membrane lipid rafts is necessary for the ordered assembly and release of infectious Newcastle disease virus particles, Jason P. Laliberte, Lori McGinnes, Mark E. Peeples, and Trudy G. Morrison

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TLR9 and the recognition of self and non-self nucleic acids, Marc S. Lamphier, Cherilyn M. Sirois, Anjali Verma, Douglas T. Golenbock, and Eicke Latz

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Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins, Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Neal S. Silverman, Shoichiro Kurata, and Byung-Ha Oh

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Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling, Anne F. McGettrick, Elizabeth K. Brint, Eva M. Palsson-McDermott, Daniel C. Rowe, Douglas T. Golenbock, Nicholas J. Gay, Katherine A. Fitzgerald, and Luke A. J. O'Neill

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TOLLing away in Brazil, Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, Neal S. Silverman, and Neil Cartwright

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Complex T cell memory repertoires participate in recall responses at extremes of antigenic load, Yuri N. Naumov, Elena N. Naumova, Shalyn Catherine Clute, Levi B. Watkin, Kalyani Kota, Jeffrey P. Gorski, and Liisa K. Selin

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The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction, Daniel C. Rowe, Anne F. McGettrick, Eicke Latz, Brian G. Monks, Nicholas J. Gay, Masahiro Yamamoto, Shizuo Akira, Luke A. J. O'Neill, Katherine A. Fitzgerald, and Douglas T. Golenbock

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S-nitrosothiol depletion in amyotrophic lateral sclerosis, Christopher M. Schonhoff, Masaaki Matsuoka, Hemachand Tummala, Michael A. Johnson, Alvaro G. Estevez, Rui Wu, Andres Kamaid, Karina C. Ricart, Yuichi Hashimoto, Benjamin M. Gaston, Timothy L. Macdonald, Zuoshang Xu, and Joan B. Mannick

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Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1, Martina Severa, Eliana M. Coccia, and Katherine A. Fitzgerald

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Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs), Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, Neal S. Silverman, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza

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Toll-like receptor 3 signaling evokes a proinflammatory and proliferative phenotype in human vascular smooth muscle cells, Xin Yang, Vanishree Murthy, Kelly Schultz, Jeffrey B. Tatro, Katherine A. Fitzgerald, and Debbie Beasley

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Modest but reproducible inhibition of human immunodeficiency virus type 1 infection in macrophages following LEDGFp75 silencing, Steven P. Zielske and Mario Stevenson

Publications from 2005

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Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4, Ezra Aksoy, Wim Vanden Berghe, Sophie Detienne, Zoulikha Amraoui, Katherine A. Fitzgerald, Guy Haegeman, Michel Goldman, and Fabienne Willems

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Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis, Shalyn Catherine Clute, Levi B. Watkin, Markus Cornberg, Yuri N. Naumov, John L. Sullivan, Katherine Luzuriaga, Raymond M. Welsh, and Liisa K. Selin

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Eater: a big bite into phagocytosis, Deniz Erturk Hasdemir and Neal S. Silverman

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Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans, Joshua Richard Fischer, Kimberly T. LeBlanc, and John M. Leong

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Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci, Sunita Gulati, Andrew D. Cox, Lisa A. Lewis, Frank St. Michael, Jianjun Li, Ryan Boden, Sanjay Ram, and Peter A. Rice

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Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation, Nicole M. Hermance, Smriti Khurana, Thomas H. Lee, Katherine A. Fitzgerald, and Michelle A. Kelliher

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Interferon gene regulation: not all roads lead to Tolls, Caroline A. Jefferies and Katherine A. Fitzgerald

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Peptidoglycan recognition by the Drosophila Imd pathway, Takashi Kaneko, Douglas T. Golenbock, and Neal S. Silverman

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Bacterial recognition and signalling by the Drosophila IMD pathway, Takashi Kaneko and Neal S. Silverman

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Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion, Carey L. Medin, Katherine A. Fitzgerald, and Alan L. Rothman

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Pro-IL-16 regulation in activated murine CD4+ lymphocytes, Fucheng Ren, Xin Zhan, Gregory W. Martens, Jinhee Lee, David M. Center, Sue Kim Hanson, and Hardy Kornfeld

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The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I, Simon Rothenfusser, Nadege Goutagny, Gary DiPerna, Mei Gong, Brian G. Monks, Annett Schoenemeyer, Masahiro Yamamoto, Shizuo Akira, and Katherine A. Fitzgerald

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HIV-1-specific CD8+ T cell responses and viral evolution in women and infants, Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga

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The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling, Annett Schoenemeyer, Betsy J. Barnes, Margo E. Mancl, Eicke Latz, Nadege Goutagny, Paula M. Pitha, Katherine A. Fitzgerald, and Douglas T. Golenbock

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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence, Julianne Stack, Ismar R. Haga, Martina Schroder, Nathan W. Bartlett, Geraldine Maloney, Patrick Reading, Katherine A. Fitzgerald, Geoffrey L. Smith, and Andrew G. Bowie

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Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex, Hyung S. Youn, Joo Y. Lee, Katherine A. Fitzgerald, Howard A. Young, Shizuo Akira, and Daniel H. Hwang

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Aging of the innate immune response in Drosophila melanogaster, Melissa Zerofsky, Ephat Harel, Neal S. Silverman, and Marc Tatar

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The role of ubiquitination in Drosophila innate immunity, Rui Zhou, Neal S. Silverman, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis

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Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli, Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, Neal S. Silverman, and Bao-Xue Ge

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TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats, Danny Zipris, Egil Lien, Jenny X. Xie, Dale L. Greiner, John P. Mordes, and Aldo A. Rossini

Publications from 2004

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Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells, M.M.M. Abdel-Latif, H. J. Windle, Katherine A. Fitzgerald, Y. S. Ang, D. Ni Eidhin, M. Li-Weber, K. Sabra, and Daniel J. Kelleher

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The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades, Harry Bjorkbacka, Katherine A. Fitzgerald, Francois Huet, Xiaoman Li, James A. Gregory, Melinda Lee, Christine M. Ordija, Nicole E. Dowley, Douglas T. Golenbock, and Mason W. Freeman

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HCMV infection: modulating the cell cycle and cell death, Jonathan Patrick Castillo and Timothy F. Kowalik

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Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors, Gary DiPerna, Julianne Stack, Andrew G. Bowie, Annemarie Boyd, Girish J. Kotwal, Zhouning Zhang, Sheila Arvikar, Eicke Latz, Katherine A. Fitzgerald, and William L. Marshall

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Endotoxin recognition and signal transduction by the TLR4/MD2-complex, Katherine A. Fitzgerald, Daniel C. Rowe, and Douglas T. Golenbock

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Phagocytosis, innate immunity, and host-pathogen specificity, Phillip Henneke and Douglas T. Golenbock

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P504S immunostaining boosts diagnostic resolution of "suspicious" foci in prostatic needle biopsy specimens, Zhong Jiang, Kenneth A. Iczkowski, Bruce A. Woda, Maria S. Tretiakova, and Ximing J. Yang