Publications from 2010
Automated Detection of Infectious Disease Outbreaks in Hospitals: A Retrospective Cohort Study, Susan S. Huang, Deborah S. Yokoe, John Stelling, Hilary Placzek, Martin Kulldorff, Ken Kleinman, Thomas F. O'Brien, Michael S. Calderwood, Johanna Vostok, Julie Dunn, and Richard Platt
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome, Sarah Kim, Franz G. Bauernfeind, Andrea Ablasser, Gunther Hartmann, Katherine A. Fitzgerald, Eicke Latz, and Veit Hornung
Uric acid promotes an acute inflammatory response to sterile cell death in mice, Hajime Kono, Chun-Jen Chen, Fernando Ontiveros, and Kenneth L. Rock
Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts, Oliver Kumpf, Evangelos J. Giamarellos-Bourboulis, Alexander Koch, Lutz Hamann, Maria Mouktaroudi, Djin-Ye Oh, Eicke Latz, Eva Lorenz, David A. Schwartz, Bart Ferwerda, Christina Routsi, Chryssanthi Skalioti, Bart-Jan Kullberg, Jos W. M. van der Meer, Peter M. Schlag, Mihai G. Netea, Kai Zacharowski, and Ralf R. Schumann
Innate recognition of fungal cell walls, Stuart M. Levitz
The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement, Lisa A. Lewis, Jutamas Ngampasutadol, Ruth Wallace, Jane E. A. Reid, Ulrich Vogel, and Sanjay Ram
Detecting microRNA activity from gene expression data, Stephen F. Madden, Susan B. Carpenter, Ian B. Jeffery, Harry Bjorkbacka, Katherine A. Fitzgerald, Luke A. J. O'Neill, and Desmond G. Higgins
Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality, Erica Marchlik, Paresh Thakker, Thaddeus Carlson, Zhaozhao Jiang, Mark Ryan, Suzana Marusic, Nadege Goutagny, Wen Kuang, G. Roger Askew, Victoria Roberts, Stephen Benoit, Tianhui Zhou, Vincent Ling, Richard Pfeifer, Nancy Stedman, Katherine A. Fitzgerald, Lih-Ling Lin, and J. Perry Hall
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4, Edel A. McNeela, Aine Burke, Daniel R. Neill, Cathy Baxter, Vitor E. Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M. McLoughlin, Andres Mori, Barry Moran, Katherine A. Fitzgerald, Jurg Tschopp, Virginie Petrilli, Peter W. Andrew, Aras Kadioglu, and Ed C. Lavelle
Modulation of Exaggerated-IgE Allergic Responses by Gene Transfer-mediated Antagonism of IL-13 and IL-17e., Christian Mueller, Allison M. Keeler, Sofia Braag, Timothy Menz, Qiushi Tang, and Terence R. Flotte
Disorderly conduct in gammadelta versus alphabeta T cell lineage commitment, Kavitha Narayan and Joonso Kang
Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3), Thuy Thanh Nguyen, Ingvild B. Johnsen, Catherine F. Knetter, Finn Drablos, Katherine A. Fitzgerald, Egil Lien, and Marit W. Anthonsen
NOD1 and NOD2 mediate sensing of periodontal pathogens, T. Okugawa, Takashi Kaneko, A. Yoshimura, Neal S. Silverman, and Y. Hara
Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus, Ravichandran Panchanathan, Xin Dua, Hui Shen, Vijay A.K. Rathinam, Loren D. Erickson, Katherine A. Fitzgerald, and Divaker Choubey
Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling, Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, Pascal Meier, and Neal S. Silverman
The use of immunization registry-based data in vaccine effectiveness studies, Hilary Placzek and Lawrence C. Madoff
Prediction of dengue disease severity among pediatric Thai patients using early clinical laboratory indicators, James A. Potts, Robert V. Gibbons, Alan L. Rothman, Anon Srikiatkhachorn, Stephen J. Thomas, Pra-On Supradish, Stephenie C. Lemon, Daniel H. Libraty, Sharone Green, and Siripen Kalayanarooj
Maturation-dependent licensing of naive T cells for rapid TNF production, Bhavana Priyadharshini, Raymond M. Welsh, Dale L. Greiner, Rachel M. Gerstein, and Michael A. Brehm
Inflammasomes and anti-viral immunity, Vijay A.K. Rathinam and Katherine A. Fitzgerald
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses, Vijay A.K. Rathinam, Zhaozhao Jiang, Stephen N. Waggoner, Shrutie Sharma, Leah E. Cole, Lisa Waggoner, Sivapriya Kailasan Vanaja, Brian G. Monks, Sandhya Ganesan, Eicke Latz, Veit Hornung, Stefanie N. Vogel, Eva Szomolanyi-Tsuda, and Katherine A. Fitzgerald
Catenin' on to nucleic acid sensing, Vijay A.K. Rathinam, Shrutie Sharma, and Katherine A. Fitzgerald
Viral defense: it takes two MAVS to Tango, Shrutie Sharma and Katherine A. Fitzgerald
Bi-specific MHC heterodimers for characterization of cross-reactive T cells, Zu T. Shen, Michael A. Brehm, Keith A. Daniels, Alexander B. Sigalov, Liisa K. Selin, Raymond M. Welsh, and Lawrence J. Stern
Structure-guided Design and Immunological Characterization of Immunogens Presenting the HIV-1 gp120 V3 Loop on a CTB Scaffold, Maxim Totrov, Xunqing Jiang, Xiang-Peng Kong, Sandra cohen, Chavdar Krachmarov, Constance Williams, Michael S. Seaman, Timothy Cardozo, Miroslaw K. Gorny, Shixia Wang, Shan Lu, Abraham Pinter, and Susan Zolla-Pazner
Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin, Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, Neal S. Silverman, and Margaret J. McFall-Ngai
IFI16 is an innate immune sensor for intracellular DNA, Leonie Unterholzner, Sinead E. Keating, Marcin Baran, Kristy A. Horan, Soren B. Jensen, Shrutie Sharma, Cherilyn M. Sirois, Tengchuan Jin, Eicke Latz, T. Sam Xiao, Katherine A. Fitzgerald, Soren R. Paludan, and Andrew G. Bowie
Profiles of human serum antibody responses elicited by three leading HIV vaccines focusing on the induction of Env-specific antibodies, Michael Vaine, Shixia Wang, Qin Liu, James Arthos, David C. Montefiori, Paul Goepfert, M. Juliana McElrath, and Shan Lu
Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling, Allison L. van Lint, Matthew R. Murawski, Rory E. Goodbody, Martina Severa, Katherine A. Fitzgerald, Robert W. Finberg, David M. Knipe, and Evelyn A. Kurt-Jones
Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis, Stephen N. Waggoner, Ruth T. Taniguchi, Porunelloor A. Mathew, Vinay Kumar, and Raymond M. Welsh
TLR4 is a negative regulator in noninfectious lung inflammation, Hang Zhao, Shaw-Wei Leu, Liyun Shi, Rejmon Dedaj, Gaofeng Zhao, Hari G. Garg, Lianjun Shen, Egil Lien, Katherine A. Fitzgerald, Aviva Shiedlin, Huahao Shen, Deborah A. Quinn, and Charles A. Hales
Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus, Shenghua Zhou, Anna M. Cerny, An Zacharia, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, and Robert W. Finberg
Publications from 2009
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate, Andrea Ablasser, Franz G. Bauernfeind, Gunther Hartmann, Eicke Latz, Katherine A. Fitzgerald, and Veit Hornung
Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes, Andrea Ablasser, Hendrik Poeck, David Anz, Michael Berger, Martin Schlee, Sarah Kim, Carole Bourquin, Nadege Goutagny, Zhaozhao Jiang, Katherine A. Fitzgerald, Simon Rothenfusser, Stefan Endres, Gunther Hartmann, and Veit Hornung
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression, Franz G. Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S. Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G. Monks, Katherine A. Fitzgerald, Veit Hornung, and Eicke Latz
Molecular mechanisms involved in inflammasome activation, Clare Bryant and Katherine A. Fitzgerald
Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling, Leah E. Cole, Michelle H.W. Laird, Anna Seekatz, Araceli Santiago, Zhaozhao Jiang, Eileen Barry, Kari Ann Shirey, Katherine A. Fitzgerald, and Stefanie N. Vogel
In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses, Mary Dawn T. Co, Laura Orphin, John Cruz, Pamela P. Pazoles, Karin M. Green, James A. Potts, Anita M. Leporati, Jenny Aurielle B. Babon, James E. Evans, Francis A. Ennis, and Masanori Terajima
Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes, Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paul Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, Pascal Meier, and Neal S. Silverman
Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo, Martin Felices, Catherine C. Yin, Yoko Kosaka, Joonsoo Kang, and Leslie J. Berg
Integr-ating IL-1 alpha in antiviral host defenses, Katherine A. Fitzgerald
Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection, Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Neal S. Silverman, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans, Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan, Krupen Patel, Brian A. Hall, Gordon D. Brown, and Katherine A. Fitzgerald
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC, Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz G. Bauernfeind, Gabor Horvath, Daniel R. Caffrey, Eicke Latz, and Katherine A. Fitzgerald
Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists, Haibin Huang, Gary R. Ostroff, Chrono K. Lee, Jennifer P. Wang, Charles A. Specht, and Stuart M. Levitz
Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice, Smita Jaiswal, Todd Pearson, Heather Friberg, Leonard D. Shultz, Dale L. Greiner, Alan L. Rothman, and Anuja Mathew
The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling, Ingvild B. Johnsen, Thuy Thanh Nguyen, Bjarte Bergstroem, Katherine A. Fitzgerald, and Marit W. Anthonsen
Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus, Sybille Kenzel, Sandra Santos-Sierra, Sachin D. Deshmukh, Inga Moeller, Bilge Ergin, Katherine A. Fitzgerald, Egil Lien, Shizuo Akira, Douglas T. Golenbock, and Phillip Henneke
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP, Sarah M. McWhirter, Roman Barbalat, Kathryn M. Monroe, Mary F. Fontana, Mamoru Hyodo, Nathalie T. Joncker, Ken J. Ishii, Shizuo Akira, Marco Colonna, Zhiliang Cheng, Katherine A. Fitzgerald, Yoshihiro Hayakawa, and Russell E. Vance
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR, Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran
TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade, David M. Miller, Thomas B. Thornley, Todd Pearson, Annie J. Kruger, Masahiro Yamazaki, Leonard D. Shultz, Raymond M. Welsh, Michael A. Brehm, Aldo A. Rossini, and Dale L. Greiner
A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling, Kamalpreet Nagpal, Theo S. Plantinga, Joyce Wong, Brian G. Monks, Nicholas J. Gay, Mihai G. Netea, Katherine A. Fitzgerald, and Douglas T. Golenbock
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis, Amit K. Pandey, Yibin Yang, Zhaozhao Jiang, Sarah M. Fortune, Francois Coulombe, Marcel A. Behr, Katherine A. Fitzgerald, Christopher M. Sassetti, and Michelle A. Kelliher
Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling, Wenji Piao, Chang Song, Haiyan Chen, Marco A. Quevedo Diaz, Larry M. Wahl, Katherine A. Fitzgerald, Liwu Li, and Andrei E. Medvedev
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus, Martin Schlee, Andreas Roth, Veit Hornung, Christina Amparo Hagmann, Vera Wimmenauer, Winfried Barchet, Christoph Coch, Markus Janke, Aleksandra Mihailovic, Greg Wardle, Stefan Juranek, Hiroki Kato, Taro Kawai, Hendrik Poeck, Katherine A. Fitzgerald, Osamu Takeuchi, Shizuo Akira, Thomas Tuschl, Eicke Latz, Janos Ludwig, and Gunther Hartmann
Novel mechanistic insights into viral modulation of immune receptor signaling, Alexander B. Sigalov
Specificity and Signaling in the Drosophila Immune Response, Neal S. Silverman, Nicholas Paul Paquette, and Kamna Aggarwal
Topographic analysis of individual activation patterns in medial frontal cortex in schizophrenia, Emily R. Stern, Robert C. Welsh, Katherine A. Fitzgerald, and Stephan F. Taylor
Inflammasomes: too big to miss, Andrea Stutz, Douglas T. Golenbock, and Eicke Latz
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K, Yu Sun, Minako Ishibashi, Tracie Seimon, Mingsum Lee, Sudarshana M. Sharma, Katherine A. Fitzgerald, Andriy O. Samokhin, Yibin Wang, Scott Sayers, Masanori Aikawa, W. Gray Jerome, Michael C. Ostrowski, Dieter Bromme, Peter Libby, Ira A. Tabas, Carrie L. Welch, and Alan R. Tall
Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis, Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paul Paquette, Neal S. Silverman, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai
Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling, Connie W. Woo, Dongying Cui, Jerry Arellano, Bernhard Dorweiler, Heather Harding, Katherine A. Fitzgerald, David Ron, and Ira Tabas
Publications from 2008
Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway, Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, Nicholas Paquette, and Neal S. Silverman
Positive and negative regulation of the Drosophila immune response, Kamna Aggarwal and Neal S. Silverman
Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination, Mumtaz Yaseen Balkhi, Katherine A. Fitzgerald, and Paula M. Pitha
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi, Daniella C. Bartholomeu, Catherine Ropert, Mariane B. Melo, Peggy Parroche, Caroline F. Junqueira, Santuza M. R. Teixeira, Cherilyn M. Sirois, Pia Kasperkovitz, Cathrine F. Knetter, Egil Lien, Eicke Latz, Douglas T. Golenbock, and Ricardo T. Gazzinelli
TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA, Marie Charrel-Dennis, Eicke Latz, Kristen A. Halmen, Patrick Trieu-Cuot, Katherine A. Fitzgerald, Dennis L. Kasper, and Douglas T. Golenbock
A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts, Anne-Danielle C. Chessler, Ludmila R. Ferreira P., Tun-Han Chang, Katherine A. Fitzgerald, and Barbara A. Burleigh
Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens, Karim C. El Kasmi, Joseph E. Qualls, John T. Pesce, Amber M. Smith, Robert W. Thompson, Marcela Henao-Tamayo, Randall J. Basaraba, Till Konig, Ulrike Schleicher, Mi-Sun Koo, Gilla Kaplan, Katherine A. Fitzgerald, Elaine I. Tuomanen, Ian M. Orme, Thirumala-Devi Kanneganti, Christian Bogdan, Thomas A. Wynn, and Peter J. Murray
Hormonal regulation of the humoral innate immune response in Drosophila melanogaster, Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, Marc Tatar, and Neal S. Silverman
Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling, Felix Geeraedts, Nadege Goutagny, Veit Hornung, Martina Severa, Aalzen de Haan, Judity Pool, Jan Wilschut, Katherine A. Fitzgerald, and Anke Huckriede
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta, Annett Halle, Veit Hornung, Gabor C. Petzold, Cameron R. Stewart, Brian G. Monks, Thomas Reinheckel, Katherine A. Fitzgerald, Eicke Latz, Kathryn J. Moore, and Douglas T. Golenbock
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3, Rowan Higgs, Joan Ni Gabhann, Nadia Ben Larbi, Eamon P. Breen, Katherine A. Fitzgerald, and Caroline A. Jefferies
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization, Veit Hornung, Franz G. Bauernfeind, Annett Halle, Eivind O. Samstad, Hajime Kono, Kenneth L. Rock, Katherine A. Fitzgerald, and Eicke Latz
Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein, Xueqiao Liu, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, Robert W. Finberg, and David M. Knipe
Engineered intermonomeric disulfide bonds in the globular domain of Newcastle disease virus hemagglutinin-neuraminidase protein: implications for the mechanism of fusion promotion, Paul J. Mahon, Anne M. Mirza, Thomas A. Musich, and Ronald M. Iorio
Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virus, Anuja Mathew, Joel M. O'Bryan, William L. Marshall, Girish J. Kotwal, Masanori Terajima, Sharone Green, Alan L. Rothman, and Francis A. Ennis
Role of innate immunity in transplantation tolerance., David M. Miller, Aldo A. Rossini, and Dale L. Greiner
Viral infection: a potent barrier to transplantation tolerance, David M. Miller, Thomas B. Thornley, Dale L. Greiner, and Aldo A. Rossini
TLR agonists abrogate co-stimulation blockade-induced mixed chimerism and transplantation tolerance., David M. Miller, Thomas B. Thornley, Todd Pearson, Masahiro Yamazaki, Michael A. Brehm, Aldo A. Rossini, and Dale L. Greiner
Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response, Andrea Paun, Jorgen T. Reinert, Zhaozhao Jiang, Carey L. Medin, Mumtaz Yaseen Balkhi, Katherine A. Fitzgerald, and Paula M. Pitha
Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment, Todd Pearson, Leonard D. Shultz, David M. Miller, Marie A. King, Joseph Laning, William Fodor, Amy Cuthbert, Lisa M. Burzenski, Bruce Gott, Bonnie L. Lyons, Oded Foreman, Aldo A. Rossini, and Dale L. Greiner
Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance, Wenji Piao, Chang Song, Haiyan Chen, Larry M. Wahl, Katherine A. Fitzgerald, Luke A. J. O'Neill, and Andrei E. Medvedev
Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA, Zaida G. Ramirez-Ortiz, Charles A. Specht, Jennifer P. Wang, Chrono K. Lee, Daniella C. Bartholomeu, Ricardo T. Gazzinelli, and Stuart M. Levitz
Immunogenicity and protection efficacy of subunit-based smallpox vaccines using variola major antigens, Pavlo V. Sakhatskyy, Shixia Wang, Chuanyou Zhang, Te-Hui Chou, Michael G. Kishko, and Shan Lu
Immunology. The right resident bugs, Neal S. Silverman and Nicholas Paul Paquette
Hepatitis C and innate immunity: recent advances, Gyongyi Szabo and Angela Dolganiuc
Improved induction of antibodies against key neutralizing epitopes by HIV-1 gp120 DNA prime-protein boost vaccination compared to gp120 protein only vaccination, Michael Vaine, Shixia Wang, Emma T. Crooks, Pengfei Jiang, David C. Montefiori, James Binley, and Shan Lu
Cryptococcus neoformans enters the endolysosomal pathway of dendritic cells and is killed by lysosomal components, Karen L. Wozniak and Stuart M. Levitz
Autophagic control of listeria through intracellular innate immune recognition in drosophila, Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Neal S. Silverman, Tamotsu Yoshimori, and Shoichiro Kurata
Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses, Shenghua Zhou, Annett Halle, Evelyn A. Kurt-Jones, Anna M. Cerny, Ermelinda Porpiglia, Michael Rogers, Douglas Golenbock, and Robert W. Finberg
Publications from 2007
Peptidoglycan recognition in Drosophila, Kamna Aggarwal and Neal S. Silverman
RIG-I: tri-ing to discriminate between self and non-self RNA, Andrew G. Bowie and Katherine A. Fitzgerald
Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif, Pamela Cook, Sabine Totemeyer, Catherine Stevenson, Katherine A. Fitzgerald, Masahiro Yamamoto, Shizuo Akira, Duncan J. Maskell, and Clare E. Bryant
Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster, Deniz Erturk Hasdemir, Nicholas Paul Paquette, Kamna Aggarwal, and Neal S. Silverman
Immunology. The shape of things to come, Katherine A. Fitzgerald and Douglas T. Golenbock
CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help, Maria Genevieve H. Hernandez, Lianjun Shen, and Kenneth L. Rock
Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM, Amy G. Hise, Katrin Daehnel, Illona Gillette-Ferguson, Eun Cho, Helen F. McGarry, Mark J. Taylor, Douglas T. Golenbock, Katherine A. Fitzgerald, James W. Kazura, and Eric Pearlman
Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity, Marie A. King, Todd Pearson, Leonard D. Shultz, Jean H. Leif, Rita Bottino, Massimo Trucco, Mark A. Atkinson, Clive Wasserfall, Kevan C. Herold, John P. Mordes, Aldo A. Rossini, and Dale L. Greiner
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene, Marie A. King, Todd Pearson, Leonard D. Shultz, Jean H. Leif, Rita Bottino, Massimo Trucco, Mark A. Atkinson, Clive Wasserfall, Kevan C. Herold, Robert T. Woodland, Madelyn R. Schmidt, Bruce A. Woda, Michael J. Thompson, Aldo A. Rossini, and Dale L. Greiner
Ligand-induced conformational changes allosterically activate Toll-like receptor 9, Eicke Latz, Anjali Verma, Alberto Visintin, Mei Gong, Cherilyn M. Sirois, Dionne C. G. Klein, Brian G. Monks, C. James McKnight, Marc S. Lamphier, W. Paul Duprex, Terje Espevik, and Douglas T. Golenbock