Immunology. The shape of things to come
Department of Medicine, Division of Infectious Diseases and Immunology
Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; *Adjuvants, Immunologic; Animals; Crystallography, X-Ray; Glycolipids; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Lipid A; Lymphocyte Activation; Lymphocyte Antigen 96; Mice; Phosphates; Protein Conformation; Receptors, Interleukin; Signal Transduction; T-Lymphocytes; Toll-Like Receptor 4
Mechanistic understanding of how ligands can fine-tune the immune response may lead to better vaccine adjuvants.
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Citation: Science. 2007 Jun 15;316(5831):1574-6. Link to article on publisher's site
Fitzgerald, Katherine A. and Golenbock, Douglas T., "Immunology. The shape of things to come" (2007). Infectious Diseases and Immunology Publications and Presentations. 81.