Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity

UMMS Affiliation

Center for Infectious Disease and Vaccine Research; Department of Medicine, Division of Infectious Diseases and Immunology

Publication Date


Document Type



Immunity | Immunology and Infectious Disease | Immunology of Infectious Disease | Infectious Disease | Medical Immunology | Virology


The goal of this study was to investigate further the role of Th1 cytokines, such as IL-12, and that of counterregulatory Th2 cytokines, such as IL-10, to fur- ther elucidate the possible immunological mechanisms responsible for the development of the plasma leakage seen in dengue hemorrhagic fever.

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Citation: J Med Virol. 1999 Nov;59(3):329-34. doi:10.1002/(SICI)1096-9071(199911)59:3<329::AID-JMV12>3.0.CO;2-G

Journal/Book/Conference Title

Journal of medical virology

Related Resources

Link to Article in PubMed

PubMed ID