NIAID workshop on Flavivirus immunity
Center for Infectious Disease and Vaccine Research; Division of Infectious Diseases and Immunology, Department of Medicine
On September 16, 2009, the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National Institutes of Health, convened a workshop to discuss current knowledge of T- and B-cell immune epitopes for members of the Flavivirus genus (family Flaviviridae), and how this information could be used to increase our basic understanding of host-pathogen interactions and/or advance the development of new or improved vaccines and diagnostics for these pathogens. B-cell and T-cell responses to flaviviruses are critical components of protective immunity against these pathogens. However, they have also been linked to disease pathogenesis. A detailed understanding of the biological significance of immune epitope information may provide clues regarding the mechanisms governing the induction of protective versus pathogenic adaptive immune responses.
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Citation: Viral Immunol. 2010 Jun;23(3):235-40. doi: 10.1089/vim.2009.0114. Link to article on publisher's site
Augustine, Alison D.; Cassetti, M Cristina.; Ennis, Francis A.; Harris, Eva; Hildebrand, William H.; and Repik, Patricia M., "NIAID workshop on Flavivirus immunity" (2010). Infectious Diseases and Immunology Publications and Presentations. 240.