Title

NIAID workshop on Flavivirus immunity

UMMS Affiliation

Center for Infectious Disease and Vaccine Research; Division of Infectious Diseases and Immunology, Department of Medicine

Publication Date

6-1-2010

Document Type

Article

Disciplines

Immunity | Immunology and Infectious Disease | Immunology of Infectious Disease | Infectious Disease

Abstract

On September 16, 2009, the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National Institutes of Health, convened a workshop to discuss current knowledge of T- and B-cell immune epitopes for members of the Flavivirus genus (family Flaviviridae), and how this information could be used to increase our basic understanding of host-pathogen interactions and/or advance the development of new or improved vaccines and diagnostics for these pathogens. B-cell and T-cell responses to flaviviruses are critical components of protective immunity against these pathogens. However, they have also been linked to disease pathogenesis. A detailed understanding of the biological significance of immune epitope information may provide clues regarding the mechanisms governing the induction of protective versus pathogenic adaptive immune responses.

Rights and Permissions

Citation: Viral Immunol. 2010 Jun;23(3):235-40. doi: 10.1089/vim.2009.0114. Link to article on publisher's site

Journal/Book/Conference Title

Viral immunology

Related Resources

Link to Article in PubMed

PubMed ID

20565288