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<channel>
<title>Center for Health Policy and Research (CHPR) Publications and Presentations</title>
<copyright>Copyright (c) 2013 University of Massachusetts Medical School All rights reserved.</copyright>
<link>http://escholarship.umassmed.edu/healthpolicy_pp</link>
<description>Recent documents in Center for Health Policy and Research (CHPR) Publications and Presentations</description>
<language>en-us</language>
<lastBuildDate>Sun, 10 Mar 2013 01:37:04 PST</lastBuildDate>
<ttl>3600</ttl>


	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	

	
		
	




<item>
<title>Determinants of mammography in women with intellectual disabilities</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/139</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/139</guid>
<pubDate>Fri, 08 Mar 2013 10:38:41 PST</pubDate>
<description>
	<![CDATA[
	<p>BACKGROUND: Women with intellectual disabilities have the same rate of breast cancer as other women but are less likely to undergo screening mammography. Characteristics associated with mammography for women with intellectual disabilities in the United States are unknown.</p>
<p>METHODS: This study was based on a secondary data analysis of the Massachusetts Department of Developmental Services database, comparing women who had a mammogram within 2 years with women who had not on variables related to the ecological model. Bivariate analyses, logistic regression, and assessment of interactions were performed.</p>
<p>RESULTS: The study sample's (n = 2907) mean age was 54.7 years; 58% lived in 24-hour residential settings, 52% received nursing health coordination, and more than 25% had clinical examination needs (eg, sedation). Residential setting, health coordination, and recent influenza vaccination were all associated with mammography. Having a guardian, higher level of activities of daily living needs, and examination needs (requiring sedation or limited wait time for examinations) were associated with lower rates. Interactions between health coordination and examination needs confirmed the potential of the nurse to ameliorate barriers to mammography.</p>
<p>CONCLUSION: Several system-level variables were significantly associated with mammography and, in some cases, seemed to ameliorate intrapersonal/behavioral barriers to mammography. Community agencies caring for intellectually disabled women have potential to impact mammography rates by using health coordination.</p>

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</description>

<author>Joanne E. Wilkinson et al.</author>


<category>Activities of Daily Living</category>

<category>Adult</category>

<category>Aged</category>

<category>Breast Neoplasms</category>

<category>Early Detection of Cancer</category>

<category>Female</category>

<category>Health Services Accessibility</category>

<category>Humans</category>

<category>Intellectual Disability</category>

<category>Logistic Models</category>

<category>Mammography</category>

<category>Massachusetts</category>

<category>Middle Aged</category>

<category>Multivariate Analysis</category>

<category>Patient-Centered Care</category>

<category>Residential Facilities</category>

</item>




<item>
<title>Weight loss following a clinic-based weight loss program among adults with attention deficit/hyperactivity disorder symptoms</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/138</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/138</guid>
<pubDate>Fri, 08 Mar 2013 09:16:51 PST</pubDate>
<description>
	<![CDATA[
	<p>OBJECTIVE: The purpose of the present study was to compare obese patients screening positive or negative for attention deficit/hyperactivity disorder (ADHD) on pretreatment body mass index (BMI), weight loss following a 16 week clinic-based behavioral weight loss program, weight loss attempts, dietary and physical activity habits, perceived difficulty of weight control skills, and eating self-efficacy.</p>
<p>DESIGN: Patients who completed a behavioral weight loss program were approached to complete questionnaires on ADHD and eating habits. Medical charts were reviewed to obtain weight at pre- and post-treatment.</p>
<p>RESULTS: Participants (N=63) were 75% female, mean age was 49 (SD=10.3), mean body mass index (BMI) was 41.4 kg/m² (SD=6.8) and 30% screened positive for ADHD on the Adult ADHD Symptom Rating Scale. Participants screening positive for ADHD did not have a higher BMI at baseline (p=0.41), but reported more previous weight loss attempts (p=0.01) and lost less weight (p=0.02) than participants who screened negative. Participants screening positive also reported consuming fast food meals more frequently (p=0.04), higher levels of emotional eating (p=0.002), greater difficulty with weight control skills (p=0.01), and lower eating self-efficacy (p=0.001).</p>
<p>CONCLUSION: Attention-related problems appear to be common among weight treatment-seeking samples and represent a significant barrier to weight control that has not yet been addressed in the literature.</p>

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</description>

<author>Sherry L. Pagoto et al.</author>


<category>Adult</category>

<category>Attention Deficit Disorder with Hyperactivity</category>

<category>Body Mass Index</category>

<category>Body Weight</category>

<category>Diet Therapy</category>

<category>Exercise Therapy</category>

<category>Feeding Behavior</category>

<category>Female</category>

<category>Health Promotion</category>

<category>Humans</category>

<category>Middle Aged</category>

<category>Obesity</category>

<category>Questionnaires</category>

<category>Self Efficacy</category>

</item>




<item>
<title>Preliminary Exploration of the Effect of Background Color on the Speed and Accuracy of Search for an Aided Symbol Target by Typically Developing Preschoolers</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/137</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/137</guid>
<pubDate>Fri, 08 Mar 2013 09:16:50 PST</pubDate>
<description>
	<![CDATA[
	<p>Aided augmentative and alternative communication can be used successfully with individuals with communication disabilities. Recent studies suggest that, where possible, arranging symbols based on internal color (placing red fruits together) facilitates search for a target symbol by children with and without Down syndrome (Wilkinson, Carlin, & Thistle, 2008). We explored whether color cuing of symbol background might offer similar benefits for symbols that cannot readily be arranged by internal color. Ten nondisabled preschoolers engaged in computer search tasks for line drawings representing common animals when the line drawings appeared on white backgrounds compared to color-saturated backgrounds that cued the subcategory to which the target belonged (land mammal, sea creature, bird, insect). Older children showed no consistent enhancement across conditions. Younger children responded significantly more slowly when the color cue was present. Background color cuing may function differently than symbol-internal color cues, impeding responses in younger children rather than facilitating them.</p>

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</description>

<author>Krista M. Wilkinson et al.</author>


<category>Communication Disorders</category>

<category>Down Syndrome</category>

<category>Communication Aids for Disabled</category>

<category>Color Perception</category>

<category>Child, Preschool</category>

</item>




<item>
<title>Comprehension by design: Teaching young learners how to comprehend what they read</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/136</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/136</guid>
<pubDate>Fri, 08 Mar 2013 09:16:49 PST</pubDate>
<description>
	<![CDATA[
	<p>Teaching learners how to comprehend text remains a largely unsuccessful attempt in our school system. Drawing from the fields of learning sciences, education, instructional design, and performance improvement, we designed, tested, revised, and released to schools and homes an interactive online program that reliably teaches flexible, widely applicable reading comprehension strategies to children. This article describes the analysis and design processes involved in the development of such a program.</p>

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</description>

<author>Marta Leon et al.</author>


<category>Reading</category>

<category>Comprehension</category>

</item>




<item>
<title>Attention Deficit/Hyperactivity Disorder and the Clinical Management of Obesity</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/135</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/135</guid>
<pubDate>Fri, 08 Mar 2013 09:16:48 PST</pubDate>
<description>
	<![CDATA[
	<p>Attention deficit/hyperactivity disorder (ADHD) has been associated with increased risk for obesity and obesity treatment failure. The present paper discusses how features of ADHD, including inattention, reward sensitivity, and impulsivity, may impact obesity risk and have implications for the management of obesity. In addition, we review emerging research on how obesity may contribute to brain changes that are associated with ADHD-like symptoms. Finally, suggestions for improving the clinical management of obesity in patients with ADHD are discussed, including pharmacological treatment, exercise, and cognitive behavior therapy. ADHD is a barrier to the clinical management of obesity and more research is needed to further understand the link between ADHD and obesity. Effective treatment approaches are needed given the significant difficulty patients with ADHD encounter in their attempts to regulate their weight in the context of an obesogenic environment.</p>

	]]>
</description>

<author>Sherry L. Pagoto et al.</author>


<category>Attention Deficit Disorder with Hyperactivity</category>

<category>Obesity</category>

</item>




<item>
<title>Acoustic stapedius muscle reflex in mercury-exposed Andean children and adults</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/134</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/134</guid>
<pubDate>Fri, 08 Mar 2013 09:16:47 PST</pubDate>
<description>
	<![CDATA[
	<p>OBJECTIVES: Hg exposure has been associated with hearing impairment and brainstem anomalies. Acoustic stapedius reflex (ASR) thresholds, growth functions, decay/adaptation times, and behavioral auditory thresholds were used to screen Andean children and adults for Hg-induced auditory brainstem and facial nerve impairment.</p>
<p>METHODS: Fifty-one participants, which included 22 children (aged 6-17 years) and 29 adults (aged 19-83 years) living in gold mining areas of Ecuador where Hg is widely used in amalgamation, were screened using ASR immittance procedures.</p>
<p>RESULTS: Mean blood mercury (HgB) level in the children was 15.6 mug/L (SD, 21.3; median, 7 mug/L; range, 2.0-89 mug/L), and in the adults 8.5 mug/L (SD, 7.1; median, 6 mug/L; range, 2.0-32 mug/L). Mean contralateral ASR thresholds (ASRT) for the screening frequency of 2000 Hz in the children (39 ears) was 92.9 dB HL (SD, 6.1; range, 80-105 dB HL), and in the adults (53 ears) 90.0 dB HL (SD, 6.4; range, 65-105 dB HL). The ASRT in the children increased significantly with HgB level (rho = 0.433; p = 0.008).</p>
<p>CONCLUSION: The results suggested mercury (Hg)-induced anomalies in the brainstem-mediated acoustic stapedius muscle reflex in children.</p>

	]]>
</description>

<author>S. Allen Counter et al.</author>


<category>Adolescent</category>

<category>Adult</category>

<category>Aged</category>

<category>Aged, 80 and over</category>

<category>Auditory Threshold</category>

<category>Child</category>

<category>Ecuador</category>

<category>Environmental Exposure</category>

<category>Environmental Illness</category>

<category>Evoked Potentials, Auditory, Brain Stem</category>

<category>Female</category>

<category>Humans</category>

<category>Incidence</category>

<category>Male</category>

<category>Mercury</category>

<category>Middle Aged</category>

<category>*Mining</category>

<category>Reflex, Acoustic</category>

<category>Young Adult</category>

</item>




<item>
<title>Assessment of auditory brainstem function in lead-exposed children using stapedius muscle reflexes</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/133</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/133</guid>
<pubDate>Fri, 08 Mar 2013 09:16:46 PST</pubDate>
<description>
	<![CDATA[
	<p>The purpose of this study was to investigate the neurological integrity and physiological status of the auditory brainstem tracts and nuclei in children with chronic lead (Pb) exposure using non-invasive acoustic stapedius reflex (ASR) measurements of afferent and efferent-neuromuscular auditory function. Following audiological examinations, uncrossed (ipsilateral) and crossed (contralateral) brainstem ASR responses were evoked by pure tone (500, 1000, and 2000 Hz), and broadband noise (bandwidth: 125-4000 Hz) stimulus activators. The ASR threshold (ASRT), amplitude growth, and decay/fatigue were measured by conventional clinical middle ear immittance methods in a group of Andean children (age range: 2-18 years) with a history of chronic environmental Pb exposure from occupational Pb glazing. Blood lead (PbB) levels of the study group (n=117) ranged from 4.0 to 83.7 mug/dL with a mean PbB level of 33.5 mug/dL (SD: 23.6; median: 33.0: CDC III Classification). The PbB distribution data indicated that 77.8% (n=91) of the children had PbB levels greater than the CDC action line of 10 mug/dL. Repeatable, normal ASRTs were elicited for ipsilateral (mean:</p>

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</description>

<author>S. Allen Counter et al.</author>


<category>Acoustic Stimulation</category>

<category>Adolescent</category>

<category>Child</category>

<category>Child, Preschool</category>

<category>Ecuador</category>

<category>Environmental Exposure</category>

<category>Evoked Potentials, Auditory, Brain Stem</category>

<category>Female</category>

<category>Functional Laterality</category>

<category>Humans</category>

<category>Lead</category>

<category>Lead Poisoning</category>

<category>Male</category>

<category>Psychoacoustics</category>

<category>Reflex, Acoustic</category>

<category>Stapedius</category>

</item>




<item>
<title>Changing the landscape of autism research: the autism genetic resource exchange</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/132</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/132</guid>
<pubDate>Fri, 08 Mar 2013 09:16:46 PST</pubDate>
<description>
	<![CDATA[
	<p>Autism Speaks' Autism Genetic Resource Exchange (AGRE) represents the largest private collection of genetic and phenotype data for families with ASD that is made available to qualified researchers worldwide. The availability of large and comprehensive registries that include detailed phenotype and genetic information for individuals affected with an ASD and family members is crucial for the discovery of autism susceptibility genes and the development and application of biologically based approaches to diagnosis and treatment. The model that AGRE has developed can be applied broadly to other disorders with complex etiologies.</p>

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</description>

<author>Clara M. Lajonchere et al.</author>


<category>Autistic Disorder</category>

<category>Biomedical Research</category>

<category>*Computational Biology</category>

<category>*Genetic Predisposition to Disease</category>

<category>Humans</category>

<category>*Information Dissemination</category>

</item>




<item>
<title>Commentary: the art of forensic report writing</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/131</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/131</guid>
<pubDate>Fri, 08 Mar 2013 09:16:45 PST</pubDate>
<description>
	<![CDATA[
	<p>As forensic psychiatry has matured into a well-recognized subspecialty, considerable agreement about the format and content of reports has emerged. Griffith et al. now turn their attention to the art of forensic writing. Their description of the forensic report as "performative narrative" may help to refine professional practice so long as the ethics-related pitfalls are identified and avoided.</p>

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</description>

<author>Kenneth L. Appelbaum</author>


<category>*Expert Testimony</category>

<category>Forensic Psychiatry</category>

<category>Humans</category>

<category>*Narration</category>

<category>*Writing</category>

</item>




<item>
<title>Comparison of physical activity between children with autism spectrum disorders and typically developing children</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/130</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/130</guid>
<pubDate>Fri, 08 Mar 2013 09:16:44 PST</pubDate>
<description>
	<![CDATA[
	<p>Regular physical activity is important for promoting health and well-being; however, physical activity behaviors in children with autism spectrum disorders (ASD) have received little attention. We compared physical activity levels among 53 children with ASD and 58 typically developing children aged 3-11 years who participated in the Children's Activity and Meal Patterns Study (CHAMPS). After adjustment for age and sex the amount of time spent daily in moderate and vigorous activity was similar in children with ASD (50.0 minutes/day and typically developing children 57.1 minutes/day). However, parents reported that children with ASD participated in significantly fewer types of physical activities than did typically developing children (6.9 vs. 9.6, p</p>

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</description>

<author>Linda G. Bandini et al.</author>


<category>Child Development Disorders, Pervasive</category>

<category>Motor Activity</category>

</item>




<item>
<title>Dating Violence and Associated Health Risks Among High School Students with Disabilities</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/128</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/128</guid>
<pubDate>Fri, 08 Mar 2013 09:16:43 PST</pubDate>
<description>
	<![CDATA[
	<p>Children with disabilities are at a higher risk for various forms of violence including sexual violence, bullying, and physical violence compared to those without disabilities. However there are no studies documenting the prevalence of dating violence amongst a population-based sample of adolescents with disabilities. The purpose of this study is to assess the prevalence of dating violence victimization against high schools students with and without disabilities and to examine associations of dating violence with health risks by disability status among high school girls. Data from the 2009 Massachusetts Youth Health Survey were analyzed in 2011 using bivariate and multivariate logistic regression. Among high school students who had ever been on a date, girls (25.9 %, 95 % CI 19.9-31.5) and boys (9.1 %, 95 % CI 5.8-12.4) with disabilities were more likely than girls (8.8 %, 95 % CI 6.8-10.8) and boys (4.5 %, 95 % CI 3.1-5.8) without disabilities to report dating violence. Multivariate analyses indicated that high school girls with disabilities who experienced dating violence were more likely to report feeling sad or hopeless for 2 weeks or more in the past year, suicide ideation in the past 12 months, and drug use in the past 30 days compared to those with disabilities who did not report dating violence and those without disabilities who reported and did not report dating violence. High school students with disabilities are at a greater risk for dating violence victimization compared to those without disabilities and high school girls with disabilities who experience dating violence are at increased risk for experiencing poor mental health outcomes and substance abuse.</p>

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</description>

<author>Monika Mitra et al.</author>


<category>Sex Offenses</category>

<category>Violence</category>

<category>Adolescent</category>

<category>Students</category>

<category>Disabled Children</category>

</item>




<item>
<title>Contextual influences on resistance to disruption in children with intellectual disabilities</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/129</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/129</guid>
<pubDate>Fri, 08 Mar 2013 09:16:43 PST</pubDate>
<description>
	<![CDATA[
	<p>Training context can influence resistance to disruption under differing reinforcement schedules. With nonhumans, when relatively lean and rich reinforcement schedules are experienced in the context of a multiple schedule, greater resistance is found in the rich than the lean component, as described by behavioral momentum theory. By contrast, when the schedules are experienced in separated blocks of sessions (i.e., as single schedules), resistance is not consistently greater in either component. In the current study, two groups of 6 children with intellectual disabilities responded to stimuli presented in relatively lean or rich components. For both, reinforcers were delivered according to the same variable-interval reinforcement schedule; additionally, the rich component included the delivery of response-independent reinforcers. The Within group was trained on a multiple schedule in which lean and rich components alternated regularly within sessions; the Blocked group was trained on two single schedules in which sessions with either the lean or rich schedule were conducted in successive blocks. Disruption tests presented a concurrently available alternative stimulus disrupter signaling the availability of tangible reinforcers. All 6 Within participants showed greater resistance to disruption in the rich component, consistent with behavioral momentum theory. By contrast, there was no consistent or significant difference in resistance for Blocked participants. This finding is potentially relevant to the development of interventions in applied settings, where such interventions often approximate single schedules and include response-independent reinforcers.</p>

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</description>

<author>Karen M. Lionello-DeNolf et al.</author>


<category>Adolescent</category>

<category>Child</category>

<category>Discrimination (Psychology)</category>

<category>Education of Intellectually Disabled</category>

<category>Female</category>

<category>Humans</category>

<category>Intellectual Disability</category>

<category>Male</category>

<category>*Reinforcement (Psychology)</category>

<category>Reinforcement Schedule</category>

<category>Young Adult</category>

</item>




<item>
<title>Detection of retinoic acid catabolism with reporter systems and by in situ hybridization for CYP26 enzymes</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/127</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/127</guid>
<pubDate>Fri, 08 Mar 2013 09:16:42 PST</pubDate>
<description>
	<![CDATA[
	<p>Retinoic acid (RA), an active form of vitamin A, is essential for life in vertebrates, owing to its capacity of influencing expression of a sizable fraction of all genes and proteins. It functions via two modes: (1) as controlling ligand for specific transcription factors in the nucleus it stimulates or inhibits gene expression from RA response elements in gene promoters; (2) in non-genomic pathways it activates kinase-signaling cascades that converge with additional influences to regulate gene expression and mRNA translation. RA performs a critical role in morphogenesis of the developing embryo, which is reflected in spatio-temporally changing expression patterns of RA-synthesizing and RA-degrading enzymes and in its biophysical characteristics as a small diffusible lipid. Because its histological localization cannot be directly visualized for technical reasons, its sites of action in vivo are inferred from the locations of the metabolic enzymes and through use of two kinds of RA reporter systems. Here we explain techniques for use of RA reporter cells and RA reporter mice, and we describe in situ hybridization methods for the three major RA-degrading enzymes: CYP26A1, CYP26B1, and CYP26C1. Comparisons of the different indicators for sites of RA signaling demonstrate that local RA peaks and troughs are important for inferring some but not all locations of RA actions. When integrated within cells of living mice, expression of the RA reporter construct is rarely a simple measure of local RA levels, especially in the developing brain, but it appears to provide cues to an RA involvement in site-specific regulatory networks in combination with other spatial determinants.</p>

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</description>

<author>Yasuo Sakai et al.</author>


<category>Animals</category>

<category>Cell Line</category>

<category>Cytochrome P-450 Enzyme System</category>

<category>Female</category>

<category>Genes, Reporter</category>

<category>In Situ Hybridization</category>

<category>Male</category>

<category>Mice</category>

<category>RNA Probes</category>

<category>Tretinoin</category>

<category>beta-Galactosidase</category>

</item>




<item>
<title>Dietary Patterns and Body Mass Index in Children with Autism and Typically Developing Children</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/126</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/126</guid>
<pubDate>Fri, 08 Mar 2013 09:16:41 PST</pubDate>
<description>
	<![CDATA[
	<p>To determine whether dietary patterns (juice and sweetened non-dairy beverages, fruits, vegetables, fruits and vegetables, snack foods, and kid's meals) and associations between dietary patterns and body mass index (BMI) differed between 53 children with autism spectrum disorders (ASD) and 58 typically developing children, ages 3 to 11, multivariate regression models including interaction terms were used. Children with ASD were found to consume significantly more daily servings of sweetened beverages (2.6 versus 1.7, p=0.03) and snack foods (4.0 versus 3.0, p=0.01) and significantly fewer daily servings of fruits and vegetables (3.1 versus 4.4, p=0.006) than typically developing children. There was no evidence of statistical interaction between any of the dietary patterns and BMI z-score with autism status. Among all children, fruits and vegetables (p=0.004) and fruits alone (p=0.005) were positively associated with BMI z-score in our multivariate models. Children with ASD consume more energy-dense foods than typically developing children; however, in our sample, only fruits and vegetables were positively associated with BMI z-score.</p>

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</description>

<author>E. Whitney Evans et al.</author>


<category>Child Development Disorders, Pervasive</category>

<category>Body Mass Index</category>

<category>Food Habits</category>

</item>




<item>
<title>Evaluating merger and intersection of equivalence classes with one member in common</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/124</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/124</guid>
<pubDate>Fri, 08 Mar 2013 09:16:40 PST</pubDate>
<description>
	<![CDATA[
	<p>Sidman (1994) noted that the existence of a member that is common to more than one class may produce either class merger (union) or class intersection. A multiple-selection, matching-to-sample test was developed to examine the conditions under which these outcomes occur. Test trials each required three conditional discriminations involving selection or rejection of comparison stimuli under control of samples representing two categories. Test results obtained from an initial group of typical adults using familiar stimuli (DOG and BIRD, pictures of dogs and birds and relevant printed breed names (e.g., DALMATIAN, RETRIEVER) showed the conditional stimulus control best described as intersection. For example, the word DALMATIAN provided the context for selecting the dalmatian but not the retriever picture. However, these results may have depended on the participants' verbal history as English speakers. Would conditional-discrimination training with overlapping sets of laboratory-generated stimuli also result in intersection? Naive typical adults were assigned to one of three different training conditions. Like the participants tested with familiar stimuli, these participants demonstrated highly reliable test outcomes best described as showing class intersection, regardless of training condition. These findings begin to elucidate the necessary and sufficient conditions for establishing complex category-like classes of stimuli.</p>

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</description>

<author>Harry A. MacKay et al.</author>


<category>Adult</category>

<category>*Conditioning (Psychology)</category>

<category>Cues</category>

<category>*Discrimination Learning</category>

<category>Female</category>

<category>Humans</category>

<category>Male</category>

<category>Neuropsychological Tests</category>

<category>Photic Stimulation</category>

<category>*Verbal Learning</category>

<category>*Visual Perception</category>

<category>Young Adult</category>

</item>




<item>
<title>Environmental lead exposure and otoacoustic emissions in Andean children</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/125</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/125</guid>
<pubDate>Fri, 08 Mar 2013 09:16:40 PST</pubDate>
<description>
	<![CDATA[
	<p>Studies relating sensory hearing impairment to lead (Pb) exposure in children have presented inconsistent results. The objective of this study was to measure distortion product otoacoustic emissions (DPOAE), sounds emanating from the outer hair cells of the inner ear, in Pb-exposed children to determine the effects of Pb poisoning on the inner ear. DPOAE were recorded for 9 f(2) frequencies from 1187 to 7625 Hz on 102 ears of 53 Pb-exposed children (aged 6-16 yr) residing in Pb-contaminated environments in the Andes Mountains of Ecuador where Pb glazing of ceramics is the primary livelihood. Blood lead (PbB) levels ranged from 4.2 to 94.3 mug/dl (mean: 37.7; SD: 25.7; median: 36.4). The median PbB level was markedly higher than the Centers for Disease Control and Prevention (CDC) and World Health Organization (WHO) 10-mug/dl action level. Spearman rho correlation analyses of the relation between PbB level and DPOAE amplitude and between PbB level and DPOAE signal-to-noise ratio revealed no significant associations at any of the f(2) frequencies tested. In addition, no significant correlation (Spearman rho) between PbB level and hearing sensitivity for 6 pure-tone test frequencies from 1000 to 8000 Hz was found. Although the study group was found to have abnormally elevated PbB levels, in contrast to some earlier reports, the results of the current study showed no consistent Pb-induced sensory effects on the cochlea of Pb-intoxicated children.</p>

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</description>

<author>Leo H. Buchanan et al.</author>


<category>Adolescent</category>

<category>Auditory Threshold</category>

<category>Child</category>

<category>Cross-Sectional Studies</category>

<category>Ear, Inner</category>

<category>Ecuador</category>

<category>Environmental Exposure</category>

<category>Female</category>

<category>Hair Cells, Auditory, Outer</category>

<category>Hearing</category>

<category>Humans</category>

<category>Lead</category>

<category>Lead Poisoning, Nervous System,</category>

<category>Childhood</category>

<category>Male</category>

<category>Otoacoustic Emissions, Spontaneous</category>

<category>Otoscopy</category>

<category>Prevalence</category>

<category>Rural Health</category>

<category>Spectrophotometry, Atomic</category>

</item>




<item>
<title>Facilitating children&apos;s ability to distinguish symbols for emotions: the effects of background color cues and spatial arrangement of symbols on accuracy and speed of search</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/123</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/123</guid>
<pubDate>Fri, 08 Mar 2013 09:16:39 PST</pubDate>
<description>
	<![CDATA[
	<p>PURPOSE: Communication about feelings is a core element of human interaction. Aided augmentative and alternative communication systems must therefore include symbols representing these concepts. The symbols must be readily distinguishable in order for users to communicate effectively. However, emotions are represented within most systems by schematic faces in which subtle distinctions are difficult to represent. We examined whether background color cuing and spatial arrangement might help children identify symbols for different emotions.</p>
<p>METHOD: Thirty nondisabled children searched for symbols representing emotions within an 8-choice array. On some trials, a color cue signaled the valence of the emotion (positive vs. negative). Additionally, the symbols were either (a) organized with the negatively valenced symbols at the top and the positive symbols on the bottom of the display or (b) distributed randomly throughout. Dependent variables were accuracy and speed of responses.</p>
<p>RESULTS: The speed with which children could locate a target was significantly faster for displays in which symbols were clustered by valence, but only when the symbols had white backgrounds. Addition of a background color cue did not facilitate responses.</p>
<p>CONCLUSIONS: Rapid search was facilitated by a spatial organization cue, but not by the addition of background color. Further examination of the situations in which color cues may be useful is warranted.</p>

	]]>
</description>

<author>Krista M. Wilkinson et al.</author>


<category>Affective Symptoms</category>

<category>Child</category>

<category>Child Psychology</category>

<category>Child, Preschool</category>

<category>Color</category>

<category>Color Perception</category>

<category>*Communication</category>

<category>Communication Aids for Disabled</category>

<category>Cues</category>

<category>*Emotions</category>

<category>Facial Expression</category>

<category>Female</category>

<category>Humans</category>

<category>Male</category>

<category>Photic Stimulation</category>

<category>Reaction Time</category>

<category>Reference Values</category>

<category>Space Perception</category>

<category>*Symbolism</category>

</item>




<item>
<title>Food selectivity in children with autism spectrum disorders and typically developing children</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/122</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/122</guid>
<pubDate>Fri, 08 Mar 2013 09:16:38 PST</pubDate>
<description>
	<![CDATA[
	<p>OBJECTIVES: To define food selectivity and compare indices of food selectivity among children with autism spectrum disorders (ASDs) and typically developing children, and to assess the impact of food selectivity on nutrient adequacy.</p>
<p>STUDY DESIGN: Food selectivity was operationalized to include food refusal, limited food repertoire, and high-frequency single food intake using a modified food frequency questionnaire and a 3-day food record. Food selectivity was compared between 53 children with ASDs and 58 typically developing children age 3-11 years. Nutrient adequacy was assessed relative to the dietary reference intakes.</p>
<p>RESULTS: The children with ASDs exhibited more food refusal than typically developing children (41.7% of foods offered vs 18.9% of foods offered; P</p>
<p>CONCLUSIONS: Our findings suggest that food selectivity is more common in children with ASDs than in typically developing children, and that a limited food repertoire may be associated with nutrient inadequacies.</p>

	]]>
</description>

<author>Linda G. Bandini et al.</author>


<category>Case-Control Studies</category>

<category>Child</category>

<category>Child Development Disorders, Pervasive</category>

<category>Child Nutrition Sciences</category>

<category>Child, Preschool</category>

<category>Diet Surveys</category>

<category>Eating</category>

<category>Female</category>

<category>Food Habits</category>

<category>*Food Preferences</category>

<category>Humans</category>

<category>Male</category>

<category>Nutritional Status</category>

<category>Questionnaires</category>

</item>




<item>
<title>Gaze patterns during identity and emotion judgments in hearing adults and deaf users of American Sign Language</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/121</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/121</guid>
<pubDate>Fri, 08 Mar 2013 09:16:37 PST</pubDate>
<description>
	<![CDATA[
	<p>Deaf individuals rely on facial expressions for emotional, social, and linguistic cues. In order to test the hypothesis that specialized experience with faces can alter typically observed gaze patterns, twelve hearing adults and twelve deaf, early-users of American Sign Language judged the emotion and identity of expressive faces (including whole faces, and isolated top and bottom halves), while accuracy and fixations were recorded. Both groups recognized individuals more accurately from top than bottom halves, and emotional expressions from bottom than top halves. Hearing adults directed the majority of fixations to the top halves of faces in both tasks, but fixated the bottom half slightly more often when judging emotion than identity. In contrast, deaf adults often split fixations evenly between the top and bottom halves regardless of task demands. These results suggest that deaf adults have habitual fixation patterns that may maximize their ability to gather information from expressive faces.</p>

	]]>
</description>

<author>Susan M. Letourneau et al.</author>


<category>Adult</category>

<category>Attention</category>

<category>Cues</category>

<category>Deafness</category>

<category>*Emotions</category>

<category>*Facial Expression</category>

<category>Female</category>

<category>*Fixation, Ocular</category>

<category>Humans</category>

<category>*Judgment</category>

<category>Male</category>

<category>Middle Aged</category>

<category>*Orientation</category>

<category>*Pattern Recognition, Visual</category>

<category>Reference Values</category>

<category>*Sign Language</category>

<category>Young Adult</category>

</item>




<item>
<title>Non-Mendelian etiologic factors in neuropsychiatric illness: pleiotropy, epigenetics, and convergence</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/118</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/118</guid>
<pubDate>Fri, 08 Mar 2013 09:16:36 PST</pubDate>
<description>
	<![CDATA[
	<p>The target article by Charney on behavior genetics/genomics discusses how numerous molecular factors can inform heritability estimations and genetic association studies. These factors find application in the search for genes for behavioral phenotypes, including neuropsychiatric disorders. We elaborate upon how single causal factors can generate multiple phenotypes, and discuss how multiple causal factors may converge on common neurodevelopmental mechanisms.</p>

	]]>
</description>

<author>Curtis K. Deutsch et al.</author>


<category>Molecular Epidemiology</category>

<category>Neuropsychiatry</category>

</item>




<item>
<title>Meals in Our Household: reliability and initial validation of a questionnaire to assess child mealtime behaviors and family mealtime environments</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/120</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/120</guid>
<pubDate>Fri, 08 Mar 2013 09:16:36 PST</pubDate>
<description>
	<![CDATA[
	<p>Mealtimes in families with young children are increasingly of interest to nutrition and public health researchers, yet assessment tools are limited. Meals in Our Household is a new parent-report questionnaire that measures six domains: 1) structure of family meals, 2) problematic child mealtime behaviors, 3) use of food as reward, 4) parental concern about child diet, 5) spousal stress related to child's mealtime behavior, and 6) influence of child's food preferences on what other family members eat. Reliability and initial face, construct, and discriminant validity of the questionnaire were evaluated between January 2007 and December 2009 in two cross-sectional studies comprising a total of 305 parents of 3- to 11-year-old children (including 53 children with autism spectrum disorders). Internal consistencies (Cronbach's alpha) for the six domains averaged .77 across both studies. Test-retest reliability, assessed among a subsample of 44 parents who repeated the questionnaire after between 10 and 30 days, was excellent (Spearman correlations for the domain scores between two administrations ranged from 0.80 to 0.95). Initial construct validity of the instrument was supported by observation of hypothesized inter-relationships between domain scores that were of the same direction and similar magnitude in both studies. Consistent with discriminant validity, children with autism spectrum disorders had statistically significantly (P</p>

	]]>
</description>

<author>Sarah E. Anderson et al.</author>


<category>Child</category>

<category>Child Development Disorders, Pervasive</category>

<category>*Child Nutritional Physiological Phenomena</category>

<category>Child, Preschool</category>

<category>*Choice Behavior</category>

<category>Cross-Sectional Studies</category>

<category>*Family</category>

<category>Female</category>

<category>*Food Habits</category>

<category>*Food Preferences</category>

<category>Humans</category>

<category>Male</category>

<category>*Questionnaires</category>

<category>Social Environment</category>

<category>Socioeconomic Factors</category>

</item>




<item>
<title>Non-psychiatric health problems among psychiatric inpatients with intellectual disabilities</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/117</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/117</guid>
<pubDate>Fri, 08 Mar 2013 09:16:35 PST</pubDate>
<description>
	<![CDATA[
	<p>BACKGROUND: Physical distress resulting from medical problems has been found to cause increased behaviour problems in patients with intellectual disabilities (ID). Despite this fact, little has been documented on the medical problems of individuals with ID admitted for inpatient psychiatric care. We conducted an exploratory investigation based on a retrospective chart review of the medical problems and medications for 198 people with ID who had been admitted to a specialised inpatient psychiatric unit. Most patients were referred for admission because of aggressive, disruptive and self-injurious behaviours. The average length of stay was 17.6 days.</p>
<p>METHODS: We tallied the total number of medical problems and medications listed in the patients' discharge summaries. Because longer stays are disruptive, costly and associated with greater overall impairment, we examined the relationship between length of stay and frequency of discharge medical diagnoses. We also assessed whether or not the number of psychoactive medications correlated with the number of medical diagnoses. The effects of other demographic and diagnostic variables on rates of medical diagnoses and medications were also evaluated, including gender, age group (16-25, 26-45, 46-60, >60), level of ID (mild, moderate or severe ID) and diagnosis of an autism spectrum disorder or Down syndrome (DS).</p>
<p>RESULTS: Inpatients with a higher number of medical diagnoses had longer lengths of stay (Spearman r = +0.32, P < 0.0001). There was a significant correlation between number of psychoactive medications and number of medical problems (Spearman r = +0.32, P < 0.0001). The most frequent medical comorbidity was constipation, reported in 60% of the inpatients (n = 118), while gastro-esophageal reflux disease was identified in 38% (n = 75). Older inpatients had an increased number of medical problems, as might be expected, but a diagnosis of an autism spectrum disorder, gender and level of ID had no detectible effect on rates of either medical diagnoses or medications. There were only 13 inpatients with DS; in this modest sample, it was found that they had higher rates of osteoarthritis, cardiac problems, hearing loss, hypothyroidism and sleep apnoea than peers without DS, as is consistent with previous findings on overrepresented conditions in this trisomy.</p>
<p>CONCLUSIONS: In the present study, individuals with ID admitted for inpatient psychiatric care exhibited high rates of medical problems, and these were associated with duration of inpatient stay. Based on these findings, further investigation of the effects of medical problems on behaviour among individuals with ID admitted for inpatient psychiatric care is warranted.</p>

	]]>
</description>

<author>Lauren Charlot et al.</author>


<category>Adolescent</category>

<category>Adult</category>

<category>Aged</category>

<category>Cohort Studies</category>

<category>Constipation</category>

<category>Female</category>

<category>Gastroesophageal Reflux</category>

<category>*Health Status</category>

<category>Hospitals, Psychiatric</category>

<category>Humans</category>

<category>Intellectual Disability</category>

<category>Length of Stay</category>

<category>Longitudinal Studies</category>

<category>Male</category>

<category>Mentally Disabled Persons</category>

<category>Middle Aged</category>

<category>Needs Assessment</category>

<category>Pilot Projects</category>

<category>Residential Facilities</category>

<category>Young Adult</category>

</item>




<item>
<title>Preliminary investigation of visual attention to human figures in photographs: potential considerations for the design of aided AAC visual scene displays</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/116</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/116</guid>
<pubDate>Fri, 08 Mar 2013 09:16:34 PST</pubDate>
<description>
	<![CDATA[
	<p>PURPOSE: Many individuals with complex communication needs may benefit from visual aided augmentative and alternative communication systems. In visual scene displays (VSDs), language concepts are embedded into a photograph of a naturalistic event. Humans play a central role in communication development and might be important elements in VSDs. However, many VSDs omit human figures. In this study, the authors sought to describe the distribution of visual attention to humans in naturalistic scenes as compared with other elements.</p>
<p>METHOD: Nineteen college students observed 8 photographs in which a human figure appeared near 1 or more items that might be expected to compete for visual attention (such as a Christmas tree or a table loaded with food). Eye-tracking technology allowed precise recording of participants' gaze. The fixation duration over a 7-s viewing period and latency to view elements in the photograph were measured.</p>
<p>RESULTS: Participants fixated on the human figures more rapidly and for longer than expected based on the size of these figures, regardless of the other elements in the scene.</p>
<p>CONCLUSIONS: Human figures attract attention in a photograph even when presented alongside other attractive distracters. Results suggest that humans may be a powerful means to attract visual attention to key elements in VSDs.</p>

	]]>
</description>

<author>Krista M. Wilkinson et al.</author>


<category>Adolescent</category>

<category>Attention</category>

<category>Cellular Phone</category>

<category>*Communication Aids for Disabled</category>

<category>Communication Disorders</category>

<category>*Equipment Design</category>

<category>Eye Movements</category>

<category>Female</category>

<category>Form Perception</category>

<category>Humans</category>

<category>Male</category>

<category>*Photography</category>

<category>Pilot Projects</category>

<category>Reaction Time</category>

<category>Young Adult</category>

</item>




<item>
<title>Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/115</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/115</guid>
<pubDate>Fri, 08 Mar 2013 09:16:33 PST</pubDate>
<description>
	<![CDATA[
	<p>The ganglionic eminence contributes cells to several forebrain structures including the cerebral cortex, for which it provides GABAergic interneurons. Migration of neuronal precursors from the retinoic-acid rich embryonic ganglionic eminence to the cerebral cortex is known to be regulated by several factors, but retinoic acid has not been previously implicated. We found retinoic acid to potently inhibit cell migration in slice preparations of embryonic mouse forebrains, which was reversed by an antagonist of the dopamine-D(2) receptor, whose gene is transcriptionally regulated by retinoic acid. Histone-deacetylase inhibitors, which amplify nuclear receptor-mediated transcription, potentiated the inhibitory effect of retinoic acid. Surprisingly, when retinoic acid signalling was completely blocked with a pan-retinoic acid receptor antagonist, this also decreased cell migration into the cortex, implying that a minimal level of endogenous retinoic acid is necessary for tangential migration. Given these opposing effects of retinoic acid in vitro, the in vivo contribution of retinoic acid to migration was tested by counting GABAergic interneurons in cortices of adult mice with experimental reductions in retinoic acid signalling: a range of perturbations resulted in significant reductions in the numerical density of some GABAergic interneuron subpopulations. These observations suggest functions of retinoic acid in interneuron diversity and organization of cortical excitatory-inhibitory balance. for Neurochemistry.</p>

	]]>
</description>

<author>James E. Crandall et al.</author>


<category>Amino Acids</category>

<category>Animals</category>

<category>Animals, Newborn</category>

<category>Calcium-Binding Protein, Vitamin D-Dependent</category>

<category>Cell Movement</category>

<category>Cerebral Cortex</category>

<category>Dopamine Antagonists</category>

<category>Dose-Response Relationship, Drug</category>

<category>Embryo, Mammalian</category>

<category>Enzyme Inhibitors</category>

<category>Enzyme-Linked Immunosorbent Assay</category>

<category>Female</category>

<category>Food, Formulated</category>

<category>Gene Expression Regulation, Developmental</category>

<category>Hydroxamic Acids</category>

<category>Isoenzymes</category>

<category>Mice</category>

<category>Mice, Inbred C57BL</category>

<category>Mice, Knockout</category>

<category>Neurons</category>

<category>Organ Culture Techniques</category>

<category>Parvalbumins</category>

<category>Pregnancy</category>

<category>Retinal Dehydrogenase</category>

<category>Retinol-Binding Proteins</category>

<category>Salicylamides</category>

<category>Signal Transduction</category>

<category>Telencephalon</category>

<category>Tretinoin</category>

<category>Valproic Acid</category>

<category>Vitamin A</category>

<category>gamma-Aminobutyric Acid</category>

</item>




<item>
<title>Stimulus equivalence, generalization, and contextual stimulus control in verbal classes</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/113</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/113</guid>
<pubDate>Fri, 08 Mar 2013 09:16:32 PST</pubDate>
<description>
	<![CDATA[
	<p>Stimulus generalization and contextual control affect the development of equivalence classes. Experiment 1 demonstrated primary stimulus generalization from the members of trained equivalence classes. Adults were taught to match six spoken Icelandic nouns and corresponding printed words and pictures to one another in computerized three-choice matching-to-sample tasks. Tests confirmed that six equivalence classes had formed. Without further training, plural forms of the stimuli were presented in tests for all matching performances. All participants demonstrated virtually errorless performances. In Experiment 2, classifications of the nouns used in Experiment 1 were brought under contextual control. Three nouns were feminine and three were masculine. The match-to-sample training taught participants to select a comparison of the same number as the sample (i.e., singular or plural) in the presence of contextual stimulus A regardless of noun gender. Concurrently, in the presence of contextual stimulus B, participants were taught to select a comparison of the same gender as the sample (i.e., feminine or masculine), regardless of number. Generalization was assessed using a card-sorting test. All participants eventually sorted the cards correctly into gender and number stimulus classes. When printed words used in training were replaced by their picture equivalents, participants demonstrated almost errorless performances.</p>

	]]>
</description>

<author>Zuilma Gabriela Sigurethardottir et al.</author>


<category>Generalization (Psychology)</category>

<category>Generalization, Stimulus</category>

<category>Verbal Behavior</category>

</item>




<item>
<title>Stimulant use under a prison treatment protocol for attention-deficit/hyperactivity disorder</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/114</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/114</guid>
<pubDate>Fri, 08 Mar 2013 09:16:32 PST</pubDate>
<description>
	<![CDATA[
	<p>Although stimulant medications are the mainstay of effective intervention for attention-deficit/ hyperactivity disorder (ADHD), their use presents a daunting scenario for psychiatry, nursing, and custody staff in correctional settings, where reported prevalence rates range from 9% to 45%. The reported rates, however, may overestimate actual prevalence in general and need for treatment in particular. Under a monitored protocol that required documentation of history, diagnosis, lack of response to nonstimulant treatment, and significant functional impairment, less than 1% of male inmates in the Massachusetts state prison system met criteria for treatment with stimulants. Although this protocol did not attempt to determine overall ADHD prevalence rates, the relatively low number of inmates with compelling reasons for stimulant treatment may provide a more realistic idea of the likely consequences of allowing access to this intervention.</p>

	]]>
</description>

<author>Kenneth L. Appelbaum</author>


<category>Attention Deficit Disorder with Hyperactivity</category>

<category>therapy</category>

<category>Central Nervous System Stimulants</category>

<category>Humans</category>

<category>Male</category>

<category>Prevalence</category>

<category>Prisons</category>

</item>




<item>
<title>TerraKids: An Interactive Web Site Where Kids Learn about Saving the Environment</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/112</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/112</guid>
<pubDate>Fri, 08 Mar 2013 09:16:31 PST</pubDate>
<description>
	<![CDATA[
	<p>“TerraKids” is the name of a Web site that is, for the present, purely fictional. It is a safe, secure site where 8- to 12-year-old kids become catalysts for a greener Earth by learning about the environment and the role they and their families can play in reducing global warming.  Today, TerraKids exists only in thought and in this essay, but it could be live on the Web in the very near future. By making use of what we know about a science of behavior change, we can build a Web site that can help move millions of people to a greener world.</p>

	]]>
</description>

<author>Janet S. Twyman</author>


<category>Conservation of Natural Resources</category>

<category>Child</category>

<category>Internet</category>

</item>




<item>
<title>The double ABCX model of adaptation in racially diverse families with a school-age child with autism</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/111</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/111</guid>
<pubDate>Fri, 08 Mar 2013 09:16:30 PST</pubDate>
<description>
	<![CDATA[
	<p>In this study, the Double ABCX model of family adaptation was used to explore the impact of severity of autism symptoms, behavior problems, social support, religious coping, and reframing, on outcomes related to family functioning and parental distress. The sample included self-report measures collected from 195 families raising school-age children with autism from racially diverse backgrounds throughout the United States.</p>
<p>Hierarchical regression results revealed that the Double ABCX model of family adaptation accounted for a substantial amount of the variance in family functioning (28%) and parental distress (46%).</p>
<p>Findings suggest that child behavior problems and reframing are most strongly associated with family outcomes. Clinical implications for working with these families, including the use of strength-based approaches, are discussed.</p>

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</description>

<author>Margaret M. Manning et al.</author>


<category>*Adaptation, Psychological</category>

<category>Autistic Disorder</category>

<category>Child</category>

<category>Child Behavior</category>

<category>Cultural Diversity</category>

<category>Family</category>

<category>Female</category>

<category>Humans</category>

<category>Male</category>

<category>Models, Psychological</category>

<category>Parenting</category>

<category>Questionnaires</category>

<category>Regression Analysis</category>

<category>Social Support</category>

<category>Stress, Psychological</category>

</item>




<item>
<title>The effect of a telephone-based health coaching disease management program on Medicaid members with chronic conditions</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/110</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/110</guid>
<pubDate>Fri, 08 Mar 2013 09:16:29 PST</pubDate>
<description>
	<![CDATA[
	<p>BACKGROUND: Despite the growing popularity of disease management programs for chronic conditions, evidence regarding the effect of these programs has been mixed. In addition, few peer-reviewed studies have examined the effect of these programs on publicly insured populations.</p>
<p>OBJECTIVES: To examine the effect of a telephone-based health coaching disease management program on healthcare utilization and expenditures in Medicaid members with chronic conditions.</p>
<p>RESEARCH DESIGN: Using a difference-in-differences analysis, we examined changes in hospitalizations, emergency department (ED) visits, ambulatory care visits, and Medicaid expenditures among program members for 1 year before and 2 years after their enrollment compared with a matched comparison group.</p>
<p>SUBJECTS: Medicaid members aged 18 to 64 with a diagnosis of qualifying chronic conditions and 2 acute health service events of hospitalizations and/or ED visits within a 12-month period.</p>
<p>RESULTS: Changes in acute hospitalizations, ambulatory care visits, and Medicaid expenditures before and after program enrollment were similar between the 2 study groups. However, during the second year after enrollment, program members had a significantly smaller decrease in ED visits than the comparisons (8% in program members and 23% in comparisons, P value=0.03).</p>
<p>CONCLUSIONS: Compared with a matched comparison group, the telephone-based health coaching disease management program did not demonstrate significant effects on healthcare utilization and expenditures in Medicaid members with chronic conditions.</p>

	]]>
</description>

<author>Wen-Chieh Lin et al.</author>


<category>Adolescent</category>

<category>Adult</category>

<category>Chronic Disease</category>

<category>*Disease Management</category>

<category>Emergency Service, Hospital</category>

<category>Female</category>

<category>Health Expenditures</category>

<category>Health Services</category>

<category>Hospitalization</category>

<category>Humans</category>

<category>Male</category>

<category>Medicaid</category>

<category>Middle Aged</category>

<category>*Telephone</category>

<category>United States</category>

<category>Young Adult</category>

</item>




<item>
<title>Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/108</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/108</guid>
<pubDate>Fri, 08 Mar 2013 09:16:28 PST</pubDate>
<description>
	<![CDATA[
	<p>Vertebrate hearing and balance are based in complex asymmetries of inner ear structure. Here, we identify retinoic acid (RA) as an extrinsic signal that acts directly on the ear rudiment to affect its compartmentalization along the anterior-posterior axis. A rostrocaudal wave of RA activity, generated by tissues surrounding the nascent ear, induces distinct responses from anterior and posterior halves of the inner ear rudiment. Prolonged response to RA by posterior otic tissue correlates with Tbx1 transcription and formation of mostly nonsensory inner ear structures. By contrast, anterior otic tissue displays only a brief response to RA and forms neuronal elements and most sensory structures of the inner ear.</p>

	]]>
</description>

<author>Jinwoong Bok et al.</author>


<category>Animals</category>

<category>Body Patterning</category>

<category>Chick Embryo</category>

<category>Cycloheximide</category>

<category>Ear, Inner</category>

<category>Gene Expression Regulation, Developmental</category>

<category>In Situ Hybridization</category>

<category>Mice</category>

<category>Microspheres</category>

<category>Signal Transduction</category>

<category>T-Box Domain Proteins</category>

<category>Tretinoin</category>

<category>beta-Galactosidase</category>

</item>




<item>
<title>The influence of a sensitive period for auditory-visual integration in children with cochlear implants</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/109</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/109</guid>
<pubDate>Fri, 08 Mar 2013 09:16:28 PST</pubDate>
<description>
	<![CDATA[
	<p>PURPOSE: Children who experience long periods of auditory deprivation are susceptible to large-scale reorganization of auditory cortical areas responsible for the perception of speech and language. One consequence of this reorganization is that integration of combined auditory and visual information may be altered after hearing is restored with a cochlear implant. Our goal was to investigate the effects of reorganization in a task that examines performance during multisensory integration.</p>
<p>METHODS: Reaction times to the detection of basic auditory (A), visual (V), and combined auditory-visual (AV) stimuli were examined in a group of normally hearing children, and in two groups of cochlear implanted children: (1) early implanted children in whom cortical auditory evoked potentials (CAEPs) fell within normal developmental limits, and (2) late implanted children in whom CAEPs were outside of normal developmental limits. Miller's test of the race model inequality was performed for each group in order to examine the effects of auditory deprivation on multisensory integration abilities after implantation.</p>
<p>RESULTS: Results revealed a significant violation of the race model inequality in the normally hearing and early implanted children, but not in the group of late implanted children.</p>
<p>CONCLUSION: These results suggest that coactivation to multi-modal sensory input cannot explain the decreased reaction times to multi-modal input in late implanted children. These results are discussed in regards to current models for coactivation to redundant sensory information.</p>

	]]>
</description>

<author>Phillip M. Gilley et al.</author>


<category>Acoustic Stimulation</category>

<category>Adolescent</category>

<category>Adult</category>

<category>Age Factors</category>

<category>Analysis of Variance</category>

<category>Auditory Perception</category>

<category>Child</category>

<category>Child Development</category>

<category>*Cochlear Implants</category>

<category>Deafness</category>

<category>Female</category>

<category>Humans</category>

<category>Male</category>

<category>Photic Stimulation</category>

<category>Probability</category>

<category>Reaction Time</category>

<category>Visual Perception</category>

<category>Young Adult</category>

</item>




<item>
<title>Promoting and Regulating Safe Medication Administration in Nursing Homes</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/107</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/107</guid>
<pubDate>Thu, 07 Mar 2013 08:59:39 PST</pubDate>
<description>
	<![CDATA[
	<p>Nurses' fear of blame following a medication event and confusion about the error-reporting requirements of multiple regulatory bodies that oversee nursing practice and nursing home operations can stifle the discussion and analysis of medication administration events to promote patient safety. The Massachusetts Board of Registration in Nursing and the University of Massachusetts Medical School Center for Health Policy and Research convened the Massachusetts Medication Safety Alliance, a 15-member collaborative of regulatory agencies and long-term care providers, to develop the Nurse-Employer Medication Safety Partnership Model to cultivate a safety culture in Massachusetts nursing homes that supports voluntary medication-event recognition and disclosure by nurses. A proactive approach to the Board's public protection mission, the model will promote public safety through early intervention and quality improvement. To guide the model's development, the Alliance assessed the perceptions of 1,286 nurses working in 109 Massachusetts nursing homes, finding more than half rated their practice environment as punitive and identified fears of blame, disciplinary action, and lawsuits as barriers to medication-event reporting.</p>

	]]>
</description>

<author>Teresa Anderson et al.</author>


<category>Nursing Homes</category>

<category>Nursing Staff</category>

<category>Medication Errors</category>

<category>Geriatric Nursing</category>

<category>Safety Management</category>

</item>




<item>
<title>Is there a psychiatrist in the house? Integrating child psychiatry into the pediatric medical home</title>
<link>http://escholarship.umassmed.edu/healthpolicy_pp/106</link>
<guid isPermaLink="true">http://escholarship.umassmed.edu/healthpolicy_pp/106</guid>
<pubDate>Thu, 07 Mar 2013 08:30:55 PST</pubDate>
<description>
	<![CDATA[
	<p>To address the mental health needs of children and adolescents, Patient-Centered Medical Homes (PCMHs) need the capacity to screen for and detect significant mental health symptoms at the earliest stages of expression, the ability to develop treatment plans with patients and families, and systems to monitor and guide treatment over time. Given the complex nature of children’s mental health issues, primary care providers cannot be expected to perform these functions without the help of specialized child psychiatry resources offered in a collaborative fashion. PCMHs need access to consultation services and specialized care coordination.</p>

	]]>
</description>

<author>David M. Keller et al.</author>


<category>Patient-Centered Care</category>

<category>Primary Health Care</category>

<category>Mental Health Services</category>

<category>Child Psychiatry</category>

<category>Child Health Services</category>

</item>





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