Center for Health Policy and Research (CHPR) Publications

Title

Prescribing patterns for patients with posttraumatic stress disorder

UMMS Affiliation

Department of Family Medicine and Community Health; Center for Health Policy and Research; Clinical and Population Health Research

Date

12-4-2003

Document Type

Article

Medical Subject Headings

Adult; Community Mental Health Centers; Drug Prescriptions; Female; Health Services Research; Humans; Male; Middle Aged; Serotonin Uptake Inhibitors; Stress Disorders, Post-Traumatic; United States

Disciplines

Health Services Administration | Health Services Research | Public Health

Abstract

OBJECTIVE: The little information available about prescribing patterns for persons with posttraumatic stress disorder comes from male combat-veteran populations treated through programs of the Department of Veterans Affairs. The objective of this study was to comprehensively evaluate prescribing patterns for persons with a diagnosis of posttraumatic stress disorder (PTSD) in a community-based nonveteran sample in which women were well represented.

METHODS: Prescription claims paid in December 1999 for New Hampshire Medicaid recipients with diagnostic codes for PTSD were analyzed. Frequencies of prescriptions for categories of medication were compared between patients with PTSD (N=165) and patients with major depression alone (N=2,208) and those with major depression co-occurring with PTSD (N=171).

RESULTS: The patients with PTSD were predominantly women who were receiving services at community mental health centers. Selective serotonin reuptake inhibitors were more frequently prescribed for major depression (32 percent of cases) than for PTSD (23 percent). Other novel antidepressants were more frequently prescribed for major depression co-occurring with PTSD (25 percent of cases) than for major depression alone (18 percent). Atypical antipsychotic medications were more frequently prescribed for PTSD (17 percent of cases) and for major depression co-occurring with PTSD (20 percent) than for major depression alone (9 percent). Benzodiazepines and related hypnotics, trazodone, and mood stabilizers were more frequently prescribed for major depression co-occurring with PTSD than for major depression alone.

CONCLUSIONS: The findings suggest that many outpatients who have PTSD are treated aggressively with medication, particularly when PTSD co-occurs with major depression, and that there are discrepancies between actual prescribing patterns and prescribing guidelines. These findings overlap trends observed in veteran populations.

Rights and Permissions

Citation: Psychiatr Serv. 2003 Dec;54(12):1618-21.

Related Resources

Link to Article in PubMed