Adjusting and censoring electronic monitoring device data. Implications for study outcomes
Graduate School of Nursing; Center for Infectious Disease and Vaccine Research
Anti-HIV Agents; Data Collection; Drug Monitoring; Drug Packaging; HIV Infections; Humans; Medical Records; Patient Compliance; Research
Nursing | Public Health and Community Nursing
Electronic monitoring device (EMD) data are widely used to measure adherence in HIV medication adherence research. EMD data represent an objective measure of adherence and arguably provide more valid data than other methods such as self-reported measures, pill counts, and drug level concentration. Moreover, EMD data are longitudinal, include many measurements, and yield a rich data set. This article illustrates potential pitfalls associated with this measurement technique, including lack of clarity associated with EMD data, and the extent to which adherence outcomes are affected by data management decisions. Recommendations are given regarding what information should be included in publications that report results based on EMD data so as to facilitate comparisons between studies.
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Citation: J Acquir Immune Defic Syndr. 2006 Dec 1;43 Suppl 1:S88-95. Link to article on publisher's site