GSBS Student Publications

Title

mRNA and cytoskeletal filaments

GSBS Program

Biochemistry & Molecular Pharmacology

UMMS Affiliation

Graduate School of Biomedical Sciences

Date

2-1-1997

Document Type

Article

Medical Subject Headings

Biological Transport; Cytoskeleton; Microfilaments; RNA, Messenger

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

The localization of some mRNAs to distinct intracellular regions is achieved through interactions of the mRNA with cytoskeletal filaments. RNA-cytoskeletal interactions exist that influence the transport, anchoring and translation of mRNA. Recent analysis of RNA movements in living cells suggests the formation of RNA granules and their active transport along microtubules. The anchoring and translation of mRNA may be mediated by interactions with orthogonal networks of F-actin and elongation factor 1alpha.

Rights and Permissions

Citation: Curr Opin Cell Biol. 1997 Feb;9(1):109-15.

Related Resources

Link to article in PubMed

Journal Title

Current opinion in cell biology

PubMed ID

9013679