Calculating the potential of C2 domains for membrane binding
Graduate School of Biomedical Sciences; Program in Molecular Medicine
Medical Subject Headings
Binding Sites; Calcium; *Calcium-Binding Proteins; Cell Membrane; Electrostatics; Membrane Glycoproteins; Models, Molecular; Nerve Tissue Proteins; Protein Binding; Protein Kinase C; *Protein Structure, Tertiary; Synaptotagmins
Life Sciences | Medicine and Health Sciences
A recent report in Molecular Cell demonstrates the ability of electrostatic calculations to predict the membrane binding properties of structurally characterized C2 domains and assign probable membrane targeting functions to numerous uncharacterized C2 domains.
Rights and Permissions
Citation: Dev Cell. 2002 Feb;2(2):132-3.
Merithew, Eric Lee and Lambright, David G., "Calculating the potential of C2 domains for membrane binding" (2002). GSBS Student Publications. 858.