GSBS Student Publications

Title

Calculating the potential of C2 domains for membrane binding

UMMS Affiliation

Graduate School of Biomedical Sciences; Program in Molecular Medicine

Date

2-8-2002

Document Type

Article

Medical Subject Headings

Binding Sites; Calcium; *Calcium-Binding Proteins; Cell Membrane; Electrostatics; Membrane Glycoproteins; Models, Molecular; Nerve Tissue Proteins; Protein Binding; Protein Kinase C; *Protein Structure, Tertiary; Synaptotagmins

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

A recent report in Molecular Cell demonstrates the ability of electrostatic calculations to predict the membrane binding properties of structurally characterized C2 domains and assign probable membrane targeting functions to numerous uncharacterized C2 domains.

Rights and Permissions

Citation: Dev Cell. 2002 Feb;2(2):132-3.

Related Resources

Link to article in PubMed

Journal Title

Developmental cell

PubMed ID

11832238