GSBS Student Publications


Transcriptional control: repression by local chromatin modification

GSBS Program

Biochemistry & Molecular Pharmacology

UMMS Affiliation

Graduate School of Biomedical Sciences; Program in Molecular Medicine



Document Type


Medical Subject Headings

Alcohol Oxidoreductases; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle; Chromatin; *Chromosomal Proteins, Non-Histone; CpG Islands; DNA Methylation; DNA-Binding Proteins; Drosophila melanogaster; Gene Expression Regulation; *Histone Deacetylases; Humans; Methyl-CpG-Binding Protein 2; Models, Genetic; Phosphoproteins; Proteins; Repressor Proteins; *Saccharomyces cerevisiae Proteins; Transcription Factors; Transcription, Genetic; Zinc Fingers


Life Sciences | Medicine and Health Sciences


It is becoming increasingly clear that chromatin modification plays a fundamental part in transcriptional control. Recent studies provide new insights into how transcriptional repressors, in addition to blocking activators, may recruit repression complexes that include chromatin modification factors.

Rights and Permissions

Citation: Curr Biol. 1998 Sep 24;8(19):R683-6.

Related Resources

Link to article in PubMed

Journal Title

Current biology : CB

PubMed ID