GSBS Student Publications

Title

Herbal medicines for the management of opioid addiction: safe and effective alternatives to conventional pharmacotherapy

Student Author(s)

Jeanine Ward

GSBS Program

MS in Clinical Investigation

UMMS Affiliation

Department of Emergency Medicine, Division of Medical Toxicology

Date

12-1-2011

Document Type

Article

Medical Subject Headings

Analgesics, Opioid; Animals; Behavior, Addictive; Drugs, Chinese Herbal; use; Humans; Plant Preparations; use; Substance-Related Disorders

Disciplines

Emergency Medicine | Medical Toxicology | Pharmacy and Pharmaceutical Sciences

Abstract

Striking increases in the abuse of opioids have expanded the need for pharmacotherapeutic interventions. The obstacles that confront effective treatment of opioid addiction - shortage of treatment professionals, stigma associated with treatment and the ability to maintain abstinence - have led to increased interest in alternative treatment strategies among both treatment providers and patients alike. Herbal products for opioid addiction and withdrawal, such as kratom and specific Chinese herbal medications such as WeiniCom, can complement existing treatments. Unfortunately, herbal treatments, while offering some advantages over existing evidence-based pharmacotherapies, have poorly described pharmacokinetics, a lack of supportive data derived from well controlled clinical trials, and severe toxicity, the cause for which remains poorly defined. Herbal products, therefore, require greater additional testing in rigorous clinical trials before they can expect widespread acceptance in the management of opioid addiction.

Rights and Permissions

Citation: CNS Drugs. 2011 Dec 1;25(12):999-1007. doi: 10.2165/11596830-000000000-00000. Link to article on publisher's site

DOI of Published Version

10.2165/11596830-000000000-00000

Related Resources

Link to Article in PubMed

Journal Title

CNS drugs

PubMed ID

22133323