GSBS Student Publications

Title

Prevalence and clinical characteristics of right ventricular dysfunction in transient stress cardiomyopathy

Student Author(s)

Timothy Fitzgibbons

GSBS Program

Interdisciplinary Graduate Program

UMMS Affiliation

Department of Cardiology; Department of Medicine, Division of Cardiovascular Medicine

Date

5-4-2009

Document Type

Article

Medical Subject Headings

Aged; Cardiomyopathies; Cohort Studies; Coronary Angiography; Female; Humans; Male; Massachusetts; Middle Aged; Prevalence; Prognosis; Retrospective Studies; Stress, Physiological; Stress, Psychological; Time Factors; Ventricular Dysfunction, Right

Disciplines

Cardiology | Cardiovascular Diseases

Abstract

Transient stress cardiomyopathy (TSC) is a cause of reversible left ventricular (LV) dysfunction that is increasingly recognized. Reports to date have focused primarily on LV involvement, with little attention paid to associated right ventricular (RV) dysfunction. With other forms of LV dysfunction, RV involvement has been shown to confer an adverse prognosis. Prevalence, clinical characteristics, and short-term prognosis of RV dysfunction in TSC remain ill-defined. Presenting echocardiograms of 40 patients with TSC were reviewed. RV function was assessed by evaluating regional wall motion and calculating a wall motion score index (WMSI). RV dysfunction was defined as a WMSI >1.0. Clinical and demographic characteristics of patients with and without RV dysfunction were compared. RV dysfunction was identified in 27% of patients (11 of 40). RV WMSI was 1.20 +/- 0.30 for the entire cohort compared with 1.72 +/- 0.30 for those with RV dysfunction (p 1/4 of cases of TSC. Although associated with higher B-type natriuretic peptide levels, higher pulmonary artery systolic pressures, and longer hospital stays, RV dysfunction was not associated with significant differences in short-term cardiac morbidity or increased early mortality.

Rights and Permissions

Citation: 2009 May 4. Link to article on publisher's site

DOI of Published Version

10.1016/j.amjcard.2009.02.049

Related Resources

Link to Article in PubMed

Journal Title

The American journal of cardiology

PubMed ID

19576334