Title

MicroRNA therapeutics

Student Author(s)

Jennifer Broderick

GSBS Program

Neuroscience

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology

Date

12-1-2011

Document Type

Article

Medical Subject Headings

MicroRNAs

Disciplines

Life Sciences | Medicine and Health Sciences | Neuroscience and Neurobiology

Abstract

MicroRNAs (miRNAs) provide new therapeutic targets for many diseases, while their myriad roles in development and cellular processes make them fascinating to study. We still do not fully understand the molecular mechanisms by which miRNAs regulate gene expression nor do we know the complete repertoire of mRNAs each miRNA regulates. However, recent progress in the development of effective strategies to block miRNAs suggests that anti-miRNA drugs may soon be used in the clinic.

Rights and Permissions

Citation: Gene Ther. 2011 Dec;18(12):1104-10. doi: 10.1038/gt.2011.50. Epub 2011 Apr 28. Link to article on publisher's site

Related Resources

Link to Article in PubMed