Title
MicroRNA therapeutics
GSBS Program
Neuroscience
UMMS Affiliation
Department of Biochemistry and Molecular Pharmacology
Date
12-1-2011
Document Type
Article
Medical Subject Headings
MicroRNAs
Disciplines
Life Sciences | Medicine and Health Sciences | Neuroscience and Neurobiology
Abstract
MicroRNAs (miRNAs) provide new therapeutic targets for many diseases, while their myriad roles in development and cellular processes make them fascinating to study. We still do not fully understand the molecular mechanisms by which miRNAs regulate gene expression nor do we know the complete repertoire of mRNAs each miRNA regulates. However, recent progress in the development of effective strategies to block miRNAs suggests that anti-miRNA drugs may soon be used in the clinic.
Rights and Permissions
Citation: Gene Ther. 2011 Dec;18(12):1104-10. doi: 10.1038/gt.2011.50. Epub 2011 Apr 28. Link to article on publisher's site