GSBS Student Publications

Title

Menage a Trio during BMP-Mediated Retrograde Signaling at the NMJ

Student Author(s)

Yuly F. Fuentes Medel

GSBS Program

Neuroscience

UMMS Affiliation

Department of Neurobiology; Budnik Lab; Graduate School of Biomedical Sciences, Neuroscience Program

Date

5-27-2010

Document Type

Article

Medical Subject Headings

Bone Morphogenetic Proteins; Neuromuscular Junction; Drosophila Proteins; Guanine Nucleotide Exchange Factors; Motor Neurons; Phosphoproteins; Protein-Serine-Threonine Kinases; Synapses

Disciplines

Neuroscience and Neurobiology

Abstract

In flies, retrograde BMP signaling is an important mechanism by which postsynaptic cells regulate the structure and function of presynaptic terminals, ostensibly through changes in gene expression. Transcriptional targets, however, have remained mysterious. In this issue of Neuron, Haghighi and colleagues begin to unravel this puzzle by identifying the cytoskeletal regulator Trio.

Rights and Permissions

Citation: Neuron. 2010 May 27;66(4):473-5. Link to article on publisher's site

DOI of Published Version

10.1016/j.neuron.2010.05.016

Related Resources

Link to Article in PubMed

Journal Title

Neuron

PubMed ID

20510851