GSBS Student Publications

Title

Intravascular lymphoma masquerading as Vogt-Koyanagi-Harada syndrome

UMMS Affiliation

Graduate School of Biomedical Sciences; Department of Ophthalmology

Date

6-24-2008

Document Type

Article

Medical Subject Headings

Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Blood Vessels; Cyclophosphamide; Diagnosis, Differential; Doxorubicin; Fluorescein Angiography; Humans; L-Lactate Dehydrogenase; Lymphoma; Male; Middle Aged; Prednisolone; Skin; Treatment Outcome; Uveomeningoencephalitic Syndrome; Vascular Neoplasms; Vincristine; Vision Disorders

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

PURPOSE: To describe the clinical course of a case of intravascular lymphoma. DESIGN: Case report.

METHODS: Retrospective chart review.

RESULTS: A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints.

CONCLUSIONS: Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.

Rights and Permissions

Citation: Ocul Immunol Inflamm. 2008 May-Jun;16(3):123-6. Link to article on publisher's site

DOI of Published Version

10.1080/09273940802023810

Related Resources

Link to Article in PubMed

Journal Title

Ocular immunology and inflammation

PubMed ID

18569804