Intravascular lymphoma masquerading as Vogt-Koyanagi-Harada syndrome
Graduate School of Biomedical Sciences; Department of Ophthalmology
Medical Subject Headings
Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Blood Vessels; Cyclophosphamide; Diagnosis, Differential; Doxorubicin; Fluorescein Angiography; Humans; L-Lactate Dehydrogenase; Lymphoma; Male; Middle Aged; Prednisolone; Skin; Treatment Outcome; Uveomeningoencephalitic Syndrome; Vascular Neoplasms; Vincristine; Vision Disorders
Life Sciences | Medicine and Health Sciences
PURPOSE: To describe the clinical course of a case of intravascular lymphoma. DESIGN: Case report.
METHODS: Retrospective chart review.
RESULTS: A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints.
CONCLUSIONS: Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.
Rights and Permissions
Citation: Ocul Immunol Inflamm. 2008 May-Jun;16(3):123-6. Link to article on publisher's site
DOI of Published Version
Ocular immunology and inflammation
Pahk, Patricia J.; Todd, Derrick James; Blaha, Gregory R.; Soukiasian, Sarkis H.; Landmann, Dan S.; Craven, Donald E.; Tronic, Bruce S.; Zabar, Yuval; and Marx, Jeffrey L., "Intravascular lymphoma masquerading as Vogt-Koyanagi-Harada syndrome" (2008). GSBS Student Publications. 1524.