GSBS Student Publications

Title

ATP-dependent chromatin remodeling

UMMS Affiliation

Graduate School of Biomedical Sciences; Program in Molecular Medicine; Program in Gene Function and Expression

Date

1-12-2005

Document Type

Article

Medical Subject Headings

Adenosine Triphosphate; Amino Acid Sequence; Animals; Chromatin; DNA-Binding Proteins; *Gene Expression Regulation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosomes; Protein Conformation; Sequence Alignment; Transcription Factors; Transcription, Genetic

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

The study of chromatin and how this dynamic structure modulates events in the eukaryotic nucleus has become an increasingly important topic in biomedical research. A large number of enzymes have been discovered that are responsible for modifying and altering chromatin structure, either globally or specifically at particular gene promoters or regions of the chromosome. This chapter provides an introduction to the structure of chromatin and then describes how special classes of enzymes modulate chromatin structure to allow access to DNA.

Rights and Permissions

Citation: Curr Top Dev Biol. 2005;65:115-48. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal Title

Current topics in developmental biology

PubMed ID

15642381