Dissertations and Theses from 2013
Identification and Analysis of the Domain Required for Trans-Acceleration Kinetics in the Human Glucose Transporter GLUT1: A Dissertation, Sabrina S. Vollers
Dissertations and Theses from 2012
Mechanisms of KRAS-Mediated Pancreatic Tumor Formation and Progression: A Dissertation, Victoria A. Appleman
Hepatitis C Virus Non-Structural Protein 3/4A: A Tale of Two Domains: A Dissertation, Cihan Aydin
The Subtype Specific and Cross-Reactive T Cell Responses to Influenza Viruses in Humans: A Dissertation, Jenny Aurielle B. Babon
Gene Expression and Profiling of Human Islet Cell Subtypes: A Master’s Thesis, David M. Blodgett
Understanding Small RNA Formation in Drosophila Melanogaster: A Dissertation, Elif Sarinay Cenik
Localization of Insulin Receptor Substrate-2 in Breast Cancer: A Dissertation, Jennifer L. Clark
Transcriptional Regulation of the Interleukin-8 Promoter by Multiple Dengue Viral Proteins: A Dissertation, Jacob M. Collins
Psychosocial and Behavioral Determinants of Medication Nonadherence Among African Americans with Hypertension: A Dissertation, Yendelela L. Cuffee
Runx1 C-terminal Domains During Hematopoietic Development and Leukemogenesis: A Dissertation, Christopher R. Dowdy
On the Source of Peptides for Major Histocompatibility Class I Antigen Presentation: A Dissertation, Diego José Farfán Arribas
Sequence and Target Specificity of the C. elegans Cell Fate Specification Factor POS-1: A Dissertation, Brian M. Farley
Role of Perivascular and Visceral Adipose Tissues in Murine Models of Obesity and Atherosclerosis: A Dissertation, Timothy P. Fitzgibbons
Building the Cell's Antenna: Protein Targeting to the Ciliary Membrane: A Dissertation, John A. Follit
Role of Glia in Sculpting Synaptic Connections at the Drosophila Neuromuscular Junction: A Dissertation, Yuly F. Fuentes Medel
Mdm2-p53 Signaling in Tissue Homeostasis and the DNA Damage Response: A Dissertation, Hugh S. Gannon
Analysis of Integrin α6β4 Function in Breast Carcinoma: A Dissertation, Kristin D. Gerson
Getting a Tight Grip on DNA: Optimizing Zinc Fingers for Efficient ZFN-Mediated Gene Editing: A Dissertation, Ankit Gupta
Characterization of Drug Resistance in Mycobacterium Tuberculosis via Saturating Mutagenesis of Drug Targets: A Master’s Thesis, Michelle J. Harris
Serotonin-Expressing Cells in the Corpus of the Stomach Originate from Bone Marrow: A Master’s Thesis, Brian T. Johnston
Gene Therapy for Very Long Chain Acyl-coA Dehydrogenase Deficiency Using Adeno-Associated Virus Vectors: A Dissertation, Allison M. Keeler
Glial Control of Synapse Assembly at the Drosophila Neuromuscular Junction: A Dissertation, Kimberly S. Kerr
The Role of Adaptor Protein Complex-3 Delta-Mediated HIV-1 Gag Trafficking in HIV-1 Replication: A Dissertation, Adonia Lee Kim
A Novel Communication Mechanism Between the Presynapse and Postsynapse Through Exosomes: A Dissertation, Ceren Korkut
Protein Ligand Interactions Probed by NMR: A Dissertation, Jennifer M. Laine
Catalytic Mechanisms in Sec7 and Vps9 Domain Exchange Factors for Arf and Rab GTPases: A Dissertation, Meng-Tse Lee
Studies on the Regulation of Cytoplasmic Polyadenylation Element-Binding Protein: A Dissertation, Chien-Ling Lin
Genetic Approaches to Study Transcriptional Activation and Tumor Suppression: A Dissertation, Ling Lin
Dissecting Somatic Cell Reprogramming by MicroRNAs and Small Molecules: A Dissertation, Zhonghan Li
Targeting the Histone Acetyl-Transferase, RTT109, for Novel Anti-Fungal Drug Development: A Dissertation, Jessica Lopes da Rosa-Spiegler
A Role for c-Jun Kinase (JNK) Signaling in Glial Engulfment of Degenerating Axons: A Dissertation, Jennifer M. MacDonald
RNA-Sensing Pattern Recognition Receptors and Their Effects on T-Cell Immune Responses: A Dissertation, Rachel F. Madera
Distinct Gene Circuits Control the Differentiation of Innate Versus Adaptive IL-17 Producing T Cells: A Dissertation, Nidhi Malhotra
Inflammation Inhibits Osteoblast-Mediated Bone Formation in Rheumatoid Arthritis and Regulates the Wnt and BMP Signaling Pathways: A Dissertation, Melissa M. Matzelle
Incidence, prognosis, and factors associated with cardiac arrest in patients hospitalized with acute coronary syndromes (the GRACE Registry): A master's thesis, David D. McManus
Characterization of New Factors in the 18S Nonfunctional Ribosomal RNA Decay Pathway in S. cerevisiae: A Dissertation, Christopher N. Merrikh
Slow-Cycling Cancer Cells: A Dissertation, Nathan F. Moore
Small Molecule Investigation of KCNQ Potassium Channels: A Dissertation, Karen Mruk
Lack of CFTR in CD3+ Lymphocytes Leads to Aberrant Cytokine Secretion and Hyper-Inflammatory Adaptive Immune Responses: A Master's Thesis, Christian Mueller
HIV-1 R5 Tropism: Determinants, Macrophages, and Dendritic Cells: A Dissertation, Thomas A. Musich
Molecular Mechanisms of Endocytosis: Trafficking and Functional Requirements for the Transferrin Receptor, Small Interfering RNAs and Dopamine Transporter: A Dissertation, Deanna M. Navaroli
TXNIP is a Mediator of ER Stress-Induced β-Cell Inflammation and Apoptosis: A Dissertation, Christine M. Oslowski
Contribution of WFS1 to Pancreatic Beta Cell Survival and Adaptive Alterations in WFS1 Deficiency: A Dissertation, Bryan M. O'Sullivan-Murphy
Transposition Driven Genomic Heterogeneity in the Drosophila Brain: A Dissertation, Paola N. Perrat
Maintaining the Balance: Coordinating Excitation and Inhibition in a Simple Motor Circuit: A Dissertation, Hilary A. Petrash
Therapeutic Silencing of Mutant Huntingtin by Targeting Single Nucleotide Polymorphisms: A Dissertation, Edith L. Pfister
Control of Bovine Papillomavirus E2 Function By Acetylation and the Novel E2 Interacting Protein RINT1: A Dissertation, Edward J. Quinlan
Antagonistic Pleiotropy: The Role of Smurf2 in Cancer and Aging: A Dissertation, Charusheila Ramkumar
Innate Signaling Pathways in the Maintenance of Serological Memory: A Dissertation, Forum M. Raval
Studies on Cellular Host Factors Involved in the HIV-1 Life Cycle: A Dissertation, Anna Kristina Serquiña
Molecular Studies of T Cell Recognition and Cross-Reactivity: A Dissertation, Zu T. Shen
Mechanical Activation of Valvular Interstitial Cell Phenotype: A Dissertation, Angela M. Throm Quinlan
An Extra-Embryonic Wnt Signaling Event Controls Gastrulation in Mice: A Dissertation, Giovane G. Tortelote
Origin of White and Brown Adipose Cells From Vascular Endothelium: A Dissertation, Khanh-Van T. Tran
Primary and Secondary Immune Responses During Sequential West Nile Virus and Japanese Encephalitis Virus Infections: A Dissertation, Derek W. Trobaugh
MicroRNA Markers of Acetaminophen Toxicity: A Master's Thesis, Jeanine Ward
The Role of Heterologous Immunity in Mediating Natural Resistance to Infection in Human Subjects: A Dissertation, Levi B. Watkin
Investigating the Roles of NEDD4.2s and Nef in the Release and Replication of HIV-1: A Dissertation, Eric R. Weiss
Chromatin Dynamics in Pluripotency and Differentiation: A Dissertation, Ozlem Yildirim
The Role of ITK in the Development of Gamma Delta NKT Cells: A Dissertation, Catherine C. Yin
The Molecular Mechanisms for Maintenance of Cancer Stem Cells in Chronic Myeloid Leukemia: A Dissertation, Haojian Zhang
Eaters of the Dead: How Glial Cells Respond to and Engulf Degenerating Axons in the CNS: A Dissertation, Jennifer S. Ziegenfuss
Dissertations and Theses from 2011
Use of Multinational Registries to Assess and Compare Outcomes of Patients with an Acute Coronary Syndrome: A Dissertation, Hamza H. Awad
Investigation of the C-Terminal Helix of HIV-1 Matrix: A Region Essential for Multiple Functions in the Viral Life Cycle: A Dissertation, Laura A. Brandano
Cooperativity in Mammalian RNA Silencing: A Dissertation, Jennifer A. Broderick
Intestine Homeostasis and the Role of Tumor Suppressor Gene 101 in Drosophila Melanogaster: A Dissertation, Madhurima Chatterjee
Asymmetric Inheritance and Post-mitotic Fate of Midbodies: A Dissertation, Chun-Ting Chen
Nuclear Import of Smad: A Dissertation, Xiaochu Chen
Critical Molecular Pathways in Cancer Stem Cells of Chronic Myeloid Leukemia: A Dissertation, Yaoyu Chen
Inflammation Alters Histone Methylation in the Central Nervous System: Implications for Neuropsychiatric Disease: A Dissertation, Caroline M. Connor
The Role of miR-21 and miR-31 in Cellular Responses Mediated by TGF-β: A Dissertation, Charisa L. Cottonham
Cellular and Molecular Mechanisms Driving Glial Engulfment of Degenerating Axons: A Dissertation, Johnna E. Doherty
Tyraminergic G Protein-Coupled Receptors Modulate Locomotion and Navigational Behavior In C. Elegans: A Dissertation, Jamie L. Donnelly
Quantitative Analysis of Novel Chemical and shRNA Based Methods to Increase Survival of Motor Neuron Protein Levels, Matthew C. Evans
Biomimetic Synthetic Tissue Scaffolds for Bone Regeneration: A Dissertation, Tera M. Filion Potts
Factors Associated with Ordering and Completion of Laboratory Monitoring Tests for High-Risk Medications in the Ambulatory Setting: A Dissertation, Shira H. Fischer
Identification of a Command Neuron Directing the Expression of Feeding Behavior in Drosophila melanogaster, Thomas F. Flood
Blocking the Notch Pathway with Gamma-Secretase Inhibitors Enhances Temozolomide Treatment of Gliomas through Therapy-Induced Senescence: A Dissertation, Candace A. Gilbert
A Global Analysis of the Adaptations Required for Sterol Catabolism in Mycobacterium Tuberculosis: A Dissertation, Jennifer E. Griffin
Role of the Yeast Ste20 Protein Kinase Ortholog Map4k4 in Adipose Tissue Function: A Dissertation, Kalyani V. P. Guntur
Dissecting Signaling Pathways that Regulate Axonal Guidance Effects of Sonic Hedgehog: A Dissertation, Daorong Guo
M.tb Killing by Macrophage Innate Immune Mechanisms: A Dissertation, Michelle L. Hartman
Using Light to Observe and Control Cellular Function: Improving Bioluminescence Imaging and Photocontrol of Rho GTPase Activation States: A Dissertation, Katryn R. Harwood
Neuronal Nicotinic Acetylcholine Receptors: Molecular Targets for Alcoholism and Ethanol Reward: A Dissertation, Linzy M. Hendrickson
Regulation and Function of Neuronal Nicotinic Acetylcholine Receptors in Lung Cancer: A Dissertation, Ma. Reina D. Improgo
Molecular and Functional Properties of Transmitted HIV-1 Envelope Variants: A Dissertation, Michael G. Kishko
Dynamics of Erythropoietic Survival Pathways In Vivo: A Dissertation, Miroslav Koulnis
Molecular Mechanisms of piRNA Biogenesis and Function in Drosophila: A Dissertation, Chengjian Li
Neuronal Diversification in the Postembryonic Drosophila Brain: A Dissertation, Suewei Lin
Cooperating Events in Core Binding Factor Leukemia Development: A Dissertation, Dmitri Madera
Insulin Receptor Substrate-2 (IRS-2): A Novel Hypoxia-Responsive Gene in Breast Cancer: A Dissertation, Katerina Mardilovich
Cannabis Use and Bipolar Disorder: Bipolar Disorder Case Identification and Cannabis Use Risk Assessment: A Dissertation, Patrick J. McCabe