Management of recurrent hepatitis C after liver transplantation: a concise review
UMass Chan Affiliations
Department of Medicine, Division of GastroenterologyDocument Type
Journal ArticlePublication Date
2000-09-28Keywords
Antiviral AgentsDrug Therapy, Combination
Hepacivirus
Hepatitis C, Chronic
Humans
Interferon-alpha
Liver Transplantation
Prognosis
RNA, Viral
Recurrence
Ribavirin
Gastroenterology
Hepatology
Metadata
Show full item recordAbstract
Recurrent hepatitis C infection and subsequent graft failure are increasingly recognized problems after orthotopic liver transplantation. Although many prospective therapeutic, controlled trials in primary hepatitis C disease have been reported, large-scale studies are yet to be performed in patients with posttransplant recurrent hepatitis C after liver transplantation. In this review, we summarize the current literature on the therapeutic approaches for recurrent hepatitis C and discuss the results of published studies on therapy with ribavirin or interferon (IFN) alone and on combination therapy with IFN plus ribavirin. Further, we discuss results of prophylactic approaches to the problem of recurrent hepatitis C after transplant. Finally, we discuss additional aspects of anti-hepatitis C virus therapy after liver transplantation.Source
Am J Gastroenterol. 2000 Sep;95(9):2164-70. Link to article on publisher's siteDOI
10.1111/j.1572-0241.2000.02296.xPermanent Link to this Item
http://hdl.handle.net/20.500.14038/31103PubMed ID
11007212Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1111/j.1572-0241.2000.02296.x