Title
Shedding light on sperm pHertility
UMMS Affiliation
Department of Cell Biology
Date
2-11-2010
Document Type
Article
Medical Subject Headings
Animals; Humans; Hydrogen-Ion Concentration; Male; Membrane Potentials; Mice; *Sperm Capacitation; Spermatozoa
Disciplines
Cell Biology
Abstract
The acquisition of fertilization capacity by sperm is regulated by intracellular pH (pH(i)), but the transport pathways that regulate pH(i) are not well understood. Lishko et al. (2010) now report that Hv1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm.
Rights and Permissions
Citation: Cell. 2010 Feb 5;140(3):310-2. Link to article on publisher's site
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