Title

Shedding light on sperm pHertility

UMMS Affiliation

Department of Cell Biology

Date

2-11-2010

Document Type

Article

Medical Subject Headings

Animals; Humans; Hydrogen-Ion Concentration; Male; Membrane Potentials; Mice; *Sperm Capacitation; Spermatozoa

Disciplines

Cell Biology

Abstract

The acquisition of fertilization capacity by sperm is regulated by intracellular pH (pH(i)), but the transport pathways that regulate pH(i) are not well understood. Lishko et al. (2010) now report that Hv1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm.

Rights and Permissions

Citation: Cell. 2010 Feb 5;140(3):310-2. Link to article on publisher's site

Related Resources

Link to Article in PubMed