Department of Medicine, Division of Rheumatology
Medical Subject Headings
Musculoskeletal Diseases | Rheumatology | Skin and Connective Tissue Diseases
Relapsing polychondritis (RP) is a rare systemic autoimmune disease characterized by episodic, progressive inflammatory destruction of cartilage. It can occur as an overlap syndrome in patients with other rheumatologic conditions. The disease usually follows an indolent relapsing-remitting course, but occasionally it can progress rapidly and even cause death. Although auricular or nasal chondritis or peripheral arthritis without other significant organ involvement are usually treated with low-dose corticosteroids, other more severe disease manifestations may require treatment with high-dose corticosteroids or other immunosuppressive agents. Biological targeted therapies might prove to be effective treatments of this condition.
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Citation: Rheum Dis Clin North Am. 2013 May;39(2):263-76. doi: 10.1016/j.rdc.2013.03.002. Link to article on publisher's site
Chopra, Ratnesh; Cahudhary, Nida; and Kay, Jonathan, "Relapsing polychondritis" (2013). University of Massachusetts Medical School Faculty Publications. 65.