University of Massachusetts Medical School Faculty Publications


Acute kidney injury due to intravenous bleach injection

UMMS Affiliation

Department of Emergency Medicine; Department of Pathology; Division of Renal Medicine

Publication Date


Document Type



Acute Kidney Injury; Sodium Hypochlorite


Emergency Medicine | Female Urogenital Diseases and Pregnancy Complications | Male Urogenital Diseases | Medical Toxicology | Nephrology | Pathology


INTRODUCTION: Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis.

DISCUSSION: We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.

Rights and Permissions

Citation: J Med Toxicol. 2013 Mar;9(1):71-4. doi: 10.1007/s13181-012-0259-6. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal/Book/Conference Title

Journal of medical toxicology : official journal of the American College of Medical Toxicology

PubMed ID