University of Massachusetts Medical School Faculty Publications


Magnitude and Impact of Multimorbidity on Clinical Outcomes in Older Adults with Cardiovascular Disease: A Literature Review

UMMS Affiliation

Division of Geriatric Medicine, Department of Medicine; Department of Quantitative Health Sciences; Meyers Primary Care Institute

Publication Date


Document Type



Cardiology | Cardiovascular Diseases | Geriatrics


The authors aim to synthesize the current literature on the magnitude and impact of multimorbidity on clinical outcomes in older adults with cardiovascular disease (CVD). Most studies reported a significant association between the number of morbidities and the risk of dying. Multimorbidity was assessed either by counting the number of conditions or by use of the Charlson or Elixhauser indices. There are limited data available on the magnitude and impact of multimorbidity on clinical outcomes in patients with CVD and essentially no data on universal health outcomes (eg, health-related quality of life, symptom burden, and function).


Cardiovascular disease, Clinical outcomes, Elderly, Multimorbidity

Rights and Permissions

Citation: Clin Geriatr Med. 2016 May;32(2):227-46. doi: 10.1016/j.cger.2016.01.014. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal/Book/Conference Title

Clinics in geriatric medicine

PubMed ID