Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine
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Abstract
Metastasis, drug resistance and recurrence in cancer are regulated by the tumor microenvironment. This review describes recent advances in understanding how cancer cells respond to extracellular environmental cues via integrins, how to build engineered microenvironments to study these interactions in vitro and how nanomaterials can be used to detect and target tumor microenvironments.Source
Drug Discov Today. 2016 Sep;21(9):1489-94. doi: 10.1016/j.drudis.2016.05.011. Epub 2016 May 26. Link to article on publisher's siteDOI
10.1016/j.drudis.2016.05.011Permanent Link to this Item
http://hdl.handle.net/20.500.14038/28869PubMed ID
27238384Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/j.drudis.2016.05.011