Title

Dystrophic epidermolysis bullosa associated with amniotic band syndrome

UMMS Affiliation

Division of Dermatology; Department of Medicine; School of Medicine

Date

3-1-2014

Document Type

Article

Disciplines

Dermatology | Skin and Connective Tissue Diseases

Abstract

Amniotic band syndrome (ABS) is a term used to describe congenital anomalies that result from the entrapment of a fetus in fibrous bands. We describe two male infants born with features of dystrophic epidermolysis bullosa (DEB) and ABS. These cases add to the few previous reports of simultaneous DEB and ABS. Abnormal type VII collagen in anchoring structures of the amniotic epithelium is a proposed mechanism for loose amniotic bands that entangle the fetus, with an abnormality in the gene that encodes for type VII collagen.

Rights and Permissions

Citation: Pediatr Dermatol. 2014 Mar-Apr;31(2):212-6. doi: 10.1111/pde.12285. Epub 2014 Jan 3. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

24383893