Title

The deep penetrating nevus

UMMS Affiliation

School of Medicine; Division of Dermatology; Department of Pediatrics

Date

12-1-2014

Document Type

Article

Disciplines

Dermatology | Skin and Connective Tissue Diseases

Abstract

The deep penetrating nevus (DPN), also known as the plexiform spindle cell nevus, is a pigmented lesion that commonly arises on the head and neck in the first few decades of life. Histopathologically, the DPN is wedge-shaped and contains melanocytes that exhibit deep infiltration into the dermis. Given these features, DPN may clinically and histopathologically mimic malignant melanoma, sparking confusion about the appropriate evaluation and management of these lesions. The goal of this review is to summarize the clinical and histopathological features of DPN and to discuss diagnostic and treatment strategies for dermatologists.

Rights and Permissions

Citation: J Am Acad Dermatol. 2014 Dec;71(6):1234-40. doi: 10.1016/j.jaad.2014.07.026. Epub 2014 Aug 28. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Keywords

deep penetrating nevus, dermatopathology, malignant melanoma, melanocytic tumor of uncertain malignant potential, nevus with focal atypical epithelioid components, plexiform spindle cell nevus

PubMed ID

25175710