Title

Cytomegalovirus diaper dermatitis

UMMS Affiliation

Department of Medicine, Division of Dermatology

Date

3-1-1991

Document Type

Article

Medical Subject Headings

Acquired Immunodeficiency Syndrome; Cytomegalovirus Infections; Diaper Rash; Humans; Infant; Male; Skin Diseases, Infectious

Disciplines

Dermatology | Pediatrics | Skin and Connective Tissue Diseases

Abstract

Cytomegalovirus inclusions have been reported in perineal ulcers from immunosuppressed adults. The importance of this finding is unknown. We report the first pediatric case of cutaneous cytomegalovirus infection in an infant with congenital human immunodeficiency virus infection, presenting as a diaper dermatitis. Cytomegalovirus was cultured from the skin biopsy specimen, and characteristic inclusions were seen on hematoxylin-eosin-stained sections. Results of this biopsy specimen analysis prompted further investigation revealing disseminated cytomegalovirus infection, including retinitis. Aggressive pursuit of a pathogen in common conditions such as diaper dermatitis is strongly recommended in immunosuppressed pediatric patients.

Comments

Citation: Arch Dermatol. 1991 Mar;127(3):396-8. doi:10.1001/archderm.1991.01680030116017

At the time of publication, Mary E. Maloney was not yet affiliated with the University of Massachusetts Medical School.

Related Resources

Link to Article in PubMed