Title

Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment production

UMMS Affiliation

Department of Medicine, Division of Dermatology

Date

9-2010

Document Type

Letter to the Editor

Medical Subject Headings

Administration, Topical; Aminoquinolines; Biopsy, Needle; Female; Follow-Up Studies; Humans; Hutchinson's Melanotic Freckle; Immunohistochemistry; Melanoma, Amelanotic; Middle Aged; Neoplasm Recurrence, Local; Nose; Risk Assessment; Skin Neoplasms; Treatment Outcome

Disciplines

Dermatology | Skin and Connective Tissue Diseases

Abstract

A melanotic lentigo maligna (ALM) represents a small subset of lentigo maligna (LM) that lacks pigment. At least 2 cases of ALM responsive to imiquimod therapy with short-term follow-up have been reported. We report herein a case of ALM that failed to respond to imiquimod treatment. Furthermore, after therapy was initiated, the ALM began to produce pigment and transformed to LM.

Comments

Citation: Martires KJ, Capaldi L, Pattee SF, Maloney ME, Bordeaux JS. Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment production. Arch Dermatol. 2010 Sep;146(9):1047-8. doi: 10.1001/archdermatol.2010.237.

Related Resources

Link to Article in PubMed

PubMed ID

20855714