Launched in 1999, The Global Registry of Acute Coronary Events (GRACE) is an international database designed to track outcomes of patients presenting with acute coronary syndromes, including myocardial infarction or unstable angina. GRACE includes hospitals in North America, South America, Europe, Asia, Australia and New Zealand. A data coordinating center has been established in the Center for Outcomes Research at the University of Massachusetts Medical School. This collection showcases publications about the GRACE project and project research. See also the GRACE2 (Expanded GRACE) Publications collection.

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Publications from 2014

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Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score, Keith A. A. Fox, Gordon FitzGerald, Etienne Puymirat, Wei Huang, Kathryn Carruthers, Tabassome Simon, Pierre Coste, Jacques Monsegu, Phillippe Gabriel Steg, Nicolas Danchin, and Frederick A. Anderson Jr.

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Beta-blocker Use in ST-segment Elevation Myocardial Infarction in the Reperfusion Era (GRACE), Kay Lee Park, Robert J. Goldberg, Frederick A. Anderson Jr., Jose Lopez-Sendon, Gilles Montalescot, David Brieger, Kim A. Eagle, Allison Wyman, Joel M. Gore, and GRACE Investigators

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GRACE score predicts heart failure admission following acute coronary syndrome, David A. McAllister, Nynke Halbesma, Kathryn F. Carruthers, Martin Denvir, and Keith A. Fox

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Clinical characteristics and outcomes of acute coronary syndrome patients with left anterior hemiblock, Hanfei Zhang, Shaun G. Goodman, Gabriel P. Steg, Andrzej Budaj, Jose Lopez-Sendon, Paul Dorian, Thao Huynh, Iqwal Mangat, Graham C. Wong, Frederick A. Spencer, Andrew T. Yan, and Global Registry of Acute Coronary Events (GRACE) ECG Substudy Investigators and the Canadian ACS Registry Investigators

Publications from 2013

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Management and outcomes of patients presenting with STEMI by use of chronic oral anticoagulation: results from the GRACE registry, Alvaro Alonso, Joel M. Gore, Hamza H. Awad, Ann L. Quill, Gilles Montalescot, Frans Van de Werf, Dietrich C. Gulba, Keith A. A. Fox, Kim A. Eagle, Christopher B. Granger, Allison Wyman, Phillippe Gabriel Steg, and GRACE Investigators

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Young patients hospitalized with an acute coronary syndrome, Hamza H. Awad, David D. McManus, Frederick A. Anderson Jr., Joel M. Gore, and Robert J. Goldberg

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Treatment and outcomes of patients with suspected acute coronary syndromes in relation to initial diagnostic impressions (insights from the Canadian Global Registry of Acute Coronary Events [GRACE] and Canadian Registry of Acute Coronary Events [CANRACE]), Ravi R. Bajaj, Shaun G. Goodman, Raymond T. Yan, Alan J. Bagnall, Gabor Gyenes, Robert C. Welsh, Kim A. Eagle, David Brieger, Krishnan Ramanathan, Francois R. Grondin, and Andrew T. Yan

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Do clinical factors explain persistent sex disparities in the use of acute reperfusion therapy in STEMI in Sweden and Canada?, Nina Johnston, Anna Bornefalk-Hermansson, Karin Schenck-Gustafsson, Claes Held, Shaun G. Goodman, Andrew T. Yan, and Arlene S. Bierman

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Management and outcomes of non-ST elevation acute coronary syndromes in relation to previous use of antianginal therapies (from the Canadian Global Registry of Acute Coronary Events [GRACE] and Canadian Registry of Acute Coronary Events [CANRACE]), Jaskaran S. Kang, Shaun G. Goodman, Raymond T. Yan, Jose Lopez-Sendon, Yves Pesant, John J. Graham, David H. Fitchett, Graham C. Wong, Barry F. Rose, Frederick A. Spencer, and Andrew T. Yan

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Pre-hospital cardiac arrest in acute coronary syndromes: insights from the global registry of acute coronary events and the canadian registry of acute coronary events, Qin Li, Shaun G. Goodman, Raymond T. Yan, Joel M. Gore, Petr Polasek, Kevin Lai, Carolyn Baer, Robert J. Goldberg, Arnold Pinter, Kamran Ahmad, Jan M. Kornder, and Andrew T. Yan

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Treatment and outcomes of non-ST elevation acute coronary syndromes in relation to burden of pre-existing vascular disease, Michael Mohareb, Shaun G. Goodman, Raymond T. Yan, Deepak L. Bhatt, Basem Elbarouni, J. Paul DeYoung, Richard Gallo, Jan M. Kornder, Robert C. Welsh, Gustavo Saposnik, Barry Rose, Graham C. Wong, Francois R. Grondin, Andrew T. Yan, and Canadian GRACE/GRACE2/CANRACE Investigators

Publications from 2012

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Management and Outcome of Acute Coronary Syndrome Patients in Relation to Prior History of Atrial Fibrillation, Darar Al Khdair, Lamia Alshengeiti, Basem Elbarouni, Raymond T. Yan, Francois R. Grondin, Frederick A. Spencer, Sven Pallie, David Brieger, Kim A. Eagle, Iqwal Mangat, Sheldon M. Singh, Shaun G. Goodman, Andrew T. Yan, Global Registry of Acute Coronary Events (GRACE/GRACE2) Investigators, and Canadian Registry of Coronary Events (CANRACE) Investigators

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The Association Between Prior Use of Aspirin and/or Warfarin and the In-hospital Management and Outcomes in Patients Presenting With Acute Coronary Syndromes: Insights From the Global Registry of Acute Coronary Events (GRACE), Hani Amad, Andrew T. Yan, Raymond T. Yan, Thao Huynh, Joel M. Gore, Gilles Montalescot, J. Paul DeYoung, Richard Gallo, Barry Rose, Phillippe Gabriel Steg, and Shaun G. Goodman

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Cardiogenic shock complicating acute coronary syndromes: insights from the Global Registry of Acute Coronary Events, Hamza H. Awad, Frederick A. Anderson Jr., Joel M. Gore, Shaun G. Goodman, and Robert J. Goldberg

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Reperfusion Strategies and Outcomes of ST-Segment Elevation Myocardial Infarction Patients in Canada: Observations From the Global Registry of Acute Coronary Events (GRACE) and the Canadian Registry of Acute Coronary Events (CANRACE), Andrew Czarnecki, Robert C. Welsh, Raymond T. Yan, J. Paul DeYoung, Richard Gallo, Barry Rose, Francois R. Grondin, Jan Kornder, Graham C. Wong, Keith A. A. Fox, Joel M. Gore, Shaun G. Goodman, and Andrew T. Yan

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Temporal Patterns of Lipid Testing and Statin Therapy in Acute Coronary Syndrome Patients (from the Canadian GRACE Experience), Basem Elbarouni, Behnam Banihashemi, Raymond T. Yan, Robert C. Welsh, Jan Kornder, Graham C. Wong, Frederick A. Anderson Jr., Frederick A. Spencer, Francois R. Grondin, Shaun G. Goodman, Andrew T. Yan, Canadian Global Registry of Acute Coronary Events (GRACE/GRACE2) Investigators, and Canadian Registry of Acute Coronary Events (CANRACE) Investigators

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Comparison of acute coronary syndrome in patients receiving versus not receiving chronic dialysis (from the Global Registry of Acute Coronary Events [GRACE] Registry), Hitinder S. Gurm, Joel M. Gore, Frederick A. Anderson Jr., Allison Wyman, Keith A. A. Fox, Phillippe Gabriel Steg, and Kim A. Eagle

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Incidence, prognosis, and factors associated with cardiac arrest in patients hospitalized with acute coronary syndromes (the Global Registry of Acute Coronary Events Registry), David D. McManus, Farhan Aslam, Parag Goyal, Robert J. Goldberg, Wei Huang, and Joel M. Gore

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Trends in atrial fibrillation in patients hospitalized with an acute coronary syndrome, David D. McManus, Wei Huang, Kunal V. Domakonda, Jeanine Ward, Jane S. Saczynski, Joel M. Gore, and Robert J. Goldberg

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Risk-Prediction Model for Ischemic Stroke in Patients Hospitalized With an Acute Coronary Syndrome (from the Global Registry of Acute Coronary Events [GRACE]), Kay Lee Park, Andrzej Budaj, Robert J. Goldberg, Frederick A. Anderson Jr., Giancarlo Agnelli, Brian M. Kennelly, Enrique P. Gurfinkel, Gordon Fitzgerald, Joel M. Gore, and GRACE Investigators

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Bridging the gender gap: Insights from a contemporary analysis of sex-related differences in the treatment and outcomes of patients with acute coronary syndromes, Stephanie Poon, Shaun G. Goodman, Raymond T. Yan, Raffaele Bugiardini, Arlene S. Bierman, Kim A. Eagle, Nina Johnston, Thao Huynh, Francois R. Grondin, Karin Schenck-Gustafsson, and Andrew T. Yan

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Non-alcoholic fatty liver disease and outcomes in persons with acute coronary syndromes: insights from the GRACE-ALT analysis, Lavanya Ravichandran, Shaun G. Goodman, Andrew T. Yan, Aurora Mendelsohn, and Joel G. Ray

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Trends and predictors of rehospitalisation following an acute coronary syndrome: report from the Australian and New Zealand population of the Global Registry of Acute Coronary Events (GRACE), Prashanthi V. Sangu, Isuru Ranasinghe, Bernadette Aliprandi-Costa, Gerard Devlin, John Elliot, Jeffrey Lefkovits, and David Brieger

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Relation between previous Angiotensin-converting enzyme inhibitor use and in-hospital outcomes in acute coronary syndromes, Sheldon M. Singh, Shaun G. Goodman, Raymond T. Yan, Jean-Pierre Dery, Graham C. Wong, Richard Gallo, Francois R. Grondin, Kevin Lai, Jose Lopez-Sendon, Keith A. A. Fox, and Andrew T. Yan

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Influence of 23 coronary artery disease variants on recurrent myocardial infarction or cardiac death: the GRACE Genetics Study, Els Wauters, Kathryn F. Carruthers, Ian Buysschaert, Donald R. Dunbar, Gilian Peuteman, Ann Belmans, Andrzej Budaj, Frans Van de Werf, Diether Lambrechts, and Keith A. A. Fox

Publications from 2011

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Management and outcomes of patients with acute coronary syndromes in Australia and New Zealand, 2000-2007, Bernadette Aliprandi-Costa, Isuru Ranasinghe, Vincent Chow, Shruti Kapila, Craig Juergens, Gerard Devlin, John Elliott, Jeff Lefkowitz, and David Brieger

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Comparison of Characteristics, Management Practices, and Outcomes of Patients Between the Global Registry and the Gulf Registry of Acute Coronary Events, Hamza H. Awad, Mohammad Zubaid, Alawi A. Alsheikh-Ali, Jassim Al Suwaidi, Frederick A. Anderson Jr., Joel M. Gore, and Robert J. Goldberg

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Outcomes from patients with multi-vessel disease following primary PCI: staged PCI imparts very low mortality, Kurt G. Barringhaus, Kay Lee Park, David D. McManus, Phillippe Gabriel Steg, Gilles Montalescot, Frans Van de Werf, Jose Lopez-Sendon, Gordon FitzGerald, and Joel M. Gore

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Quantitative troponin and death, cardiogenic shock, cardiac arrest and new heart failure in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS): insights from the Global Registry of Acute Coronary Events, Sanjit S. Jolly, Heather Shenkman, David Brieger, Keith A. A. Fox, Andrew T. Yan, Kim A. Eagle, Phillippe Gabriel Steg, Ki-Dong Lim, Ann L. Quill, and Shaun G. Goodman

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Use of Clopidogrel Post-Coronary Artery Bypass Surgery in Canadian Patients With Acute Coronary Syndromes, Ahmed Krimly, Raymond T. Yan, Andrew T. Yan, J. Paul DeYoung, Richard Gallo, Gabriel Steg, John Eikelboom, Joel M. Gore, Keith A. A. Fox, David Fitchett, Mackenzie A. Quantz, and Shaun G. Goodman

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Risk Stratification in the Setting of Non-ST Elevation Acute Coronary Syndromes 1999-2007, Isuru Ranasighe, Bernadette Alprandi-Costa, Vincent Chow, John M. Elliott, Jonathon Waites, John T. Counsell, Jose Lopez-Sendon, Alvaro Avezum, Shaun G. Goodman, Christopher B. Granger, and David Brieger

Publications from 2010

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Chronic nitrate therapy is associated with different presentation and evolution of acute coronary syndromes: insights from 52,693 patients in the Global Registry of Acute Coronary Events, Giuseppe Ambrosio, Maurizio Del Pinto, Isabella Tritto, Giancarlo Agnelli, Maurizio Bentivoglio, Cinzia Zuchi, Frederick A. Anderson Jr., Joel M. Gore, Jose Lopez-Sendon, Allison Wyman, Brian M. Kennelly, and Keith A. A. Fox

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A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study, Ian Buysschaert, Kathryn F. Carruthers, Donald R. Dunbar, Gilian Peuteman, Ernst Rietzschel, Ann Belmans, Ann Hedley, Tim De Meyer, Andrzej Budaj, Frans Van de Werf, Diether Lambrechts, and Keith A. A. Fox

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Six-month survival benefits associated with clinical guideline recommendations in acute coronary syndromes, D. P. Chew, Frederick A. Anderson Jr., Alvaro Avezum, Kim A. Eagle, Gordon Fitzgerald, Joel M. Gore, Rebecca Dedrick, and David Brieger

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Underestimated and under-recognized: the late consequences of acute coronary syndrome (GRACE UK-Belgian Study), Keith A. A. Fox, Kathryn F. Carruthers, Donald R. Dunbar, Catriona Graham, Jonathan R. Manning, Herbert De Raedt, Ian Buysschaert, Diether Lambrechts, and Frans Van de Werf

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Has the frequency of bleeding changed over time for patients presenting with an acute coronary syndrome? The global registry of acute coronary events, Keith A. A. Fox, Kathryn F. Carruthers, Phillippe Gabriel Steg, Alvaro Avezum, Christopher B. Granger, Gilles Montalescot, Shaun G. Goodman, Joel M. Gore, Ann L. Quill, and Kim A. Eagle

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The Global Registry of Acute Coronary Events, 1999 to 2009--GRACE, Keith A. A. Fox, Kim A. Eagle, Joel M. Gore, Phillippe Gabriel Steg, and Frederick A. Anderson Jr.

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Factors related to heart rupture in acute coronary syndromes in the Global Registry of Acute Coronary Events, Jose Lopez-Sendon, Enrique P. Gurfinkel, Esteban Lopez de Sa, Giancarlo Agnelli, Joel M. Gore, Phillippe Gabriel Steg, Kim A. Eagle, Jose Ruiz Cantadore, Gordon FitzGerald, and Christopher B. Granger

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Age and sex differences, and changing trends, in the use of evidence-based therapies in acute coronary syndromes: perspectives from a multinational registry., Hoa L. Nguyen, Robert J. Goldberg, Joel M. Gore, Keith A. A. Fox, Kim A. Eagle, Enrique P. Gurfinkel, Frederick A. Spencer, George W. Reed Ph.D., Ann L. Quill, and Frederick A. Anderson Jr.

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Can an elderly woman's heart be too strong? Increased mortality with high versus normal ejection fraction after an acute coronary syndrome. The Global Registry of Acute Coronary Events, Fadi A. Saab, Phillippe Gabriel Steg, Alvaro Avezum, Jose Lopez-Sendon, Frederick A. Anderson Jr., Wei Huang, and Kim A. Eagle

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Delay to reperfusion in patients with acute myocardial infarction presenting to acute care hospitals: an international perspective, Frederick A. Spencer, Gilles Montalescot, Keith A. A. Fox, Shaun G. Goodman, Christopher B. Granger, Robert J. Goldberg, Gustavo B.F. Oliveira, Frederick A. Anderson, Kim A. Eagle, Gordon Fitzgerald, and Joel M. Gore

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Recurrent ischemia across the spectrum of acute coronary syndromes: prevalence and prognostic significance of (re-)infarction and ST-segment changes in a large contemporary registry, Andrew T. Yan, Phillippe Gabriel Steg, Gordon Fitzgerald, Laurent J. Feldman, Kim A. Eagle, Joel M. Gore, Frederick A. Anderson Jr., Jose Lopez-Sendon, Enrique P. Gurfinkel, David Brieger, and Shaun G. Goodman

Publications from 2009

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Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global Registry of Acute Coronary Events. 2004, David Brieger, Kim A. Eagle, Shaun G. Goodman, Phillippe Gabriel Steg, Andrzej Budaj, Kami White, Gilles Montalescot, and GRACE Investigators

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Predicting freedom from clinical events in non-ST-elevation acute coronary syndromes: the Global Registry of Acute Coronary Events, David Brieger, Keith A. A. Fox, Gordon Fitzgerald, Kim A. Eagle, Andrzej Budaj, Alvaro Avezum, Christopher B. Granger, B. Costa, Frederick A. Anderson Jr., and Phillippe Gabriel Steg

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Sex-related differences in the presentation, treatment and outcomes among patients with acute coronary syndromes: the Global Registry of Acute Coronary Events, S. Dey, Marcus D. Flather, G. Devlin, David Brieger, Enrique P. Gurfinkel, Phillippe Gabriel Steg, Gordon Fitzgerald, Elizabeth A. Jackson, and Kim A. Eagle

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Prehospital Delay in Patients With Acute Coronary Syndromes (from the Global Registry of Acute Coronary Events [GRACE]), Robert J. Goldberg, Frederick A. Spencer, Keith A. A. Fox, David Brieger, Phillippe Gabriel Steg, Enrique P. Gurfinkel, Rebecca Dedrick, and Joel M. Gore

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Thrombocytopenia in patients with an acute coronary syndrome (from the Global Registry of Acute Coronary Events [GRACE]), Joel M. Gore, Frederick A. Spencer, Enrique P. Gurfinkel, Jose Lopez-Sendon, Phillippe Gabriel Steg, Christopher B. Granger, Gordon FitzGerald, and Giancarlo Agnelli

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Predictors and implications of Q-waves in ST-elevation acute coronary syndromes, Troy LaBounty, Hitinder S. Gurm, Shaun G. Goodman, Gilles Montalescot, Jose Lopez-Sendon, Ann L. Quill, and Kim A. Eagle

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In-hospital outcomes associated with fibrinolytic and thienopyridine use in patients with ST-segment elevation acute myocardial infarction. The global registry of acute coronary events, Jose Lopez-Sendon, Omar H. Dabbous, Esteban Lopez de Sa, Martin K. Stiles, Joel M. Gore, David Brieger, Frans Van de Werf, Andrzej Budaj, Enrique P. Gurfinkel, and Keith A. A. Fox

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Reperfusion in patients with renal dysfunction after presentation with ST-segment elevation or left bundle branch block: GRACE (Global Registry of Acute Coronary Events), Caroline Medi, Gilles Montalescot, Andrzej Budaj, Keith A. A. Fox, Jose Lopez-Sendon, Gordon Fitzgerald, and David Brieger

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Unprotected left main revascularization in patients with acute coronary syndromes, Gilles Montalescot, David Brieger, Kim A. Eagle, Frederick A. Anderson Jr., Gordon Fitzgerald, Michael S. Lee, Phillippe Gabriel Steg, Alvaro Avezum, Shaun G. Goodman, and Joel M. Gore

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Validity of a risk-prediction tool for hospital mortality: the Global Registry of Acute Coronary Events, Karen S. Pieper, Joel M. Gore, Gordon Fitzgerald, Christopher B. Granger, Robert J. Goldberg, Phillippe Gabriel Steg, Kim A. Eagle, Frederick A. Anderson Jr., Andrzej Budaj, and Keith A. A. Fox

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Pulmonary artery catheterization in patients with acute coronary syndromes, Christopher P. Ruisi, Robert J. Goldberg, Brian M. Kennelly, Shaun G. Goodman, Jose Lopez-Sendon, Christopher B. Granger, Alvaro Avezum, Kim A. Eagle, Gordon Fitzgerald, and Joel M. Gore

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Association of elevated fasting glucose with increased short-term and 6-month mortality in ST-segment elevation and non-ST-segment elevation acute coronary syndromes: the Global Registry of Acute Coronary Events, Peter R. Sinnaeve, Phillippe Gabriel Steg, Keith A. A. Fox, Frans Van de Werf, Gilles Montalescot, Christopher B. Granger, Elias Knobel, Frederick A. Anderson Jr., Omar H. Dabbous, and Alvaro Avezum

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Risk stratification in non-ST-segment elevation acute coronary syndromes: troponin alone is not enough, Phillippe Gabriel Steg, Gordon Fitzgerald, and Keith A. A. Fox

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Mortality following placement of drug-eluting and bare-metal stents for ST-segment elevation acute myocardial infarction in the Global Registry of Acute Coronary Events, Phillippe Gabriel Steg, Keith A. A. Fox, Kim A. Eagle, Mark I. Furman, Frans Van de Werf, Gilles Montalescot, Shaun G. Goodman, Alvaro Avezum, Wei Huang, and Joel M. Gore

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Delay to angiography and outcomes following presentation with high-risk, non-ST-elevation acute coronary syndromes: results from the Global Registry of Acute Coronary Events, Neil Swanson, Gilles Montalescot, Kim A. Eagle, Shaun G. Goodman, Wei Huang, David Brieger, and G. Devlin

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Impact of prior statin therapy on arrhythmic events in patients with acute coronary syndromes (from the Global Registry of Acute Coronary Events [GRACE]), Ameeth Vedre, Hitinder S. Gurm, James B. Froehlich, Eva M. Kline-Rogers, Gilles Montalescot, Joel M. Gore, David Brieger, Ann L. Quill, and Kim A. Eagle

Publications from 2008

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Magnitude and prognosis associated with ventricular arrhythmias in patients hospitalized with acute coronary syndromes (from the GRACE Registry), Alvaro Avezum, Leopoldo S. Piegas, Robert J. Goldberg, David Brieger, Martin K. Stiles, Richard Paolini, Wei Huang, and Joel M. Gore

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Outcomes with the use of glycoprotein IIb/IIIa inhibitors in non-ST-segment elevation acute coronary syndromes, Omar H. Dabbous, Frederick A. Anderson Jr., Joel M. Gore, Kim A. Eagle, Keith A. A. Fox, Rajendra H. Mehta, Robert J. Goldberg, Giancarlo Agnelli, and Phillippe Gabriel Steg

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Management and 6-month outcomes in elderly and very elderly patients with high-risk non-ST-elevation acute coronary syndromes: The Global Registry of Acute Coronary Events, Gerard Devlin, Joel M. Gore, John M. Elliott, Namal Wijesinghe, Kim A. Eagle, Alvaro Avezum, Wei Huang, and David Brieger

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Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go, Kim A. Eagle, Brahmajee K. Nallamothu, Rajendra H. Mehta, Christopher B. Granger, Phillippe Gabriel Steg, Frans Van de Werf, Jose Lopez-Sendon, Shaun G. Goodman, Ann L. Quill, and Keith A. A. Fox

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Time course of events in acute coronary syndromes: implications for clinical practice from the GRACE registry, Keith A. A. Fox, Frederick A. Anderson Jr., Shaun G. Goodman, Phillippe Gabriel Steg, Karen S. Pieper, Ann L. Quill, and Joel M. Gore

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Impact of in-hospital revascularization on survival in patients with non-ST-elevation acute coronary syndrome and congestive heart failure, Phillippe Gabriel Steg, Arthur Kerner, Frans Van de Werf, Jose Lopez-Sendon, Joel M. Gore, Gordon Fitzgerald, Laurent J. Feldman, Frederick A. Anderson Jr., and Alvaro Avezum

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Bleeding events with antithrombotic therapy in patients with unstable angina or non-ST-segment elevation myocardial infarction; insights from a large clinical practice registry (GRACE), Martin K. Stiles, Omar H. Dabbous, and Keith A. A. Fox

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Usefulness of quantitative versus qualitative ST-segment depression for risk stratification of non-ST elevation acute coronary syndromes in contemporary clinical practice, Raymond T. Yan, Andrew T. Yan, Christopher B. Granger, Jose Lopez-Sendon, David Brieger, Brian M. Kennelly, Andrzej Budaj, Phillippe Gabriel Steg, Alina A. Georgescue, Quamrul Hassan, Shaun G. Goodman, and GRACE Electrocardiogram Substudy Group

Publications from 2007

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Predicting coronary artery bypass graft surgery in acute coronary syndromes, David Brieger, Maros Elsik, Joel M. Gore, Elias Knobel, Amit Nussbacher, Leopoldo S. Piegas, Jeanna Allegrone, Frederick A. Anderson Jr., and Alvaro Avezum

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Interactions between heparins, glycoprotein IIb/IIIa antagonists, and coronary intervention. The Global Registry of Acute Coronary Events (GRACE), David Brieger, Frans Van de Werf, Alvaro Avezum, Gilles Montalescot, Brian M. Kennelly, Christopher B. Granger, Shaun G. Goodman, Omar H. Dabbous, and Giancarlo Agnelli

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Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE), Keith A. A. Fox, Frederick A. Anderson Jr., Omar H. Dabbous, Phillippe Gabriel Steg, Jose Lopez-Sendon, Frans Van de Werf, Andrzej Budaj, Enrique P. Gurfinkel, Shaun G. Goodman, and David Brieger

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Decline in rates of death and heart failure in acute coronary syndromes, 1999-2006, Keith A. A. Fox, Phillippe Gabriel Steg, Kim A. Eagle, Shaun G. Goodman, Frederick A. Anderson Jr., Christopher B. Granger, Marcus D. Flather, Andrzej Budaj, Ann L. Quill, and Joel M. Gore

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Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century: a multinational perspective, Robert J. Goldberg, Frederick A. Spencer, Phillippe Gabriel Steg, Marcus Flather, Gilles Montalescot, Enrique P. Gurfinkel, Brian M. Kennelly, Shaun G. Goodman, Rebecca Dedrick, and Joel M. Gore

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Use of heparins in Non-ST-elevation acute coronary syndromes, Joel M. Gore, Frederick A. Spencer, Robert J. Goldberg, Brian M. Kennelly, Keith A. A. Fox, Jeanna Allegrone, Kim A. Eagle, Frederick A. Anderson Jr., and Phillippe Gabriel Steg

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Invasive vs non-invasive treatment in acute coronary syndromes and prior bypass surgery, Enrique P. Gurfinkel, Ricardo Perez de la Hoz, Viviana M. Brito, Ernesto Duronto, Omar H. Dabbous, Joel M. Gore, and Frederick A. Anderson Jr.

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Impact of prior peripheral arterial disease and stroke on outcomes of acute coronary syndromes and effect of evidence-based therapies (from the Global Registry of Acute Coronary Events), Debabrata Mukherjee, Kim A. Eagle, Eva M. Kline-Rogers, Laurent J. Feldman, Jean-Michel Juliard, Giancarlo Agnelli, Andrzej Budaj, Alvaro Avezum, Jeanna Allegrone, Gordon Fitzgerald, and Phillippe Gabriel Steg

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Relationship of treatment delays and mortality in patients undergoing fibrinolysis and primary percutaneous coronary intervention. The Global Registry of Acute Coronary Events, Brahmajee K. Nallamothu, Keith A. A. Fox, Brian M. Kennelly, Frans Van de Werf, Joel M. Gore, Phillippe Gabriel Steg, Christopher B. Granger, Omar H. Dabbous, Eva M. Kline-Rogers, and Kim A. Eagle

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Combining warfarin and antiplatelet therapy after coronary stenting in the Global Registry of Acute Coronary Events: is it safe and effective to use just one antiplatelet agent, Michael C. Nguyen, Yean L. Lim, Antony Walton, Jeffrey Lefkovits, Giancarlo Agnelli, Shaun G. Goodman, Andrzej Budaj, Dietrich C. Gulba, Jeanna Allegrone, and David Brieger

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Use of proven therapies in non-ST-elevation acute coronary syndromes according to evidence-based risk stratification, Gustavo B.F. Oliveira, Alvaro Avezum, Frederick A. Anderson Jr., Andrzej Budaj, Omar H. Dabbous, Shaun G. Goodman, Phillippe Gabriel Steg, Robert J. Goldberg, David Brieger, Keith A. A. Fox, Joel M. Gore, and Christopher B. Granger

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Risk prediction in patients presenting with suspected cardiac pain: the GRACE and TIMI risk scores versus clinical evaluation, G. Ramsay, M. Podogrodzka, C. McClure, and Keith A. A. Fox

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Comparison of utilization of statin therapy at hospital discharge and six-month outcomes in patients with an acute coronary syndrome and serum low-density lipoprotein ≥100 mg/dl versus <100 mg>/dl, Frederick A. Spencer, Robert J. Goldberg, Joel M. Gore, Keith A. A. Fox, Alvaro Avezum, Giancarlo Agnelli, Leonard Kritharides, Frederick A. Anderson, Shaun G. Goodman, Gordon Fitzgerald, Jeanna Allegrone, and David Brieger

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Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction, Frederick A. Spencer, Mauro Moscucci, Christopher B. Granger, Joel M. Gore, Robert J. Goldberg, Phillippe Gabriel Steg, Shaun G. Goodman, Andrzej Budaj, Gordon Fitzgerald, and Keith A. A. Fox

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External validity of clinical trials in acute myocardial infarction, Phillippe Gabriel Steg, Jose Lopez-Sendon, Esteban Lopez de Sa, Shaun G. Goodman, Joel M. Gore, Frederick A. Anderson Jr., Dominique Himbert, Jeanna Allegrone, and Frans Van de Werf

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Relationship of ST elevation in lead aVR with angiographic findings and outcome in non-ST elevation acute coronary syndromes, Andrew T. Yan, Raymond T. Yan, Brian M. Kennelly, Frederick A. Anderson Jr., Andrzej Budaj, Jose Lopez-Sendon, David Brieger, Jeanna Allegrone, Phillippe Gabriel Steg, and Shaun G. Goodman

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Differences between local hospital and core laboratory interpretation of the admission electrocardiogram in patients with acute coronary syndromes and their relation to outcome, Raymond T. Yan, Andrew T. Yan, Jeanna Allegrone, Jose Lopez-Sendon, Christopher B. Granger, Joel M. Gore, Andrzej Budaj, Alina A. Georgescue, Quamrul Hassan, Janna Luchansky, Frans Van de Werf, and Shaun G. Goodman

Publications from 2006

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Patterns of use and potential impact of early beta-blocker therapy in non-ST-elevation myocardial infarction with and without heart failure: the Global Registry of Acute Coronary Events, Michael Emery, Jose Lopez-Sendon, Phillippe Gabriel Steg, Frederick A. Anderson Jr., Omar H. Dabbous, Aliocha Scheuble, Kim A. Eagle, and GRACE Investigators

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Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE), Keith A. A. Fox, Omar H. Dabbous, Robert J. Goldberg, Karen S. Pieper, Kim A. Eagle, Frans Van de Werf, Alvaro Avezum, Shaun G. Goodman, Marcus D. Flather, Frederick A. Anderson Jr., and Christopher B. Granger

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Association of peripheral artery disease with treatment and outcomes in acute coronary syndromes. The Global Registry of Acute Coronary Events (GRACE), James B. Froehlich, Debabrata Mukherjee, Alvaro Avezum, Andrzej Budaj, Eva M. Kline-Rogers, José López-Sendón, Jeanna Allegrone, Kim A. Eagle, Rajendra H. Mehta, Robert J. Goldberg, and GRACE Investigators

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The diagnostic and prognostic impact of the redefinition of acute myocardial infarction: lessons from the Global Registry of Acute Coronary Events (GRACE), Shaun G. Goodman, Phillippe Gabriel Steg, Kim A. Eagle, Keith A. A. Fox, Jose Lopez-Sendon, Gilles Montalescot, Andrzej Budaj, Brian M. Kennelly, Joel M. Gore, Jeanna Allegrone, Christopher B. Granger, Enrique P. Gurfinkel, and GRACE Investigators

Publications from 2005

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Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE), Alvaro Avezum, Marcia Makdisse, Frederick A. Spencer, Joel M. Gore, Keith A. A. Fox, Gilles Montalescot, Kim A. Eagle, Kami White, Rajendra H. Mehta, Elias Knobel, Jean-Philippe Collet, and GRACE Investigators

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Magnitude of and risk factors for in-hospital and postdischarge stroke in patients with acute coronary syndromes: findings from a Global Registry of Acute Coronary Events, Andrzej Budaj, Katarzyna Flasinska, Joel M. Gore, Frederick A. Anderson Jr., Omar H. Dabbous, Frederick A. Spencer, Robert J. Goldberg, and Keith A. A. Fox

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Contemporary management of acute coronary syndromes: does the practice match the evidence? The global registry of acute coronary events (GRACE), Kathryn F. Carruthers, Omar H. Dabbous, Marcus D. Flather, I. Starkey, A. Jacob, D. Macleod, Keith A. A. Fox, and GRACE Investigators

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Non-ST-segment elevation acute coronary syndrome in patients with renal dysfunction: benefit of low-molecular-weight heparin alone or with glycoprotein IIb/IIIa inhibitors on outcomes. The Global Registry of Acute Coronary Events, Jean-Philippe Collet, Gilles Montalescot, Giancarlo Agnelli, Frans Van de Werf, Enrique P. Gurfinkel, José López-Sendón, Christopher V. Laufenberg, Martin Klutman, Neelam Gowda, Dietrich C. Gulba, and GRACE Investigators

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Management and outcomes of lower risk patients presenting with acute coronary syndromes in a multinational observational registry, G. Devlin, Frederick A. Anderson Jr., S. Heald, José López-Sendón, Alvaro Avezum, John M. Elliott, Omar H. Dabbous, David Brieger, and GRACE Investigators

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Medication performance measures and mortality following acute coronary syndromes, Christopher B. Granger, Phillippe Gabriel Steg, Eric D. Peterson, José López-Sendón, Frans Van de Werf, Eva M. Kline-Rogers, Jeanna Allegrone, Omar H. Dabbous, Werner Klein, Keith A. A. Fox, Kim A. Eagle, and GRACE Investigators

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Socio economic crisis and mortality. Epidemiological testimony of the financial collapse of Argentina, Enrique P. Gurfinkel, Gerardo E. Bozovich, Omar H. Dabbous, Branco Mautner, and Frederick A. Anderson Jr.

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Cigarette smoking and acute coronary syndromes: a multinational observational study, Dominique Himbert, Martin Klutman, Phillippe Gabriel Steg, Kami White, Dietrich C. Gulba, and GRACE Investigators

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Treating patients with acute coronary syndromes with aggressive antiplatelet therapy (from the Global Registry of Acute Coronary Events), Michael J. Lim, Kim A. Eagle, Joel M. Gore, Frederick A. Anderson Jr., Omar H. Dabbous, Rajendra H. Mehta, Christopher B. Granger, Keith A. A. Fox, Frederick A. Spencer, and Robert J. Goldberg

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Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: perspectives from a large multinational registry, Michael J. Lim, Frederick A. Spencer, Joel M. Gore, Omar H. Dabbous, Giancarlo Agnelli, Eva M. Kline-Rogers, Donna Dibenedetto, Kim A. Eagle, and Rajendra H. Mehta

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Circulating secretory phospholipase A2 activity predicts recurrent events in patients with severe acute coronary syndromes, Ziad Mallat, Phillippe Gabriel Steg, Joelle Benessiano, Marie-Laure Tanguy, Keith A. A. Fox, Jean-Philippe Collet, Omar H. Dabbous, Patrick Henry, Kathryn F. Carruthers, Anne Dauphin, Carla Sibella Arguelles, Joelle Masliah, Benedicte Hugel, Gilles Montalescot, Jean-Marie Freyssinet, Bernard Asselain, and Alain Tedgui

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Relation of timing of cardiac catheterization to outcomes in patients with non-ST-segment elevation myocardial infarction or unstable angina pectoris enrolled in the multinational global registry of acute coronary events, Gilles Montalescot, Omar H. Dabbous, Michael J. Lim, Marcus D. Flather, Rajendra H. Mehta, and GRACE Investigators

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Access to catheterisation facilities in patients admitted with acute coronary syndrome: multinational registry study, Frans Van de Werf, Joel M. Gore, Alvaro Avezum, Dietrich C. Gulba, Shaun G. Goodman, Andrzej Budaj, David Brieger, Kami White, Keith A. A. Fox, Kim A. Eagle, Brian M. Kennelly, and GRACE Investigators