The Department of Cell and Developmental Biology at the University of Massachusetts Medical School is at the center of exciting new advances in understanding basic biological and biomedical processes to promote clinical and translational science. Research addresses the organization, assembly and activity of the regulatory machinery for cell growth and aging, differentiation and development, as well as genetic and epigenetic control of gene expression in human embryonic stem cells and lineage committed cells; with implications for treatment of cancers, bone diseases, reproductive disorders, genetic conditions and neurodegenerative and psychiatric disorders. This collection showcases the books, journal articles, book reviews, and other publications and presentations written by faculty and researchers of the Department of Cell and Developmental Biology.

Submissions from 2009

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The influence of endocrine disruptors on pubertal timing, Elka Jacobson-Dickman and Mary M. Lee (Current opinion in endocrinology, diabetes, and obesity)

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Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice, Ya-Huei Kuo, Sayyed K. Zaidi, Svetlana Gornostaeva, Toshihisa Komori, Gary S. Stein, and Lucio H. Castilla (Blood)

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Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro, Nichole E. Lapointe, Peleg M. Horowitz, Angela L. Guillozet-Bongaarts, Andres Silva, Athena Andreadis, and Lester I. Binder (Biochemistry)

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The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella, Karl-Ferdinand Lechtreck, Eric C. Johnson, Tsuyoshi Sakai, Deborah A. Cochran, Bryan A. Ballif, John Rush, Gregory J. Pazour, Mitsuo Ikebe, and George B. Witman (The Journal of cell biology)

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HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B, Karl-Ferdinand Lechtreck, Scott Luro, Junya Awata, and George B. Witman (Cell motility and the cytoskeleton)

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High-speed digital imaging of ependymal cilia in the murine brain, Karl-Ferdinand Lechtreck, Michael J. Sanderson, and George B. Witman (Methods in cell biology)

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Tropomyosin and the steric mechanism of muscle regulation, William Lehman and Roger W. Craig (Advances in experimental medicine and biology)

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Structural basis for the activation of muscle contraction by troponin and tropomyosin, William Lehman, Agnieszka Galinska-Rakoczy, Victoria Hatch, Larry S. Tobacman, and Roger W. Craig (Journal of molecular biology)

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Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation, Zhaoyong Li, Mohammad Q. Hassan, Mohammed Jafferji, Rami I. Aqeilan, Ramiro Garzon, Carlo M. Croce, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (The Journal of biological chemistry)

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CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P, Partha Mitra, Prachi N. Ghule, Margaretha Van der Deen, Ricardo F. Medina, Ronglin Xie, William F. Holmes, Xin Ye, Keiichi I. Nakayama, J. Wade Harper, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen (Journal of cellular physiology)

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The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells, Samisubbu R. Naidu, Ian M. Love, Anthony N. Imbalzano, Steven R. Grossman, and Elliot J. Androphy (Oncogene)

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The biochemistry of RNA metabolism studied in situ, Jeffrey A. Nickerson (RNA biology)

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Do Atypical Antipsychotic Agents Trigger Autoimmune Diabetes?, Benjamin U. Nwosu, Olga T. Hardy, Amanda Angelescu, Leslie A. Soyka, and Mary M. Lee (Endocrinologist)

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Pseudohypoparathyroidism type 1a and insulin resistance in a child, Benjamin U. Nwosu and Mary M. Lee (Nature reviews. Endocrinology)

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The Chlamydomonas Flagellum as a Model for Human Ciliary Disease, Gregory J. Pazour and George B. Witman (The Chlamydomonas Sourcebook)

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Refined genomic localization of the genetic lesion in the osteopetrosis (op) rat and exclusion of three positional and functional candidate genes, Clcn7, Atp6v0c, and Slc9a3r2, B. Perdu, Paul R. Odgren, Liesbeth van Wesenbeeck, K. Jennes, Carole A. MacKay, and W. Van Hul (Calcified tissue international)

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Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1), Barry P. Pereira, Ye-fang Zhou, Anurag Gupta, David T. Leong, Khin Zarchi Zarchi Aung, Ling Ling, Robert W. H. Pho, Mario Galindo, Manuel Salto-Tellez, Gary S. Stein, Simon M. Cool, Andre J. Van Wijnen, and Saminathan S. Nathan (Journal of cellular physiology)

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Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression, Jitesh Pratap, Karen M. Imbalzano, Jean. M. Underwood, Nathalie Cohet, Karthiga Devi Gokul, Jacqueline Akech, Andre J. Van Wijnen, Janet L. Stein, Anthony N. Imbalzano, Jeffrey A. Nickerson, Jane B. Lian, and Gary S. Stein (Cancer research)

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Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells, Inga A. San Martin, Nelson Varela, Marcia Gaete, Karina Villegas, Mariana Osorio, Julio Tapia, Marcelo Antonelli, Edna E. Mancilla, Barry P. Pereira, Saminathan S. Nathan, Jane B. Lian, Janet L. Stein, Gary S. Stein, Andre J. Van Wijnen, and Mario Galindo (Journal of cellular physiology)

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Pluripotency: toward a gold standard for human ES and iPS cells, Kelly P. Smith, Mai X. Luong, and Gary S. Stein (Journal of cellular physiology)

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Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan (Annals of the New York Academy of Sciences)

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Transcription-factor-mediated epigenetic control of cell fate and lineage commitment, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan (Biochemistry and cell biology = Biochimie et biologie cellulaire)

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Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation, Marcela Stuardo, Milka Martinez, Karla Hildago, Martin A. Montecino, Amjad Javed, Jane B. Lian, Gary S. Stein, Janet L. Stein, and Soraya E. Gutierrez (Journal of cellular physiology)

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The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts, Nadiya M. Teplyuk, Larisa M. Haupt, Ling Ling, Christian Dombrowski, Foong Kin Mun, Saminathan S. Nathan, Jane B. Lian, Janet L. Stein, Gary S. Stein, Simon M. Cool, and Andre J. Van Wijnen (Journal of cellular biochemistry)

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The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts, Nadiya M. Teplyuk, Ying Zhang, Yang Lou, John R. Hawse, Mohammad Q. Hassan, Viktor Teplyuk, Jitesh Pratap, Mario Galindo, Janet L. Stein, Gary S. Stein, Jane B. Lian, and Andre J. Van Wijnen (Molecular endocrinology (Baltimore, Md.))

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The tail binds to the head-neck domain, inhibiting ATPase activity of myosin VIIA, Nobuhisa Umeki, HyunSuk Jung, Shinya Watanabe, Tsuyoshi Sakai, Xiang-Dong Li, Reiko Ikebe, Roger W. Craig, and Mitsuo Ikebe (Proceedings of the National Academy of Sciences of the United States of America)

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Heterogeneous nuclear ribonucleoprotein E3 modestly activates splicing of tau exon 10 via its proximal downstream intron, a hotspot for frontotemporal dementia mutations, Yan Wang, Lei Gao, Sze-Wah Tse, and Athena Andreadis (Gene)

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IC97 is a novel intermediate chain of I1 dynein that interacts with tubulin and regulates interdoublet sliding, Maureen Wirschell, Chun Yang, Pinfen Yang, Laura Fox, Haru-aki Yanagisawa, Ritsu Kamiya, George B. Witman, Mary E. Porter, and Winfield S. Sale (Molecular biology of the cell)

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Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor, John J. Wixted, Paul J. Fanning, Tripti Gaur, Shannon L. O'Connell, Jason Silva, April Mason-Savas, David C. Ayers, Gary S. Stein, and Jane B. Lian (Journal of cellular physiology)

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FSHD region gene 1 (FRG1) is crucial for angiogenesis linking FRG1 to facioscapulohumeral muscular dystrophy-associated vasculopathy, Ryan Wuebbles, Meredith L. Hanel, and Peter L. Jones (Disease models and mechanisms)

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A single base pair mutation encoding a premature stop codon in the MIS type II receptor is responsible for canine persistent Mullerian duct syndrome, Wenfang Wu, Shengqin Wan, Pujar Shashikant, Mark E. Haskins, Donald H. Schlafer, Mary M. Lee, and Vicki N. Meyers-Wallen (Journal of andrology)

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Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network, Sayyed K. Zaidi, Christopher R. Dowdy, Andre J. Van Wijnen, Jane B. Lian, Azra Raza, Janet L. Stein, Carlo M. Croce, and Gary S. Stein (Cancer research)

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Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response, Xinna Zhang, Lin Lin, Huarong Guo, Jianhua Yang, Stephen N. Jones, Aart Jochemsen, and Xiongbin Lu (Cancer research)

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The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells, Ying Zhang, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular biochemistry)

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Analysis of tarantula skeletal muscle protein sequences and identification of transcriptional isoforms, Jingui Zhu, Yongqiao Sun, Fa-Qing Zhao, Jun Hu, Roger W. Craig, and Songnian Hu (BMC genomics)

Submissions from 2008

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Three-dimensional reconstruction of tarantula myosin filaments suggests how phosphorylation may regulate myosin activity, Lorenzo Alamo, Willy Wriggers, Antonio Pinto, Fulvia Bartoli, Leiria Salazar, Fa-Qing Zhao, Roger W. Craig, and Raul Padron (Journal of molecular biology)

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Phenotypic transcription factors epigenetically mediate cell growth control, Syed A. Ali, Sayyed K. Zaidi, Caroline S. Dacwag, Nunciada Salma, Daniel W. Young, A. Rauf Shakoori, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Anthony N. Imbalzano, Gary S. Stein, and Janet L. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism, Rami I. Aqeilan, Mohammad Q. Hassan, Alain de Bruin, John P. Hagan, Stefano Volinia, Titziana Palumbo, Sadiq Hussain, Suk Hee Lee, Tripti Gaur, Gary S. Stein, Jane B. Lian, and Carlo M. Croce (The Journal of biological chemistry)

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The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes, Rachit Bakshi, Sayyed K. Zaidi, Sandhya Pande, Mohammad Q. Hassan, Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Journal of cell science)

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NHA-oc/NHA2: a mitochondrial cation-proton antiporter selectively expressed in osteoclasts, Ricardo A. Battaglino, L. Pham, Leslie R. Morse, M. Vokes, A. Sharma, Paul R. Odgren, Meilheng Yang, Hajime Sasaki, and Philip Stashenko (Bone)

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ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage, Lufen Chang, Bingsen Zhou, Shuya Hu, Robin Guo, Xiyong Liu, Stephen N. Jones, and Yun Yen (Proceedings of the National Academy of Sciences of the United States of America)

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The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis, Agnes Delaunay, Kenneth D. Bromberg, Yukiko Hayashi, Massimiliano Mirabella, Denise Burch, Brian Kirkwood, Carlo Serra, May C. Malicdan, Andrew P. Mizisin, Roberta Morosetti, Aldobrando Broccolini, Ling T. Guo, Stephen N. Jones, Sergio A. Lira, Pier Lorenzo Puri, G. Diane Shelton, and Ze'ev Ronai (PloS one)

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Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia, Assam El-Osta, Daniella Brasacchio, Dachun Yao, Alessandro Pocai, Peter L. Jones, Robert G. Roeder, Mark E. Cooper, and Michael Brownlee (The Journal of experimental medicine)

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Regulating the acrosome reaction, Harvey M. Florman, Melissa K. Jungnickel, and Keith A. Sutton (The International journal of developmental biology)

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Structural basis for the regulation of muscle contraction by troponin and tropomyosin, Agnieszka Galinska-Rakoczy, Patti Engel, Chen Xu, HyunSuk Jung, Roger W. Craig, Larry S. Tobacman, and William Lehman (Journal of molecular biology)

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Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells, Kerri L. George, Laura H. Saltman, Gary S. Stein, Jane B. Lian, and Robert B. Zurier (Journal of cellular physiology)

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The gonadotropin-releasing hormone (GnRH) neuronal population is normal in size and distribution in GnRH-deficient and GnRH receptor-mutant hypogonadal mice, John C. Gill, Brandon Wadas, Peilin Chen, Wendy Portillo, Andrea Reyna, Elisa Jorgensen, Shaila Mani, Gerald A. Schwarting, Suzanne M. Moenter, Stuart A. Tobet, and Ursula B. Kaiser (Endocrinology)

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X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected, Lisa L. Hall, Meg Byron, John T. Butler, Klaus A. Becker, Angel Nelson, Michal Amit, Joseph Itskovitz-Eldor, Janet L. Stein, Gary S. Stein, Carol Ware, and Jeanne B. Lawrence (Journal of cellular physiology)

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Association of blood lead levels with onset of puberty in Russian boys, Russ Hauser, Oleg Sergeyev, Susan Korrick, Mary M. Lee, Boris Revich, Elana Gitin, Jane S. Burns, and Paige L. Williams (Environmental health perspectives)

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Mammalian SNM1 is required for genome stability, A. W. Hemphill, D. Bruun, L. Thrun, Y. Akkari, Y. Torimaru, K. Hejna, P. M. Jakobs, J. Hejna, Stephen N. Jones, S. B. Olson, and R. E. Moses (Molecular genetics and metabolism)

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Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal, Amjad Javed, Jong-Sup Bae, Faiza Afzal, Soraya E. Gutierrez, Jitesh Pratap, Sayyed K. Zaidi, Yang Lou, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (The Journal of biological chemistry)

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Ca2+ -induced tropomyosin movement in scallop striated muscle thin filaments, HyunSuk Jung and Roger W. Craig (Journal of molecular biology)

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Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells, HyunSuk Jung, Satoshi Komatsu, Mitsuo Ikebe, and Roger W. Craig (Molecular biology of the cell)

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Intravascular uptake during fluoroscopically guided cervical interlaminar steroid injection at C6-7: a case report, Mark S. Kaplan, Joseph Cunniff, John Cooke, and Jeremy Giere Collins (Archives of physical medicine and rehabilitation)

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Binding of ATP to UAP56 is necessary for mRNA export, Krishna P. Kota, Stefan R. Wagner, Elvira Huerta, Jean. M. Underwood, and Jeffrey A. Nickerson (Journal of cell science)

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Mutations in Hydin impair ciliary motility in mice, Karl-Ferdinand Lechtreck, Philippe Delmotte, Michael L. Robinson, Michael J. Sanderson, and George B. Witman (The Journal of cell biology)

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The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va, Xiang-Dong Li, HyunSuk Jung, Qizhi Wang, Reiko Ikebe, Roger W. Craig, and Mitsuo Ikebe (Proceedings of the National Academy of Sciences of the United States of America)

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Human embryonic stem cell registries: value, challenges and opportunities, Mai X. Luong, Kelly P. Smith, and Gary S. Stein (Journal of cellular biochemistry)

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Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle, Pradeep K. Luther, Pauline M. Bennett, Carlo Knupp, Roger W. Craig, Raul Padron, Samantha P. Harris, Jitendrakumar Patel, and Richard L. Moss (Journal of molecular biology)

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MdmX regulates transformation and chromosomal stability in p53-deficient cells, Zdenka Matijasevic, Anna Krzywicka-Racka, Greenfield Sluder, and Stephen N. Jones (Cell cycle (Georgetown, Tex.))

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Initial acceptance of treatment with antihypertensive medication: The importance of communication, trust and beliefs, Kathleen M. Mazor, Melissa A. Fischer, and Susan Billings-Gagliardi (Journal of Communication in Healthcare)

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The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif, Ricardo F. Medina, Timothy F. Buck, Sayyed K. Zaidi, Angela Miele, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Biochemistry)

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MicroRNAs 221 and 222 bypass quiescence and compromise cell survival, Ricardo F. Medina, Sayyed K. Zaidi, Chang-Gong Liu, Janet L. Stein, Andre J. Van Wijnen, Carlo M. Croce, and Gary S. Stein (Cancer research)

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Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells, Rajini R. Mudhasani, Zhiqing Zhu, Gyorgy Hutvagner, Christine M. Eischen, Stephen Lyle, Lisa L. Hall, Jeanne B. Lawrence, Anthony N. Imbalzano, and Stephen N. Jones (The Journal of cell biology)

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Evaluation of short and tall stature in children, Benjamin U. Nwosu and Mary M. Lee (American family physician)

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Multifetal Pregnancy May Increase the Risk for Severe Maternal and Neonatal Vitamin D Deficiency, Benjamin U. Nwosu, Leslie A. Soyka, Amanda Angelescu, Olga T. Hardy, and Mary M. Lee (Endocrinologist)

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Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte stress 1 gene promoter, Samir Ounzain, Caroline S. Dacwag, Nilesh J. Samani, Anthony N. Imbalzano, and Nelson W. Chong (BMC molecular biology)

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Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes, Sandhya Pande, Syed A. Ali, Christopher R. Dowdy, Sayyed K. Zaidi, Kosei Ito, Yoshiaki Ito, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular physiology)

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In situ nuclear organization of regulatory machinery, Shirwin M. Pockwinse, Sayyed K. Zaidi, Ricardo F. Medina, Rachit Bakshi, Krishna P. Kota, Syed A. Ali, Daniel W. Young, Jeffrey A. Nickerson, Amjad Javed, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Methods in molecular biology (Clifton, N.J.))

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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells, Jitesh Pratap, John J. Wixted, Tripti Gaur, Sayyed K. Zaidi, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Cancer research)

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Cyclin E in centrosome duplication and reduplication in sea urchin zygotes, Bradley J. Schnackenberg, William F. Marzluff, and Greenfield Sluder (Journal of cellular physiology)

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Olfactory axon guidance: the modified rules, Gerald A. Schwarting and Timothy R. Henion (Journal of neuroscience research)

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Gene expression in nuclear microenvironments for biological control and cancer, Gary S. Stein (Cancer biology and therapy)

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Nuclear microenvironments and cancer, Gary S. Stein, James R. Davie, J. Randy Knowlton, and Sayyed K. Zaidi (Journal of cellular biochemistry)

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Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan (Journal of cellular biochemistry)

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A polycystin-1 controls postcopulatory reproductive selection in mice, Keith A. Sutton, Melissa K. Jungnickel, and Harvey M. Florman (Proceedings of the National Academy of Sciences of the United States of America)

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Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development, Brune Trevant, Tripti Gaur, Sadiq Hussain, John Symons, Barry S. Komm, Peter V. N. Bodine, Gary S. Stein, and Jane B. Lian (Journal of cellular physiology)

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Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells, Margaretha Van der Deen, Mohammad Q. Hassan, Jitesh Pratap, Nadiya M. Teplyuk, Daniel W. Young, Amjad Javed, Sayyed K. Zaidi, Jane B. Lian, Martin A. Montecino, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen (Methods in molecular biology (Clifton, N.J.))

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Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells, P. Wang, T. Lushnikova, Jessica Odvody, T. C. Greiner, Stephen N. Jones, and Christine M. Eischen (Oncogene)

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Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation, Meilheng Yang, Mark J. Birnbaum, Carole A. MacKay, April Mason-Savas, Benjamin Thompson, and Paul R. Odgren (Journal of cellular physiology)

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Suppression of human tumor cell proliferation by Smurf2-induced senescence, Hong Zhang, Yuchin Teng, Yahui Kong, Paul E. Kowalski, and Stanley N. Cohen (Journal of cellular physiology)

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Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors, Shuo Zhang, Lambert Edelmann, June Liu, James E. Crandall, and Maria A. Morabito (The Journal of neuroscience : the official journal of the Society for Neuroscience)

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Millisecond time-resolved changes occurring in Ca2+-regulated myosin filaments upon relaxation, Fa-Qing Zhao and Roger W. Craig (Journal of molecular biology)

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Head-head interaction characterizes the relaxed state of Limulus muscle myosin filaments, Fa-Qing Zhao, Roger W. Craig, and John L. Woodhead (Journal of molecular biology)

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Blebbistatin stabilizes the helical order of myosin filaments by promoting the switch 2 closed state, Fa-Qing Zhao, Raul Padron, and Roger W. Craig (Biophysical journal)

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Three-dimensional structure of vertebrate cardiac muscle myosin filaments, Maria E. Zoghbi, John L. Woodhead, Richard L. Moss, and Roger W. Craig (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 2007

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Targeted deletion of Wwox reveals a tumor suppressor function, Rami I. Aqeilan, Francesco Trapasso, Sadiq Hussain, Stefan Costinean, Dean Marshall, Yuri Pekarsky, John P. Hagan, Nicola Zanesi, Mohamed Kaou, Gary S. Stein, Jane B. Lian, and Carlo M. Croce (Proceedings of the National Academy of Sciences of the United States of America)

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The tripartite motif (TRIM) of nuclear factor 7 is required for its association with transcription units, Brent Beenders, Peter L. Jones, and Michel Bellini (Molecular and Cellular Biology)

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Student decisions about lecture attendance: do electronic course materials matter, Susan Billings-Gagliardi and Kathleen M. Mazor (Academic medicine : journal of the Association of American Medical Colleges)

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p19Ink4d and p18Ink4c cyclin-dependent kinase inhibitors in the male reproductive axis, Gregory M. Buchold, Patricia L. Magyar, Ramamani Arumugam, Mary M. Lee, and Deborah A. O'Brien (Molecular reproduction and development)

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Inducible XIST-dependent X-chromosome inactivation in human somatic cells is reversible, Jennifer C. Chow, Lisa L. Hall, Sarah E.L. Baldry, Nancy P. Thorogood, Jeanne B. Lawrence, and Carolyn J. Brown (Proceedings of the National Academy of Sciences of the United States of America)

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Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts, Mario Galindo, Rachel A. Kahler, Nadiya M. Teplyuk, Janet L. Stein, Jane B. Lian, Gary S. Stein, Jennifer J. Westendorf, and Andre J. Van Wijnen (Journal of molecular histology)

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Patterning the developing and regenerating olfactory system, Timothy R. Henion and Gerald A. Schwarting (Journal of cellular physiology)

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Working with classic video, Edward H. Hinchcliffe and Greenfield Sluder (Methods in cell biology)

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Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella, Yuqing Hou, Hongmin Qin, John A. Follit, Gregory J. Pazour, Joel L. Rosenbaum, and George B. Witman (The Journal of cell biology)

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Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella, Kaiyao Huang, Dennis R. Diener, Aaron Mitchell, Gregory J. Pazour, George B. Witman, and Joel L. Rosenbaum (The Journal of cell biology)

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Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility, Karl-Ferdinand Lechtreck and George B. Witman (The Journal of cell biology)

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Temporal evolution of gene expression in rat carotid artery following balloon angioplasty, Jian-ming Li, Xueqing Zhang, Peter R. Nelson, Paul R. Odgren, Janice D. Nelson, Calin A. Vasiliu, Jane Park, Marvin Morris, Jane B. Lian, Bruce S. Cutler, and Peter E. Newburger (Journal of cellular biochemistry)

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Centriole biogenesis: a tale of two pathways, Jadranka Loncarek, Greenfield Sluder, and Alexey Khodjakov (Nature cell biology)

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The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop, Xiongbin Lu, Ou Ma, Thuy-Ai Nguyen, Stephen N. Jones, Moshe Oren, and Lawrence A. Donehower (Cancer cell)